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    Salem County, VA Medical Office Space for Lease

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    Richmond, VA Virginia Beach, VA Alexandria, VA
    13 results
    Bank-Converted Office Building
    $15 SF/Yr
    6,631 SF

    Bank-Converted Office Building

    301 McClanahan Street SW, Roanoke, VA 24014

    Converted for office or medical use with renovated second-floor space and on-site parking for convenient access.

    • Former Wells Fargo bank branch with ~3,300 SF on two floors (total 6,631 SF).
    • Second‑floor office space was recently renovated and is ready for use.
    • First floor includes office space and a drive‑thru option if desired.
    • 34 on‑site parking spaces for employees and visitors.
    • Multiple ingress/egress points for access flexibility.
    Updated: Jun 1
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    Brambleton Avenue Commercial Space Available
    $22 SF/Yr
    1,700 SF

    Brambleton Avenue Commercial Space Available

    5002 Brambleton Ave, Roanoke, VA 24018

    1,700 SF space suitable for medical, office, or retail.

    • High‑traffic location on Brambleton Ave with 26,000 vehicles per day
    • Versatile 1,700 SF space suitable for medical, professional office, or retail use
    • Previously a dental office, featuring 4 operatories, reception area, 2 bathrooms, office, sterilization area, and break room
    • Close proximity to the new Publix site and established neighborhoods
    • Located in a desirable area of southwest county
    Updated: Mar 6
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    Prime Commercial Space in Roanoke
    $12 SF/Yr
    10,923 SF

    Prime Commercial Space in Roanoke

    Modern, versatile office space in Roanoke's Innovation Corridor.

    2727 Franklin Rd, Roanoke, VA
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    Retail Space Near Valley View
    Contact for pricing
    6,900 SF

    Retail Space Near Valley View

    Endcap space for sale or lease near Valley View Mall.

    1920 Valley View Blvd NW, Roanoke, VA 24012
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    Office Space Off Interstate
    $12 SF/Yr

    Office Space Off Interstate

    Office leasing opportunity with convenient access just off 581 for a range of professional uses.

    1125 South Jefferson St., Roanoke, VA 24016
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    Roanoke Office and Medical Space
    $16 SF/Yr
    1,152 SF

    Roanoke Office and Medical Space

    Office and medical space in Roanoke's growth corridor.

    1315 2nd St SW, Roanoke, VA
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    First Floor Office Suite
    $14 SF/Yr
    3,000 SF

    First Floor Office Suite

    Office suite for rent with high visibility and ample parking.

    5304 Indian Grave Rd, Roanoke, VA
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    New Class A Office Space
    Contact for pricing
    6,500 SF

    New Class A Office Space

    Newly constructed medical/professional office space for lease in Roanoke County.

    3090 Electric Rd, Roanoke, VA
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    Office Space in Prime Location
    $15 SF/Yr
    2,023 SF

    Office Space in Prime Location

    Ready-to-use office suites in a demographically affluent Roanoke neighborhood.

    3241 Electric Rd, Roanoke, VA
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    Roanoke Office Space For Lease
    $11 SF/Yr
    1,912 SF

    Roanoke Office Space For Lease

    Ready-to-use office suites in a well-located Roanoke office park.

    3247 Electric Rd, Roanoke, VA
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    Professional Office Space For Lease
    $12 SF/Yr
    957 SF

    Professional Office Space For Lease

    Customizable office suites in affluent Roanoke neighborhood, recently renovated.

    3243 Electric Rd, Roanoke, VA
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    Medical/Professional Office Space Available
    $19 SF/Yr
    3,000 SF

    Medical/Professional Office Space Available

    3,000 SF medical/professional office space for lease.

    375 Hershberger Rd, Roanoke, VA
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    Office or Medical Space Available
    $17 SF/Yr
    1,800 SF

    Office or Medical Space Available

    Office or medical space for lease in Roanoke, Virginia.

    4633 Brambleton Ave, Roanoke, VA
    View details
    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 13 Active listings in Salem County, VA, we suggest exploring alternatives. Similar 10 Properties for Sales.

    Similar Spaces for Sale in Salem County, VA

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Brick Office Building with Parking
    $195,000
    0.24 Acres
    Brick Office Building with Parking

    Brick building with office-ready interior, small restrooms, and on-site surface parking for a range of service or office uses.

    824 Iowa St, Salem, VA 24153

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    Salem, VA Office Building For Sale
    $995,000
    5,163 SF
    Salem, VA Office Building For Sale

    Multi-tenant office building in Salem's Electric Road corridor.

    1101 Electric Rd, Salem, VA 24153

    View details
    Multi-Tenant Office Building For Sale
    $1,425,000
    7,416 SF
    Multi-Tenant Office Building For Sale

    7,500 SF multi-tenant office building on 1.44 acres.

    1618 W Main St, Salem, VA 24153

    View details
    Medical/Office Building in Roanoke County
    $1,250,000
    5,678 SF
    Medical/Office Building in Roanoke County

    5,678 SF medical/office building on 1.15 acre site.

    5303 Indian Grave Rd, Roanoke, VA

    View details
    Medical/Office Building Near Valley View
    Contact for pricing
    60,055 SF
    Medical/Office Building Near Valley View

    60,055 RSF medical/office building adjacent to Valley View Mall.

    4910 Valley View Boulevard Northwest, Roanoke, VA 24012

    View details
    South Roanoke Office/Medical Opportunity
    $1,750,000
    6,631 SF
    South Roanoke Office/Medical Opportunity

    Office or medical building near Carilion Roanoke Memorial Hospital.

    301 McClanahan St - SW, Roanoke, VA

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    South Roanoke Office/Medical Building For Sale
    $1,750,000
    6,631 SF
    South Roanoke Office/Medical Building For Sale

    Office or medical building in South Roanoke with parking.

    301 McClanahan St SW, Roanoke, VA 24014

    View details
    Medical Office Building For Rent
    $1,150,000
    3,391 SF
    Medical Office Building For Rent

    Southwest County medical office building with two suites available.

    5100-5104 Bernard Dr, Roanoke, VA

    View details
    Roanoke Office Building with Views
    $1,350,000
    10,129 SF
    Roanoke Office Building with Views

    10,129 SF office building with valley views for sale.

    7851-7857 Enon Dr, Roanoke, VA

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    Multi-Tenant Office Building For Sale
    $1,425,000
    7,416 SF
    Multi-Tenant Office Building For Sale

    7,500 SF multi-tenant office building on 1.44 acres.

    1618 W Main St, Salem, VA 24153

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details
    Prime Lexington Outlot Opportunity
    Contact for pricing

    Prime Lexington Outlot Opportunity

    Outlot for ground lease or build-to-suit in South Lexington.

    3330 Partner Place, Lexington, KY 40503
    View details
    Beaumont Centre Outparcel Opportunity
    Contact for pricing

    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

    3199 Beaumont Centre Circle, Lexington, KY 40513
    View details
    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF

    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756
    View details

    Salem County, VA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Salem County, VA with 13 listings featured on our commercial real estate exchange. The current inventory includes 33,098 square feet of properties with an estimated lease value of $154 SF/Yr.

    Estimated lease rates for Medical Office Space in Salem County, VA begin at $11 SF/Yr, with an average of $15 SF/Yr and extend to $22 SF/Yr.
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    Browse Medical Office Space for Lease Near Salem, VA

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