Sign Up Successful!
You now have access to more from Realmo!
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Salem County, VA Commercial Real Estate for Sale

    231 results
    List
    Map
    Updated Building with High-End Finishes
    $2,100,000
    0.05 Acres

    Updated Building with High-End Finishes

    109 Campbell Ave SW, Roanoke, VA 24011

    Extensively updated building with high-end materials and great views.

    • Extensively updated with high‑end materials, move‑in ready
    • Two residential units, each with 2 bedrooms and high‑end appliances including Wolf gas stove, Cove dishwasher, and Sub‑Zero fridge
    • Former art gallery space on entry level with full kitchen
    • Complete renovation: new windows, flooring, HVAC, electrical, and plumbing
    • Large primary suites with walk‑in showers and closets in both residential units
    Updated: Jan 5
    View details
    Franklin Road Office/Retail Opportunity
    $1,350,000
    1.00 Acre

    Franklin Road Office/Retail Opportunity

    4040 Franklin Rd SW, Roanoke, VA 24014

    Prime commercial land on Franklin Road with high traffic volume.

    • High‑visibility location on Franklin Road/Route 220 with a VDOT daily traffic count of 32,000.
    • Suitable for office, medical, or retail use.
    • Includes 2 parcels totaling 1 acre.
    • Recently remodeled (less than 3 years ago).
    • Loading docks available.
    Updated: Oct 5, 2025
    View details
    Retail Opportunity in North Roanoke
    $499,000
    0.56 Acres

    Retail Opportunity in North Roanoke

    Retail property with high visibility in North Roanoke, Virginia.

    5623 Williamson Rd, Roanoke, VA 24012
    View details
    Roanoke Investment Opportunity
    $545,000
    0.31 Acres

    Roanoke Investment Opportunity

    Well-maintained commercial building leased to the Commonwealth of Virginia.

    414 9Th St SE, Roanoke, VA 24013
    View details
    Versatile Retail and Industrial Property
    $349,000
    0.19 Acres

    Versatile Retail and Industrial Property

    Retail and industrial property in high-traffic location on Williamson Rd.

    1408 Williamson Rd NE, Roanoke, VA 24012
    View details
    Roanoke Office Building For Sale
    $750,000
    0.63 Acres

    Roanoke Office Building For Sale

    Traditional office building with on-site parking and corner location.

    4533 Brambleton Ave, Roanoke, VA 24018
    View details
    Roanoke Retail Building For Sale
    $315,000
    0.19 Acres

    Roanoke Retail Building For Sale

    Well-maintained commercial building in high-traffic Roanoke location.

    3118 Williamson Rd NW, Roanoke, VA 24012
    View details
    Roanoke Office/Retail Building For Sale
    $650,000
    0.30 Acres

    Roanoke Office/Retail Building For Sale

    Office building with subdivision potential and ample parking.

    356 Campbell Ave SW, Roanoke, VA 24016
    View details
    Retail Building on Williamson Road
    Pending
    $1,375,000
    8,772 SF

    Retail Building on Williamson Road

    NNN leased retail building with strong tenant in Roanoke, VA.

    3607 Williamson Rd, Roanoke, VA 24012
    View details
    Historic Horton Building For Sale
    $2,875,000
    0.20 Acres

    Historic Horton Building For Sale

    Landmark Roanoke building blending early-20th-century craftsmanship and modern functionality.

    302 1St St SW, Roanoke, VA 24011
    View details
    Downtown Roanoke Investment Opportunity
    $875,000
    0.05 Acres

    Downtown Roanoke Investment Opportunity

    Two-unit building in vibrant downtown Roanoke with retail and residential.

    22 Campbell Ave SE, Roanoke, VA 24011
    View details
    Commercial Property on Williamson Road
    $550,000
    0.79 Acres

    Commercial Property on Williamson Road

    Two commercial buildings with high potential on a 0.79-acre lot.

    2211 Williamson Rd NE, Roanoke, VA 24012
    View details
    Well-Maintained Condo Near Greenway
    $208,500

    Well-Maintained Condo Near Greenway

    2-bedroom, 2-bath condo near hospital, shopping, and Greenway.

    2513 Gatehouse Ln, Salem, VA 24153
    View details
    Roanoke Office/Retail Ready For Business
    $476,850
    0.32 Acres

    Roanoke Office/Retail Ready For Business

    Well-appointed, updated office/retail space near interstate, airport, and downtown.

    624-626 Abney Rd, Roanoke, VA 24012
    View details
    Income Producing Duplex For Sale
    $195,000
    1,760 SF

    Income Producing Duplex For Sale

    Well-maintained duplex with two 2-bedroom units and off-street parking.

    3122 Garden City Blvd SE, Roanoke, VA 24014
    View details
    Grandin Village Retail Opportunity
    $424,950
    2,900 SF

    Grandin Village Retail Opportunity

    Commercial property in Roanoke's Grandin Village, heavy traffic area.

    1911 Memorial Ave SW, Roanoke, VA 24015
    View details
    Roanoke Office Building with Views
    $1,300,000
    10,129 SF

    Roanoke Office Building with Views

    10,129 SF office building with valley views for sale.

    7851-7857 Enon Dr, Roanoke, VA 24019
    View details
    Multi-Tenant Office Building For Sale
    $1,425,000
    7,416 SF

    Multi-Tenant Office Building For Sale

    7,500 SF multi-tenant office building on 1.44 acres.

    1618 W Main St, Salem, VA 24153
    View details
    High-Tech Manufacturing and Warehouse Facility
    $10,750,000
    146,852 SF

    High-Tech Manufacturing and Warehouse Facility

    Expandable manufacturing, office, and warehouse facility near I-581 and I-81.

    2797 Frontage Rd - NW, Roanoke, VA
    View details
    Self-Service Car Wash Investment
    $235,000

    Self-Service Car Wash Investment

    Six-bay car wash with high visibility and traffic count.

    4101 Plantation Rd NE | Roanoke, Roanoke, VA 24012
    View details
    Industrial Property with Two Buildings
    $1,295,000
    9,200 SF

    Industrial Property with Two Buildings

    Two industrial buildings totaling 9,200 SF on 1.4 acres.

    3718 Garman Rd, Salem, VA 24153
    View details
    Office Condo in McVitty Center
    $205,000
    1,205 SF

    Office Condo in McVitty Center

    Office condo with reception, offices, restrooms, and kitchenette for sale.

    2774 Electric Rd Southwest | Roanoke, Roanoke, VA 24014
    View details
    Multi-Tenant Professional Business Center
    $1,750,000
    12,000 SF

    Multi-Tenant Professional Business Center

    12,000 SF multi-tenant professional center with strong rental history.

    192 Summerfield Ct, Roanoke, VA 24019
    View details
    Renovated Commercial Building in Roanoke
    $319,000
    1,200 SF

    Renovated Commercial Building in Roanoke

    Updated 1200 sq ft commercial space in Old Southwest Roanoke.

    708 5Th St SW, Roanoke, VA 24016
    View details

    Salem County, VA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 941 commercial real estate investment opportunities in Salem County, VA with 231 listings featured on our commercial real estate marketplace. The current inventory includes 41,155,831 square feet of properties with an estimated value of $391,579,802.

    Estimated prices for commercial real estate in Salem County, VA begin at $35,000, with an average of $593,302 and extend to $13,755,000.

    In Salem County, VA, current investment values show:

    • Other commercial real estate positioned at $480,235
    • Industrial properties measuring $833,277
    • Other industrial properties assessed at $1,035,491
    • Other warehouses calculated at $575,652
    List
    Map

    Commercial real estate by market

    Browse Commercial real estate for Sale Near Salem, VA

    Popular Searches in Salem

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.