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    La Crosse, WI Retail Space for Sale

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    Milwaukee, WI Madison, WI Green Bay, WI
    Versatile Downtown La Crosse Property
    $699,999
    7,400 SF

    Versatile Downtown La Crosse Property

    422 Main St, La Crosse, WI 54601

    Historic property with event venue, office, and rental income.

    • Prime downtown La Crosse location, steps from restaurants, nightlife, and the riverfront.
    • Proven income‑generating luxury apartment (short‑term rental) at 424 Main.
    • Versatile space suitable for event venue or reimagining for other uses.
    • Includes stage, lighting, bar, and kitchen equipment (negotiable).
    • Corner office suite included.
    Updated: Dec 1, 2025
    View details
    Based on your search, we've compiled 272 Potential Opportunities for your consideration. Besides 1 Active listings in La Crosse, WI, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 265 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Freestanding Retail Building in Onalaska
    $2,643,000
    15,748 SF

    Freestanding Retail Building in Onalaska

    Freestanding 15,768 SF retail building in Onalaska, Wisconsin.

    1231 Crossing Meadows Drive, Onalaska, WI 54650
    View details
    Established Laundromat Business Opportunity
    $149,900
    1,500 SF

    Established Laundromat Business Opportunity

    Successful laundromat business for sale in downtown location.

    118 W Grove Street, Caledonia, MN 55921
    View details
    Downtown Caledonia Retail Opportunity
    $149,900
    1,500 SF

    Downtown Caledonia Retail Opportunity

    Long-running laundromat business with recent updates on a large lot.

    118 W Grove St, Caledonia, MN 55921
    View details
    Prime Commercial Land Opportunity
    Contact for pricing

    Prime Commercial Land Opportunity

    Strategically located land near Valley View Mall for sale/lease.

    3900 WI-16, Onalaska, WI 54650
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Growing Corridor
    $1,795,000
    2.07 Acres

    Prime Land in Growing Corridor

    2.07 acres of PUD-zoned land on State Hwy 207.

    3229 State Road 207, Elkton, FL 32033
    View details
    Commercial Land on Busy Roadway
    $750,000
    0.72 Acres

    Commercial Land on Busy Roadway

    Prime commercial land with high visibility and development potential.

    5355 TURNPIKE FEEDER ROAD, Fort Pierce, FL 34945
    View details

    Explore Off-Market Properties in La Crosse, WI

    Consider similar Off-Market properties in La Crosse, WI. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    512 8th S St

    512 8th S St

    RETAIL STORES (PERSONAL SERVICES) • 855 SF
    Value Estimation by Request
    512 8th S St, La Crosse, WI 54601-4637
    View details
    55 Copeland Ave

    55 Copeland Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,089 SF
    Value Estimation
    $1,235,000
    55 Copeland Ave, La Crosse, WI 54603-3402
    View details
    117 6th N St

    117 6th N St

    RETAIL STORES (PERSONAL SERVICES) • 4,550 SF
    Value Estimation by Request
    117 6th N St, La Crosse, WI 54601-3366
    View details
    3900 State Rd 16

    3900 State Rd 16

    RETAIL STORES (PERSONAL SERVICES) • 9.86 Acres
    Value Estimation
    $2,505,000
    3900 State Rd 16, La Crosse, WI 54601-1808
    View details
    317 Division St

    317 Division St

    RETAIL STORES (PERSONAL SERVICES) • 1,800 SF
    Value Estimation by Request
    317 Division St, La Crosse, WI 54601-4427
    View details
    724 Moore St

    724 Moore St

    RETAIL STORES (PERSONAL SERVICES) • 0.83 Acres
    Value Estimation by Request
    724 Moore St, La Crosse, WI 54603-2001
    View details
    3960 Mormon Coulee Rd

    3960 Mormon Coulee Rd

    STORE, RETAIL OUTLET • 2.01 Acres
    Value Estimation by Request
    3960 Mormon Coulee Rd, La Crosse, WI 54601-7916
    View details
    1223 Caledonia St

    1223 Caledonia St

    STORE, RETAIL OUTLET • 0.24 Acres
    Value Estimation by Request
    1223 Caledonia St, La Crosse, WI 54603-2514
    View details
    1222 Caledonia St

    1222 Caledonia St

    STORE, RETAIL OUTLET • 3,871 SF
    Value Estimation by Request
    1222 Caledonia St, La Crosse, WI 54603-2513
    View details
    1834 George St

    1834 George St

    RETAIL STORES (PERSONAL SERVICES) • 1,540 SF
    Value Estimation by Request
    1834 George St, La Crosse, WI 54603-2117
    View details
    113 2nd S St

    113 2nd S St

    STORE, RETAIL OUTLET • 0.13 Acres
    Value Estimation
    $1,375,000
    113 2nd S St, La Crosse, WI 54601-3206
    View details
    2127 Ss Ave

    2127 Ss Ave

    RETAIL STORES (PERSONAL SERVICES) • 0.49 Acres
    Value Estimation by Request
    2127 Ss Ave, La Crosse, WI 54601-6258
    View details
    122 5th S Ave

    122 5th S Ave

    RETAIL STORES (PERSONAL SERVICES) • 1,460 SF
    Value Estimation by Request
    122 5th S Ave, La Crosse, WI 54601-4008
    View details
    1353 Caledonia St

    1353 Caledonia St

    STORE, RETAIL OUTLET • 0.16 Acres
    Value Estimation by Request
    1353 Caledonia St, La Crosse, WI 54603-2412
    View details
    1301 Avon St

    1301 Avon St

    STORE, RETAIL OUTLET • 0.11 Acres
    Value Estimation by Request
    1301 Avon St, La Crosse, WI 54603
    View details
    506 Copeland Ave

    506 Copeland Ave

    RETAIL STORES (PERSONAL SERVICES) • 1,770 SF
    Value Estimation by Request
    506 Copeland Ave, La Crosse, WI 54603
    View details
    1704 George St

    1704 George St

    STORE, RETAIL OUTLET • 0.39 Acres
    Value Estimation by Request
    1704 George St, La Crosse, WI 54603-2150
    View details
    1022 La Crosse St

    1022 La Crosse St

    STORE, RETAIL OUTLET • 0.22 Acres
    Value Estimation
    $580,000
    1022 La Crosse St, La Crosse, WI 54601-3418
    View details
    3700 State Rd 16

    3700 State Rd 16

    RETAIL STORES (PERSONAL SERVICES) • 2.26 Acres
    Value Estimation
    $10,115,000
    3700 State Rd 16, La Crosse, WI 54601-1806
    View details
    307 Pearl St

    307 Pearl St

    STORE, RETAIL OUTLET • 0.07 Acres
    Value Estimation by Request
    307 Pearl St, La Crosse, WI 54601-3249
    View details
    821 Clinton St

    821 Clinton St

    RETAIL STORES (PERSONAL SERVICES) • 873 SF
    Value Estimation by Request
    821 Clinton St, La Crosse, WI 54603-2474
    View details
    2025 Denton St

    2025 Denton St

    RETAIL STORES (PERSONAL SERVICES) • 758 SF
    Value Estimation by Request
    2025 Denton St, La Crosse, WI 54601-5818
    View details
    115 4th S St

    115 4th S St

    STORE, RETAIL OUTLET • 0.06 Acres
    Value Estimation by Request
    115 4th S St, La Crosse, WI 54601-3257
    View details

    La Crosse, WI Retail Space Investment Opportunities Market Analysis

    Explore 266 retail space for sale in La Crosse, WI on our real estate platform. These investment opportunities span a total of 9,740,322 square feet of properties for sale, with an estimated market value of $126,319,999.

    Sale prices for retail space in La Crosse, WI start at $65,000, averaging $601,523, and reaching up to $16,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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