Laguna Hills, CA Medical Office Space for Rent & Lease

$2 SF/Yr

21,300 SF

Renovated Medical Office Building

24953 Paseo De Valencia Bldg C, Laguna Hills, CA 92653

Recently renovated medical office building near Saddleback Hospital.

Recently renovated exterior with a modern, upscale design.
Convenient and abundant patient parking.
Professionally managed medical office building.
Located near Saddleback Memorial Medical Center.
Great natural light inside the suites.

Updated: Nov 21, 2025

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Medical/Office Building Near Irvine Spectrum

$1.75 SF/Yr

6,800 SF

Medical/Office Building Near Irvine Spectrum

22921, 22931 & 22941 Triton Way, Laguna Hills, CA 92653

Two-story medical and office building with recent renovations and ample parking.

Prime South Orange County location
Excellent access to the 405, 133 & 5 Freeways and Toll Roads
Major renovations just completed
Near Irvine Spectrum Center
Near newly developed luxury residential

Updated: Nov 26, 2025

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2,858 SF

Medical Office Building For Lease

Freestanding medical office building featuring multiple offices and amenities.

23173 La Cadena Dr, Laguna Hills, CA

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Medical Office Near Saddleback Hospital

Medical office space within walking distance of Saddleback Memorial.

24012-24022 Calle De La Plata, Laguna Hills, CA 92653

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40,000 SF

Medical Office Space For Rent

New medical office space adjacent to Saddleback Memorial Hospital.

24401 Calle De La Louisa, Laguna Hills, CA 92653

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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 5 Active listings in Laguna Hills, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

$6,915/Mo

1,500 SF

Irvine Office Sublease Opportunity

Professional Irvine office space available for sublease in prime location.

22 Odyssey, Irvine, CA 92618

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$2 SF/Yr

2,360 SF

Medical Office Condo For Rent

Medical office condo featuring private offices, conference room, and balcony.

30212 Tomas, Rancho Santa Margarita, CA

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18,400 SF

Medical Office Space For Rent

Medical office space in Rancho Santa Margarita available for lease.

29472 Avenida de las Banderas, Rancho Santa Margarita, CA 92688

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114,209 SF

Irvine Medical Plaza Office Suites

Medical office suites for lease in Irvine Spectrum submarket.

114 Pacifica, Irvine, CA 92618

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Similar Spaces for Sale in Laguna Hills, CA

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

$49,900

574 SF

Laguna Hills Office Condo

Office condo for sale or lease in Laguna Hills.

23232 Peralta Drive 117, Laguna Hills, CA 92653

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$9,656/Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505

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$17,728/Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505

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$3,600/Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905

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4,000 SF

Office Development Land For Lease

2.43 acres for office development with build-to-suit opportunity.

1323 Strawfloor Drive, Jonesboro, AR 72401

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Laguna Hills, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Laguna Hills, CA with 5 listings featured on our commercial real estate exchange. The current inventory includes 28,100 square feet of properties with an estimated lease value of $4 SF/Yr.

Estimated lease rates for Medical Office Space in Laguna Hills, CA begin at $1.75 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.