La Crosse County, WI Commercial Real Estate for Sale

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136 properties
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Medical Office Space with Apartment
Updated: Sep 3
Medical Office Space with Apartment

2128-2130 State Road 16, La Crosse, WI 54601

$649,000
6,298 sqft 0.49 AC lot
6,298 SF medical office property on a 0.49‑acre site
Reported visibility to 34,000 vehicles per day
Existing clinic layout with several exam rooms and work areas
Upper‑level residential apartment included
Garage parking and large paved lot
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Office Building with Flexible Layout
Updated: Sep 21
Office Building with Flexible Layout

3437-3439 East Avenue S, La Crosse, WI 54601

$899,000
19,460 sqft 0.51 AC lot
Two‑address office property with separate HVAC and electrical systems
Concrete and steel construction on a 0.511‑acre parcel
8 bathrooms, conference rooms, offices, cubicle areas, and kitchen‑break room
2 furnaces and 2 CA's
Renovated in 1994 and 2007
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Mixed-Use Building with Patio
Mixed-Use Building with Patio

234 Leonard St N, West Salem, WI 54669

$595,000
3,561 sqft 0.34 AC lot

Open commercial layout with two bathrooms, outdoor gathering space, and on-site parking.

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Concrete-and-Steel Office Building
Concrete-and-Steel Office Building

3439 East Ave S, La Crosse, WI 54601

$899,000
9,730 sqft

Professional office property with multiple work areas, conference rooms, separate building systems, and parking surrounding the structure.

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Tavern Building with Additional Bar
Tavern Building with Additional Bar

318 Pearl St, La Crosse, WI 54601

$550,000
2,600 sqft 0.30 AC lot

The property includes commercial zoning and a transferable liquor license.

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Restored Retail Storefront
Restored Retail Storefront

1535 Commercial St, Bangor, WI 54614

$215,000
800 sqft 0.02 AC lot

Commercially zoned space with a full basement, restroom, closet, and rear entrance.

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Operating Restaurant Property
Operating Restaurant Property

1123 3rd St S, La Crosse, WI 54601

$485,000
1,700 sqft 0.20 AC lot

Commercially zoned restaurant with an established local customer base and ongoing operations.

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Freestanding Restaurant Property
Freestanding Restaurant Property

3055 State Road 16 -, La Crosse, WI 54601

$1,350,000
5,000 sqft 0.75 AC lot

A modified lease runs through February 2027, with the tenant covering expenses other than property taxes.

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Airport Industrial Warehouse with Drive-Through Doors
Airport Industrial Warehouse with Drive-Through Doors

2974 Airport Rd, La Crosse, WI 54603

$2,200,000
16,080 sqft 1.50 AC lot

Warehouse facility with multiple overhead doors in La Crosse’s Airport Industrial Park.

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Mixed-Use Building with Apartment
Mixed-Use Building with Apartment

154 Leonard Street S, West Salem, WI 54669

$225,000
1,650 sqft 0.09 AC lot

Commercial building with a rear one-bedroom apartment, transferable conditional use permit, basement storage, and parking behind the property.

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Flex Property with Industrial Zoning
Flex Property with Industrial Zoning

2320 Cunningham St, La Crosse, WI 54603

$1,150,000
9,100 sqft 0.86 AC lot

Two-building property with open interiors, overhead doors, and Heavy Industrial zoning.

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Marina with Rental Duplex
Marina with Rental Duplex

2700 15th St S, La Crosse, WI 54601

$849,900
1,700 sqft 14.20 AC lot

A 14.2-acre waterfront property combines boat slips with apartment, garage, and parking improvements.

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Storefront With Drive-Through
Storefront With Drive-Through

1817 Jackson St, La Crosse, WI 54601

$249,000
2,250 sqft 0.19 AC lot

Commercially zoned retail property with convenient parking and a drive-through configuration.

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Floral Storefront with Garage
Floral Storefront with Garage

310 Sand Lake Rd, Onalaska, WI 54650

$634,800
2,500 sqft

Established floral and gift business with inventory, delivery vehicle, and operating systems included.

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Flex Warehouse with Three Overhead Doors
Flex Warehouse with Three Overhead Doors

2729 George St, La Crosse, WI 54603

$400,000
2,400 sqft 0.16 AC lot

Well-maintained La Crosse flex warehouse with three electric overhead doors, two distinct work areas, and gas heat.

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Boutique Vineyard and Winery
Boutique Vineyard and Winery

234 Leonard St N, West Salem, WI 54669

$325,000
3,561 sqft 0.34 AC lot

Commercial hospitality and wine production operation offering 53 wine varieties.

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Downtown Tavern with Upper Bar
Downtown Tavern with Upper Bar

318 Pearl St, La Crosse, WI 54601

$550,000
2,600 sqft

Operating tavern with an additional upstairs bar area and transferable liquor license.

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Vineyard Winery with Event Space
Vineyard Winery with Event Space

234 Leonard St N, West Salem, WI 54669

$850,000
3,561 sqft 0.34 AC lot

Commercially zoned operation combines wine production, direct sales, food service, and intimate event hosting.

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Mixed-Use Building with Warehouse
Mixed-Use Building with Warehouse

1613 Chase St, La Crosse, WI 54601

$825,000
10,712 sqft

Office suites, heated warehouse space, and an upper-level four-bedroom apartment support multiple occupancy configurations.

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Office Suite with Work Area
Office Suite with Work Area

555 Braund St, Onalaska, WI 54650

Contact for pricing
2,800 sqft 0.78 AC lot

The layout includes a reception area, conference room, several private offices, and an adjoining work area.

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Restaurant Building with Parking
Restaurant Building with Parking

3055 State Road 16, La Crosse, WI 54601

$1,350,000
5,000 sqft

An existing modified lease extends through February 2027, with the tenant covering expenses other than property taxes.

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Office Building with Private Offices
Office Building with Private Offices

2600 Ward Ave, La Crosse, WI 54601

Contact for pricing
3,013 sqft 0.12 AC lot

The interior includes a reception area, open workspace, kitchenette, laundry room, and three restrooms.

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Historic Multi-Space Storefront Building
Historic Multi-Space Storefront Building

319 Main St, La Crosse, WI 54601

$1,500,000
28,500 sqft

Character-rich commercial property with multiple spaces in downtown La Crosse, surrounded by restaurants, businesses, and amenities.

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Mixed-Use Property with Bar
Mixed-Use Property with Bar

828 5th Ave S, La Crosse, WI 54601

$675,000
1,512 sqft 0.48 AC lot

The property combines an operating bar with three residential rental units across adjoining parcels.

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La Crosse County, WI Commercial Real Estate Market Trends and Statistics

Explore 136 commercial real estate for sale in La Crosse County, WI, showcased through 136 active listings on our real estate platform. These investment opportunities span a total of 3,145,165 square feet of properties for sale, with an estimated market value of $109,150,386.

Sale prices for business properties in La Crosse County, WI start at $125,000, averaging $1,186,417, and reaching up to $8,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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