Cape Girardeau County, MO Retail properties & Spaces for sale

$700,000

7,200 SF

Warehouse with Showroom and Shop Space

3082 County Road 620, Cape Girardeau, MO 63701

Purchase a 7,200 SF warehouse with dedicated showroom, shop area, and framed upstairs space for flexible business or storage needs.

7,200 SF warehouse with approx. 2,400 SF finished showroom/retail or office space and 3,600 SF shop area
Additional 1,200 SF upstairs area is framed and ready to be finished as living quarters, office space, or storage
Two large garage doors for convenient access and workflow
Central air and forced‑air heating
Metal siding exterior and concrete flooring

Updated: Jun 5

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$569,900

3,096 SF

Versatile Commercial Building Near I-55

5598 Us Highway 61 North, Jackson, MO 63755

High-traffic location, built in 2017, suitable for diverse businesses.

High‑traffic location with highway/interstate frontage.
Built in 2017 with maintenance‑free exterior and roof.
Originally designed as a restaurant with a full commercial kitchen and seating for 90.
County with no zoning restrictions allows for diverse business opportunities.
Open floor plan and ample parking.

Updated: Apr 13

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$895,000

7,000 SF

Mixed-Use Building in Prime Location

Turn-key mixed-use building in a high-traffic Jackson location.

246 W Deerwood Drive, Jackson, MO 63755

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Renovated Commercial Building in Cape Girardeau

$239,900

2,937 SF

Renovated Commercial Building in Cape Girardeau

Renovated commercial building with high visibility in a prime location.

230 N Sprigg Street, Cape Girardeau, MO 63701

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Versatile Commercial Building in Missouri

$199,900

1,800 SF

Versatile Commercial Building in Missouri

Adaptable 1800 sq ft commercial building in Cape Girardeau.

2357 Rust Avenue, Cape Girardeau, MO 63703

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Versatile Riverfront Commercial Property

$400,000

4,400 SF

Versatile Riverfront Commercial Property

Prime riverfront property suitable for office, restaurant, warehouse, or mixed-use.

450 N Main Street, Cape Girardeau, MO 63701

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$295,000

2,920 SF

Versatile Commercial Property For Sale

High-visibility commercial property with flexible layout and spacious attached warehouse.

225 Clark Avenue, Cape Girardeau, MO 63701

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Turn-Key Restaurant Business Opportunity

$200,000

2,760 SF

Turn-Key Restaurant Business Opportunity

Fully operational restaurant, ready for new owner in Oak Ridge.

4053 State Highway E, Oak Ridge, MO 63769

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$475,000

7,044 SF

Versatile Riverfront Commercial Property

Flexible commercial space with riverfront location and development potential.

308 N Main Street, Cape Girardeau, MO 63701

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Broadway Commercial Space with Apartment

$280,000

2,900 SF

Broadway Commercial Space with Apartment

Versatile commercial space with remodeled apartment in prime location.

520 Broadway Street, Cape Girardeau, MO 63701

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$299,900

5,262 SF

Equipped Shop Property Near Jackson

Fully equipped shop on 1 acre near Missouri Route 72.

7276 State Highway 72, Jackson, MO 63755

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$239,900

2,937 SF

Renovated Commercial Building on Sprigg

Renovated commercial space with high visibility and income potential.

230 N Sprigg Street, Cape Girardeau, MO 63701

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$825,000

7,396 SF

Versatile Commercial Space in Downtown

7,396 SF commercial building with multiple dining areas.

20 N Spanish Street, Cape Girardeau, MO 63701

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Broadway Commercial Opportunity For Sale

$1,200,000

3,600 SF

Broadway Commercial Opportunity For Sale

Commercial property with renovated kitchen, patio, and high visibility.

632 Broadway Street, Cape Girardeau, MO 63701

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Retail Property in High Visibility Location

$375,000

0.67 Acres

Retail Property in High Visibility Location

Two-level retail space with 16 parking spots in Jackson, MO.

1336 Clover Drive, Jackson, MO 63755

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Freestanding Restaurant in Growing Community

$867,000

3,000 SF

Freestanding Restaurant in Growing Community

Freestanding restaurant with drive-through in a high-traffic location.

421 E Jackson Blvd, Jackson, MO

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1,450 SF

High Traffic Retail/Office Space

Neighborhood center with high visibility and excellent tenant mix.

2500 - 2536 William, Cape Girardeau, MO 63703

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$219,000

1,716 SF

E. Jackson Blvd Retail/Office Building

Creative office or retail building in high-traffic, visible location.

1204 E Jackson Blvd, Jackson, MO 63755

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Freestanding Restaurant in Cape Girardeau

$1,950,000

5,396 SF

Freestanding Restaurant in Cape Girardeau

Single-tenant restaurant with a new long-term lease.

202 S Broadview St, Cape Girardeau, MO

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4,500 SF

Prime Retail Space in Cape

4,500 SF retail space in historic downtown Cape Girardeau.

731 Broadway St, Cape Girardeau, MO 63701

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5.13 Acres

Retail/Office Space Near I-55

Prime location near I-55 and West Park Mall.

3065 William, Cape Girardeau, MO 63703

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46,000 SF

Cape Girardeau Retail Opportunity

46,000 SF retail space in West Cape Centre.

201 S Broadview St, Cape Girardeau, MO 63703

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Cape Girardeau Commercial Space Available

Contact for pricing

1,250 SF

Cape Girardeau Commercial Space Available

Flexible commercial space for office, retail, or service businesses.

151 S Mount Auburn Rd, Cape Girardeau, MO 63703

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1,660 SF

Prime Commercial Space on Mount Auburn

Versatile commercial space with parking and high visibility.

326 S. Mount Auburn, Cape Girardeau, MO 63703

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Cape Girardeau County, MO Retail Properties & Spaces Investment Opportunities Market Analysis

Explore 36 retail properties & spaces for sale in Cape Girardeau County, MO, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 73,564 square feet of properties for sale, with an estimated market value of $10,780,600.

Sale prices for stores in Cape Girardeau County, MO start at $200,000, averaging $634,152, and reaching up to $1,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.