Mixed-Use

Salem County, VA Mixed-use Properties for Sale

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Downtown Mixed-Use Building with Retail
Updated: Nov 13, 2025
Downtown Mixed-Use Building with Retail

22 Campbell Ave SE, Roanoke, VA 24011

$799,000
0.05 AC lot
Prime Downtown Roanoke location with high visibility.
Two‑unit building: street‑level retail and a renovated 2bd/2bth residence offering investment potential.
Renovated second‑floor residence (2021) featuring recessed lighting, granite, hardwoods, and en suite bathrooms.
Potential to develop a rooftop deck.
Proximity to iconic attractions like Center In The Square and the Farmers Market.
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Roanoke Executive Park Investment Opportunity
Updated: Mar 3
Roanoke Executive Park Investment Opportunity

5306 Peters Creek Rd, Roanoke, VA 24019

$7,325,000
54,000 sqft 5.10 AC lot
Six buildings totaling ±54,000 SF on ±5.1 acres in a campus setting
Located on Peters Creek Road with high visibility, strong traffic counts, and easy access to I‑581 and I‑81
Zoned C‑2 (General Commercial) allowing for diverse commercial uses (office, medical, retail, service)
Flexible user and investment potential with multi‑tenant or single‑building occupancy options
Ample on‑site parking and strong internal circulation
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Peters Creek Road Commercial Property
Peters Creek Road Commercial Property

3783 Peters Creek Rd, Roanoke, VA 24018

$1,300,000
14,600 sqft 1.27 AC lot

Commercial property with visibility and access on 1.27 acres.

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Mixed-Use Building with Leased Units
Mixed-Use Building with Leased Units

1011 2nd St SW, Roanoke, VA 24016

$415,000
3,294 sqft

Mixed-use building with office space and two leased apartments.

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Green Ridge Center For Sale
Green Ridge Center For Sale

2350 Peters Crk Rd NW, Roanoke, VA 24017

$1,649,000
13,908 sqft

Mixed-use property with retail and office spaces available for sale.

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Downtown Roanoke Mixed-Use Opportunity
Downtown Roanoke Mixed-Use Opportunity

21 Church Ave SW, Roanoke, VA

$349,950
4,474 sqft 0.05 AC lot

Former florist building with live-work potential in downtown Roanoke.

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Prime Commercial Development Opportunity
Prime Commercial Development Opportunity

4402 Old Rocky Mt Rd, Roanoke, VA 24014

$490,000
4.36 AC lot

4.36 acres of mixed-use land for commercial development.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 7 Active listings in Salem County, VA, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Mixed-Use Development Lot
Mixed-Use Development Lot

Church Ave SE, Roanoke, VA 24013

Contact for pricing
0.11 AC lot

Small lot with water and sewer availability for flexible mixed-use development in Roanoke.

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Westlake Commercial Property for Sale
Westlake Commercial Property for Sale

Booker T Washington Hwy lot: 3, Hardy, VA 24101

$2,200,000
7.75 AC lot

7.75 acres of prime commercial real estate in Westlake.

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Commercial Land in Moneta, VA
Commercial Land in Moneta, VA

LOT C-26 Booker T. Washington Highway, Moneta, VA 24121

$225,000
1.37 AC lot

Commercial land available in Lakewatch Plantation, Moneta, Virginia.

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Commercial Land with Road Frontage
Commercial Land with Road Frontage

15093 A Moneta Rd, Moneta, VA 24121

$2,499,000
56.00 AC lot

56-acre tract with mixed-use zoning potential and utilities available, offering strong exposure along Route 122.

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Salem County, VA Mixed-Use Properties Market Trends and Statistics

Explore 7 mixed-use properties for sale in Salem County, VA, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 90,276 square feet of properties for sale, with an estimated market value of $11,038,950.

Sale prices for multi use buildings in Salem County, VA start at $349,950, averaging $2,207,790, and reaching up to $7,325,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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