Salem County, VA Commercial Real Estate for Sale

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189 properties
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Corner-Lot Office Building
Corner-Lot Office Building

1540 Apperson Dr, Salem, VA 24153

$340,000
2,765 sqft 0.38 AC lot

HBD-zoned office property with hardwood floors, parking, and a prominent corner position.

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Self-Storage Facility with Secure Access
Self-Storage Facility with Secure Access

2280 Salem Industrial Dr, Salem, VA 24153

$6,050,000
44,008 sqft

257-unit facility with controlled entry, surveillance, security lighting, and an on-site management office.

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Historic Roanoke Retail/Restaurant Opportunity
Historic Roanoke Retail/Restaurant Opportunity

19 Salem Ave SE |, Roanoke, VA 24011

$779,000
4,000 sqft

Renovated 4,000 SF property in Roanoke's historic market district.

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1.2 Acre Commercial Site
1.2 Acre Commercial Site

5436 Franklin Road, Roanoke, VA 24014

$595,000
1,800 sqft 1.20 AC lot

Commercial land near new Wal-Mart with road frontage.

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Childcare Center For Sale
Childcare Center For Sale

5220 Starkey Rd, Roanoke, VA 24018

$1,879,862
3,088 sqft

Childcare Network offered for sale with 7.25% noted in the offering remarks.

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Flexible Warehouse and Showroom Building
Flexible Warehouse and Showroom Building

6704 Williamson Rd, Roanoke, VA 24019

$1,099,000
11,000 sqft 0.52 AC lot

A flexible C-2 zoned building with showroom, offices, storage, and rear warehouse roll-up door access.

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Mixed-Use Retail and Office Building
Mixed-Use Retail and Office Building

2302 Winthrop Ave Sw, Roanoke, VA 24015

$475,000
1,964 sqft

One-story, handicap-accessible mixed-use building with 2 bathrooms, new roof, and a tankless water heater.

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Retail and Showroom Building
Retail and Showroom Building

6712 Williamson Rd, Roanoke, VA 24019

$549,000
5,850 sqft 0.49 AC lot

Flexible retail or showroom building with open layout, multiple restrooms, and on-site parking, zoned C-2.

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Mixed-Use Property with End-Cap Space
Mixed-Use Property with End-Cap Space

1727 Peters Creek Rd Nw, Roanoke, VA 24017

$875,000
1.15 AC lot

Eight-unit commercial property combining retail, office, and flex space with two-street access and a renovated vacant suite.

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Multi-Tenant Office Building For Sale
Multi-Tenant Office Building For Sale

1618 W Main St, Salem, VA 24153

$1,425,000
7,416 sqft

7,500 SF multi-tenant office building on 1.44 acres.

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Fully Leased Office Building
Fully Leased Office Building

1225 Maple Ave SW, Roanoke, VA 24016

Contact for pricing
4,601 sqft

Finished professional space in a neighborhood setting with on-site and on-street parking.

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Level Commercial Land Parcel
Level Commercial Land Parcel

5378 Franklin Road, Roanoke, VA 24014

$850,000
307,533 sqft

Level parcel with a gravel road approach and on-site utility access, including an existing billboard on a year-to-year lease.

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Industrial Property with Two Buildings
Industrial Property with Two Buildings

3718 Garman Rd |, Salem, VA 24153

$1,295,000
9,200 sqft

Two industrial buildings totaling 9,200 SF on 1.4 acres.

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Six-Story Commercial Building in Roanoke
Six-Story Commercial Building in Roanoke

302 S. Jefferson St |, Roanoke, VA 24011

$2,600,000
32,445 sqft

Six-story commercial building in downtown Roanoke with redevelopment opportunities.

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Development Ready Land Near Retail
Development Ready Land Near Retail

0 Crumpacker Dr, Roanoke, VA 24019

$1,999,950
10 sqft 10.49 AC lot

10.49 acres of flat, development-ready land near major retailers.

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Downtown Roanoke Office Building
Downtown Roanoke Office Building

34 Campbell Avenue Southwest |, Roanoke, VA 24011

$4,250,000
102,580 sqft

Five-story office building in downtown Roanoke with stable tenant mix.

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Freestanding Absolute NNN CVS Property
Freestanding Absolute NNN CVS Property

7515 Williamson Road, Roanoke, VA 24019

Contact for pricing
11,985 sqft

Absolute NNN-leased freestanding CVS building with over 20 years of tenant operation and more than four years of firm term remaining.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

22 Campbell Ave SE, Roanoke, VA 24011

Contact for pricing
4,400 sqft

Central, high-traffic location with first-floor retail occupancy starting September 1, 2026.

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Warehouse with Roll-Up Door
Warehouse with Roll-Up Door

2821 West Main Street, Salem, VA 24153

$795,000
0.96 AC lot

Single warehouse built in 2011 with on-site parking and an 8-foot roll-up door.

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Level Commercial Corner Lot
Level Commercial Corner Lot

3509 Peters Creek Road, Roanoke, VA 24019

$115,000
18,730 sqft

Level corner parcel with prior approval for a two-story office building.

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Corner Commercial Development Land
Corner Commercial Development Land

909 13th St, Roanoke, VA 24013

$795,000
2.47 AC lot

A level, corner parcel with utilities available and strong visibility at a traffic-light intersection for commercial development.

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15.72 Acres Commercial Land
15.72 Acres Commercial Land

0 Valley Gateway BLVD, Roanoke, VA 24019

$4,500,000
15 sqft 15.72 AC lot

Flat, development-ready commercial land near Kroger anchored shopping center.

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Medical Office with Exam Rooms
Medical Office with Exam Rooms

1934 BRAEBURN DR, Salem, VA 24153

Contact for pricing
1,443 sqft

Established clinical layout with reception, multiple treatment rooms, private offices, restrooms, and parking availability.

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Flat Graded Retail Development Site
Flat Graded Retail Development Site

1930 Valley View Boulevard NW, Roanoke, VA 24012

$1,350,000
1.02 AC lot

Flat, graded pad with paved access and on-site parking, suitable for inline retail and potential drive-through/QSR use.

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