Cape Girardeau County, MO Office buildings for sale

$1,690,000

15,831 SF

Renovated Mid-Century Office Building

429 N Broadview Street, Cape Girardeau, MO 63701

Renovated 1960s office building with event space, overhead doors, and gated rear parking for flexible operations.

Mid‑century modern commercial building originally constructed for the Teamsters in 1962
Approximately 10,000 SF on the main level with private offices, conference rooms, and an executive office with private bathroom
Event and gathering space with a full bar and projection screen for meetings, presentations, and training
Concrete and steel frame construction with brick exterior and forced air heat plus central air
4 overhead doors, 8 indoor parking spaces, and 55+ exterior parking spaces

Updated: Jun 5

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Fully Furnished Two-Level Office Building

$284,900

3,210 SF

Fully Furnished Two-Level Office Building

902 E Jackson Boulevard, Jackson, MO 63755

Move-in ready office building with separate entrances and multiple private offices on two levels for flexible use.

Fully furnished, move‑in ready professional office building suitable for various businesses.
Opportunity to own your workspace and generate income by leasing the second level.
Excellent visibility on E. Jackson Blvd., providing easy client access.
Two levels: Main level with reception, 4 offices, 2 conference rooms; Lower level with separate entrance, reception, 4 offices, breakroom.
Strategic investment: Own instead of rent, offset mortgage with lease income, expand later, or lease both levels.

Updated: Jun 11

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Renovated Commercial Building in Cape Girardeau

$239,900

2,937 SF

Renovated Commercial Building in Cape Girardeau

Renovated commercial building with high visibility in a prime location.

230 N Sprigg Street, Cape Girardeau, MO 63701

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$350,000

4,000 SF

Updated Office Building For Sale

Well-maintained office building with high visibility and ample parking.

824 Independence Street, Cape Girardeau, MO 63703

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$500,000

7,140 SF

Leased Office Building For Sale

Two-story office building with 21 units and parking.

2711 Thomas Drive, Cape Girardeau, MO 63701

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$815,000

9,857 SF

Two-Level Office Building For Sale

9,857 SF office building with multiple offices and restrooms.

10 Doctors Park, Cape Girardeau, MO 63703

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$239,900

2,937 SF

Renovated Commercial Building on Sprigg

Renovated commercial space with high visibility and income potential.

230 N Sprigg Street, Cape Girardeau, MO 63701

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$899,900

13,694 SF

Downtown Office Building For Sale

13,694 SF office building in historic downtown Cape Girardeau.

18 N. Main, Cape Girardeau, MO 63701

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Contact for pricing

6.78 Acres

Professional Office Complex For Sale

Professional office complex with parking near I-55, hotels, restaurants.

240-276 S. Mount Auburn Road, Cape Girardeau, MO 63703

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$899,900

13,694 SF

13,694 SF Single-Level Office Building

Single-level office building suitable for various uses and businesses.

18 Main St, Cape Girardeau, MO 63701

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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 10 Active listings in Cape Girardeau County, MO, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$144,000

1.01 Acres

Commercial Land on Highway 61

Commercial land on high-traffic route near Sikeston Industrial Park.

103 Grove Estates, Sikeston, MO 63801

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$972,000

1,092 SF

Prime Commercial Land, Perryville, MO

0.94 acre commercial land with high traffic and development potential.

1324 W Saint Joseph Street, Perryville, MO 63775

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$385,000

1.37 Acres

B-1 Commercial Development Land

B-1 commercial land with utilities in the City, positioned near a high-visibility corner for flexible development options.

3671 James Sanders Blvd., Paducah, KY 42001

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$265,000

1.17 Acres

Level Commercial Development Lot

1.17+/- acre level lot with a recorded plat showing approximately 3,675+/- SF buildable area.

2549 New Holt Road, Paducah, KY 42001

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Cape Girardeau County, MO Office Buildings Investment Opportunities Market Analysis

Explore 10 office buildings for sale in Cape Girardeau County, MO, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 57,469 square feet of properties for sale, with an estimated market value of $4,129,500.

Sale prices for office properties in Cape Girardeau County, MO start at $184,900, averaging $516,187, and reaching up to $899,900 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.