Cape Girardeau County, MO Office buildings for sale

Updated: Apr 15

Renovated Downtown Office and Retail Building

230 N Sprigg Street, Cape Girardeau, MO 63701

$239,900

2,937 sqft 0.25 AC lot

Almost 3,000 sq ft of renovated interior space in a brick building
Brand‑new roof, gutters, central A/C, flooring, fixtures, bathrooms, kitchenette, siding, and newly tuckpointed exterior
Road frontage on N Sprigg St in the downtown business district
Heating: forced air; cooling: central air and electric
Flat roof and parking lot with open parking options

View details

Updated: Mar 20

Updated Office Building with Parking

824 Independence Street, Cape Girardeau, MO 63703

$350,000

0.42 AC lot

Well‑maintained, updated office building built in 1968 with brick construction
Heating: forced air; cooling: central air
Flooring includes linoleum and carpet
Located on Independence with strong daily traffic counts
Includes ample on‑site parking and excellent visibility

View details

Multi-Level Office Building with Parking

4012 E Jackson Boulevard, Jackson, MO 63755

$249,900

0.59 AC lot

Three-level building with parking and a two-bed, one-bath unit on the third level.

View details

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Two-Level Office Building For Sale

10 Doctors Park, Cape Girardeau, MO 63703

$815,000

9,857 sqft 0.44 AC lot

9,857 SF office building with multiple offices and restrooms.

View details

Two-Level Office Building with Parking

1336 Clover Drive, Jackson, MO 63755

$375,000

0.67 AC lot

Two-level accessible office space offering 16 parking spaces on a 0.67-acre lot.

View details

Downtown Office Building For Sale

18 N. Main, Cape Girardeau, MO 63701

$899,900

13,694 sqft

13,694 SF office building in historic downtown Cape Girardeau.

View details

Renovated Mid-Century Office Building

429 N Broadview Street, Cape Girardeau, MO 63701

Contact for pricing

15,831 sqft

Updated office building with multiple private offices, conference rooms, and an event space with bar and projection screen.

View details

Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 7 Active listings in Cape Girardeau County, MO, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Development Land Site

103 Grove Estates, Sikeston, MO 63801

$144,000

1.01 AC lot

Commercially zoned tract with Highway 61 frontage for office, medical, and professional services near Sikeston residential areas.

View details

Corner Commercial Land with Road Frontage

1324 W Saint Joseph Street, Perryville, MO 63775

$972,000

1,092 sqft 0.94 AC lot

Zoned C-2 commercial land with 180 feet of road frontage and ingress/egress suitable for build-to-suit development.

View details

B-1 Commercial Development Land

3671 James Sanders Blvd., Paducah, KY 42001

$385,000

1.37 AC lot

B-1 commercial land with utilities in the City, positioned near a high-visibility corner for flexible development options.

View details

Level Commercial Development Lot

2549 New Holt Road, Paducah, KY 42001

$265,000

1.17 AC lot

1.17+/- acre level lot with a recorded plat showing approximately 3,675+/- SF buildable area.

View details

Cape Girardeau County, MO Office Buildings Market Trends and Statistics

Explore 7 office buildings for sale in Cape Girardeau County, MO, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 42,319 square feet of properties for sale, with an estimated market value of $2,929,700.

Sale prices for office properties in Cape Girardeau County, MO start at $239,900, averaging $488,283, and reaching up to $899,900 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.