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    Pickens County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    107 results
    Pickens Office Investment Opportunity
    $350,000
    0.16 Acres

    Pickens Office Investment Opportunity

    113 Court Street, Pickens, SC 29671

    Commercial office building near Pickens County Court House.

    • Prime commercial location next to the Pickens County Court House.
    • Two rental units provide additional income, with one unit currently leased through June 2027 at $750/month.
    • Unique architectural features including soaring wood ceilings, solid wood beams, brick wall accents & flooring, and a double brick fireplace.
    • Flexible floor plan with multiple offices, meeting room, conference room, kitchenette, reception area, and open work areas.
    • Private brick courtyard provides natural light and an appealing outdoor space.
    Updated: Apr 14
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    Multi-Use Property in Easley, SC
    $165,000
    0.34 Acres

    Multi-Use Property in Easley, SC

    612 W Main Street, Easley, SC 29640

    Versatile commercial and residential property near downtown Easley.

    • High‑visibility location less than a mile from downtown Easley and minutes from The Silos.
    • Offers both commercial and residential use potential.
    • Large, open space with a wood‑burning fireplace suitable for various business purposes.
    • Versatile layout with rooms adaptable as private offices, meeting spaces, or client areas.
    • Secluded room with updated lighting and fresh paint, ideal for a private office or executive suite.
    Updated: Apr 28
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    Easley Commercial Opportunity on Highway
    $249,900
    0.49 Acres

    Easley Commercial Opportunity on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640
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    Easley Commercial Property on Highway
    $249,900
    0.49 Acres

    Easley Commercial Property on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640
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    Retail Opportunity in Pickens, SC
    $350,000

    Retail Opportunity in Pickens, SC

    Retail space available for purchase in Pickens, South Carolina.

    131/133 W Main Street, Pickens, SC 29671
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    Prime Acreage in Pickens, SC
    $570,000
    1.55 Acres

    Prime Acreage in Pickens, SC

    Acreage in a rapidly growing area of Pickens County.

    106 Roberts Drive, Pickens, SC 29671
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    Commercial Land in Easley, SC
    $449,900
    0.50 Acres

    Commercial Land in Easley, SC

    Commercial land with investment potential in the heart of Easley.

    329 Prince Perry Road, Easley, SC 29640
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    Liberty, SC Commercial Site
    $374,000
    5.00 Acres

    Liberty, SC Commercial Site

    5-acre commercial site in Liberty, South Carolina.

    00 Ruhamah Road, Liberty, SC 29657
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    Easley Commercial Land Opportunity
    $52,500
    0.38 Acres

    Easley Commercial Land Opportunity

    0.38 acres of commercial land in a growing area.

    109 Franklin Square Way, Easley, SC 29642
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    Easley Commercial Land Opportunity
    $52,500
    0.38 Acres

    Easley Commercial Land Opportunity

    0.38 acres of commercial land in a growing area.

    109 Franklin Square Way, Easley, SC 29642
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    Liberty, SC Commercial Site
    $117,500
    3.00 Acres

    Liberty, SC Commercial Site

    3+ acre commercial site near Highway 123 in Liberty.

    00 Farmers Hill Road, Liberty, SC 29657
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    Easley Commercial Land For Sale
    $569,000
    5.70 Acres

    Easley Commercial Land For Sale

    5.7 acre commercial land available in Easley, South Carolina.

    533 Crest Drive, Easley, SC 29640
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    Prime Land in Pickens, SC
    $1,200,000
    3.24 Acres

    Prime Land in Pickens, SC

    3.24 acres in a rapidly growing area with development potential.

    2663 Gentry Memorial Highway, Pickens, SC 29671
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    Land Borders Southern Oaks Golf
    $999,900
    4.27 Acres

    Land Borders Southern Oaks Golf

    4.27 acres bordering golf course, ideal for homes or business.

    8426 81 N Highway, Easley, SC 29642
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    Land Borders Southern Oaks Golf
    $999,900
    4.27 Acres

    Land Borders Southern Oaks Golf

    4.27 acres bordering golf course, ideal for development.

    8426 81 N Highway, Easley, SC 29642
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    Easley Commercial Land Opportunity
    $275,000
    2.00 Acres

    Easley Commercial Land Opportunity

    2-acre commercial land with existing building, development potential.

    2625 Farrs Bridge Road, Easley, SC 29640
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    Downtown Easley Retail Opportunity
    Contact for pricing

    Downtown Easley Retail Opportunity

    2,000 SF retail space in downtown Easley, SC.

    106 N Pendleton Street, Easley, SC 29640
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    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Boulevard, Clemson, SC 29631
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    Easley Commercial Land For Sale
    $55,000
    0.39 Acres

    Easley Commercial Land For Sale

    0.39 acre commercial lot with road frontage in Easley, SC.

    315 Gentry Memorial Highway, Easley, SC 29640
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    Prime Development Site in Easley
    $1,615,000
    17.00 Acres

    Prime Development Site in Easley

    17+/- acres for development near Highway 123 in Easley, SC.

    00 Prince Perry Road, Easley, SC 29640
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    Easley Commercial Site For Sale
    $1,900,000
    17.22 Acres

    Easley Commercial Site For Sale

    17+ acre commercial site near Easley, SC.

    00 Cardinal Drive, Easley, SC 29642
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    Land with Mountain Views
    $255,000
    8.60 Acres

    Land with Mountain Views

    Land parcels available in Dacusville community with mountain views.

    01 Hood Road, Easley, SC 29640
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    Easley SC Acreage For Sale
    $1,900,000
    17.22 Acres

    Easley SC Acreage For Sale

    17+ acres near Easley, SC, ideal for development.

    00 Cardinal Drive, Easley, SC 29642
    View details
    Clemson Tailgating Lot For Sale
    $50,000
    0.01 Acres

    Clemson Tailgating Lot For Sale

    Tailgating lot near Clemson Football, behind the Esso Club.

    101 Oak Street, Clemson, SC 29630
    View details

    Pickens County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2395 commercial real estate for sale in Pickens County, SC, showcased through 107 active listings on our real estate platform. These investment opportunities span a total of 14,229,366 square feet of properties for sale, with an estimated market value of $51,505,259.

    Sale prices for business properties in Pickens County, SC start at $99,000, averaging $1,226,315, and reaching up to $6,296,296 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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