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    Cape Girardeau County, MO Healthcare Properties for Sale

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    Ambulatory Surgery Center Investment Opportunity
    $8,050,000
    13,650 SF

    Ambulatory Surgery Center Investment Opportunity

    3241 Percy Drive, Cape Girardeau, MO 63701

    Single-tenant surgery center near St. Francis Medical Center for sale.

    • 13,650 sq. ft. single‑tenant ambulatory surgery center.
    • Located directly across from St. Francis Medical Center (Level III trauma center).
    • Turnkey investment with 2 years remaining on the current lease and 2% annual rental increases.
    • New, state‑of‑the‑art HVAC system (valued at over $800,000).
    • Specializes in key medical areas (ENT, general surgery, gynecology, ophthalmology, orthopedics, retinal).
    Updated: Sep 9, 2025
    View details
    Versatile Commercial Building on 1.9 Acres
    $2,900,000
    13,458 SF

    Versatile Commercial Building on 1.9 Acres

    1429 N Mount Auburn Road, Cape Girardeau, MO 63701

    All-brick commercial building with abundant parking and multiple use opportunities.

    • Versatile commercial building suitable for multiple uses
    • Potential for dual income stream: owner‑occupy main level and lease lower level
    • Abundant parking with 70+ spaces and a large front entry canopy
    • Well‑maintained building with recent updates including remodeled interior
    • Equipped with a 2,000 lb capacity elevator
    Updated: Mar 12
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    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau County, MO, we suggest exploring several alternatives: similar 10 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Paducah Commercial Land
    $600,000
    1.97 Acres

    Prime Paducah Commercial Land

    1.97 acres ideal for retail, medical, or restaurant use.

    3620 James Sanders Blvd, Paducah, KY 42001
    View details
    Prime Commercial Tract in Paducah
    $1,475,000
    16.50 Acres

    Prime Commercial Tract in Paducah

    16.5 acre commercial tract with high visibility and access.

    3020 Wayne Sullivan Drive, Paducah, KY 42003
    View details
    Commercial Land in Poplar Bluff
    $399,000
    6.64 Acres

    Commercial Land in Poplar Bluff

    6.64 acres of commercial land ready for development.

    3387 Kanell Boulevard, Poplar Bluff, MO 63901
    View details
    Fulton Commercial Development Site
    $1,150,000
    33.60 Acres

    Fulton Commercial Development Site

    33-acre commercial development site in Fulton, KY, near I-69.

    Myatt Road, Fulton, KY 42041
    View details

    Explore Off-Market Properties in Cape Girardeau County, MO

    Consider similar Off-Market properties in Cape Girardeau County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    430 Frederick St

    430 Frederick St

    HOMES (RETIRED, NURSING) • 11,218 SF
    Value Estimation by Request
    430 Frederick St, Cape Girardeau, MO 63701-4835
    View details
    914 Old Cpe Rd

    914 Old Cpe Rd

    HOMES (RETIRED, NURSING) • 8,640 SF
    Value Estimation by Request
    914 Old Cpe Rd, Jackson, MO 63755-2261
    View details
    2906 Beaver Crk Dr

    2906 Beaver Crk Dr

    HOMES (RETIRED, NURSING) • 6,721 SF
    Value Estimation by Request
    2906 Beaver Crk Dr, Cape Girardeau, MO 63701-1732
    View details
    2525 Boutin Dr

    2525 Boutin Dr

    HOMES (RETIRED, NURSING) • 26,911 SF
    Value Estimation
    $575,000
    2525 Boutin Dr, Cape Girardeau, MO 63701-8551
    View details
    Silver Springs Rd

    Silver Springs Rd

    Individual retail properties • 4.56 Acres
    Value Estimation by Request
    0 Silver Springs Rd, Cape Girardeau, MO 63703
    View details
    3049 William St

    3049 William St

    Medical Office Space • 79,122 SF
    Value Estimation by Request
    3049 William St, Cape Girardeau, MO 63703
    View details
    670 Broadridge Dr

    670 Broadridge Dr

    HOMES (RETIRED, NURSING) • 2,505 SF
    Value Estimation
    $600,000
    670 Broadridge Dr, Jackson, MO 63755-3044
    View details
    325 Sprigg St

    325 Sprigg St

    HOMES (RETIRED, NURSING) • 1,913 SF
    Value Estimation by Request
    325 Sprigg St, Cape Girardeau, MO 63701-5531
    View details
    2001 Kingshighway St

    2001 Kingshighway St

    HOMES (RETIRED, NURSING) • 13,006 SF
    Value Estimation by Request
    2001 Kingshighway St, Cape Girardeau, MO 63701-2127
    View details
    2915 Cpe Lacroix Rd

    2915 Cpe Lacroix Rd

    HOMES (RETIRED, NURSING) • 11,978 SF
    Value Estimation by Request
    2915 Cpe Lacroix Rd, Cape Girardeau, MO 63701-9766
    View details

    Cape Girardeau County, MO Healthcare Properties Investment Opportunities Market Analysis

    Explore 12 healthcare properties for sale in Cape Girardeau County, MO on our real estate platform. These investment opportunities span a total of 27,108 square feet of properties for sale, with an estimated market value of $10,950,000.

    Sale prices for medical real estate in Cape Girardeau County, MO start at $2,900,000, averaging $5,475,000, and reaching up to $8,050,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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