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    Pickens County, SC Commercial Real Estate for Sale

    272 results
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    Unique Office Building Near Courthouse
    $350,000
    0.16 Acres

    Unique Office Building Near Courthouse

    113 Court St, Pickens, SC 29671

    Commercial office building with two units and distinctive architectural features.

    • Prime commercial location next to the Pickens County Court House.
    • Two rental units provide additional income potential.
    • Unique architectural features: soaring wood ceilings, solid wood beams, brick accents, and a double brick fireplace.
    • Flexible floor plan with spacious meeting and conference rooms, kitchenette, and open work areas.
    • Private brick courtyard provides natural light and an appealing outdoor space.
    Updated: Nov 25, 2025
    View details
    Easley Multi-Family Property For Sale
    $500,000
    4.49 Acres

    Easley Multi-Family Property For Sale

    100 Hidden Acres Dr, Easley, SC 29640

    Multi-family property on 4.49 acres in Easley, South Carolina.

    • Multi‑family property on 4.49 acres.
    • Situated in Easley, South Carolina.
    • Electric heating.
    • Forced air heating.
    • Construction materials: See Remarks.
    Updated: Sep 2, 2025
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    Commercial Space in Downtown Clemson
    Pending
    $699,000

    Commercial Space in Downtown Clemson

    Rare opportunity to purchase commercial space in downtown Clemson.

    105 Sloan St, Clemson, SC 29631
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    Downtown Easley Retail Opportunity
    Contact for pricing

    Downtown Easley Retail Opportunity

    2,000 SF retail space in downtown Easley, SC.

    106 N Pendleton St, Easley, SC 29640
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    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Blvd, Clemson, SC 29631
    View details
    Clemson Development Opportunity
    $1,299,774
    7.66 Acres

    Clemson Development Opportunity

    7+ acres zoned for hotel or multifamily development near Clemson.

    76 Hwy W, Clemson, SC 29631
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    Spacious Mobile Home on Large Lot
    $139,000
    1,216 SF

    Spacious Mobile Home on Large Lot

    3 bed, 2 bath mobile home near Downtown Easley.

    123 Twin Pond Rd, Easley, SC 29640
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    Charming Mobile Home with Garage
    $139,000
    726 SF

    Charming Mobile Home with Garage

    Two-bedroom mobile home on spacious lot near downtown Easley.

    110 Twin Pond Rd, Easley, SC 29640
    View details
    Doublewide Mobile Home on Acreage
    $100,000

    Doublewide Mobile Home on Acreage

    Spacious 3BR/2BA mobile home on 0.73-acre fenced lot.

    326 Chesapeake Trl, Pickens, SC 29671
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    Gorgeous Townhome in Patrick Square
    $432,500
    1,620 SF

    Gorgeous Townhome in Patrick Square

    Practically new 2-bedroom, 2.5-bath townhome with modern features and amenities.

    174 Thomas Green Blvd, Clemson, SC 29631
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    Remodeled Home on One Acre
    $159,900
    1,144 SF

    Remodeled Home on One Acre

    Move-in ready 3 bed, 2 bath home near Pickens.

    308 Love And Care Rd, Six Mile, SC 29682
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    Easley Commercial Building - Great Location
    $164,900
    0.59 Acres

    Easley Commercial Building - Great Location

    High-traffic area, updated systems, includes business.

    1453 Gentry Memorial Hwy, Easley, SC 29640
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    Pickens Office Building - Great Potential
    $300,000
    0.76 Acres

    Pickens Office Building - Great Potential

    Spacious office building, ample parking, city limits.

    837 Pendleton Street Ext, Pickens, SC 29671
    View details
    Clemson Commercial Land - 7.66 Acres
    $1,299,774
    7.66 Acres

    Clemson Commercial Land - 7.66 Acres

    Prime Clemson location, ideal for hotel or multi-family development.

    00 Hwy 76 Hwy, Clemson, SC 29631
    View details
    Easley Industrial Warehouse - 6800 SF
    $1,250,000
    1.52 Acres

    Easley Industrial Warehouse - 6800 SF

    Prime Easley location, 6800 sq ft warehouse, 1.52 acres.

    416 Rolling Hills Cir, Easley, SC 29640
    View details
    Pickens Commercial Lot - Great Potential
    $59,500
    0.75 Acres

    Pickens Commercial Lot - Great Potential

    Level lot, high visibility, multi-use potential.

    000 Moorefield Memorial Hwy, Pickens, SC 29671
    View details
    Easley Commercial Land - Huge Potential
    $150,000
    0.92 Acres

    Easley Commercial Land - Huge Potential

    Prime Easley location, nearly an acre, high visibility.

    13-16 A St, Easley, SC 29640
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    Downtown Pickens Commercial Gem
    $895,000
    0.68 Acres

    Downtown Pickens Commercial Gem

    Prime location, versatile space, renovation underway.

    509 Lewis St, Pickens, SC 29671
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    Pickens Commercial Land Opportunity
    $50,000
    1.00 Acre

    Pickens Commercial Land Opportunity

    Acre lot, prime location, $50,000

    4000 Moorefield Memorial Hwy, Pickens, SC 29671
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    Historic Easley Commercial Gem
    $689,900
    0.70 Acres

    Historic Easley Commercial Gem

    Prime Downtown Location, 8,000 sq ft

    439 Main St, Easley, SC 29640
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    Easley Commercial Trio - High Potential
    $278,999
    0.40 Acres

    Easley Commercial Trio - High Potential

    Three established businesses in one building. High-traffic location.

    602 Liberty Dr, Easley, SC 29640
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    Dollar General Net Lease Investment
    $846,720
    9,100 SF

    Dollar General Net Lease Investment

    Easley, SC Retail Property - Strong Tenant

    3711 Farrs Bridge Rd, Easley, SC 29640
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    Downtown Liberty Restaurant Space
    $120,000
    1,800 SF

    Downtown Liberty Restaurant Space

    Prime Retail Location, $120,000

    25 Commerce St, Liberty, SC 29657
    View details
    Pickens Restaurant - Turnkey Opportunity
    $350,000
    1,456 SF

    Pickens Restaurant - Turnkey Opportunity

    Fully equipped restaurant, vacant, ready to operate.

    203 Farrs Bridge Rd, Pickens, SC 29671
    View details

    Pickens County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2197 commercial real estate investment opportunities in Pickens County, SC with 272 listings featured on our commercial real estate marketplace. The current inventory includes 833,515,286 square feet of properties with an estimated value of $635,737,598.

    Estimated prices for commercial real estate in Pickens County, SC begin at $32,500, with an average of $722,429 and extend to $17,830,000.

    In Pickens County, SC, current investment values show:

    • Retail properties positioned at $787,351
    • Other commercial real estate measuring $382,366
    • Land assessed at $444,111
    • Office Properties & Spaces calculated at $554,428
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    Browse Commercial real estate for Sale Near Pickens, SC

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