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    Orangeburg County, SC Commercial Real Estate for Sale

    194 results
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    Commercial Property in Orangeburg, SC
    $195,000
    2,016 SF

    Commercial Property in Orangeburg, SC

    610 Laurel St, Orangeburg, SC 29115

    Commercial property for sale with existing lease and tenants.

    • Income‑generating property with existing lease in place ($1800/month)
    • Relatively new roof and plumbing
    • Durable brick construction
    • Central heating and air conditioning
    • Existing tenants described as 'excellent'
    Updated: Mar 10, 2025
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    Historic Commercial Gem in North
    $50,000
    2,300 SF

    Historic Commercial Gem in North

    508 Main St, North, SC 29112

    Charming commercial property with endless possibilities in a central location.

    • Historic brick building with unique charm and character.
    • Flexible layout suitable for various business or community uses.
    • Visible, central location in the heart of North, SC, just off the main corridor.
    • City water and sewer connections.
    • Manageable .056‑acre lot.
    Updated: Aug 20, 2025
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    Restaurant Building in High-Traffic Area
    $150,000
    448 SF

    Restaurant Building in High-Traffic Area

    Vacant restaurant building with high visibility and commercial zoning.

    1168 John C. Calhoun Dr, Orangeburg, SC 29115
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    Income-Generating Mixed-Use Property
    $625,000
    9,044 SF

    Income-Generating Mixed-Use Property

    Nine income streams in revitalizing Elloree, South Carolina.

    2737 Cleveland St, Elloree, SC 29047
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    Restaurant Space in Elloree, SC
    $175,000
    1,600 SF

    Restaurant Space in Elloree, SC

    Restaurant space with kitchen, dining area, and ample parking.

    2727 Cleveland St, Elloree, SC 29047
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    Eutawville Commercial Property For Sale
    $160,000
    4,028 SF

    Eutawville Commercial Property For Sale

    4,028 sq ft commercial space on 0.84 acres.

    242 Porcher Ave, Eutawville, SC 29048
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    Highway Commercial Property with Storage
    $1,900,000
    3,282 SF

    Highway Commercial Property with Storage

    Commercial building with storage units near I-95 in Santee.

    9158 Old Number Six Hwy, Santee, SC 29142
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    Commercial Investment Opportunity in Elloree
    $275,000
    0.11 Acres

    Commercial Investment Opportunity in Elloree

    Investment property in historic Elloree, SC, with immediate and future income.

    2720 Cleveland St, Elloree, SC 29047
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    Historic Elloree Event Venue
    $175,000
    1,600 SF

    Historic Elloree Event Venue

    Income-producing event venue in historic Elloree, South Carolina.

    2725 Cleveland St, Elloree, SC 29047
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    Waterfront Home on Lake Marion
    $289,000
    840 SF

    Waterfront Home on Lake Marion

    Two-bedroom waterfront home with dock on Lake Marion, South Carolina.

    232 Ash Hill Dr, Eutawville, SC 29048
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    Newer Home on Peaceful Acreage
    $249,900
    1,456 SF

    Newer Home on Peaceful Acreage

    Built in 2022, 3 bed, 2 bath home on 4 acres.

    338 Westbury Rd, Bowman, SC 29018
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    Prime Commercial Property in Orangeburg
    $60,000

    Prime Commercial Property in Orangeburg

    High-visibility commercial property in downtown Orangeburg, suitable for various ventures.

    141 Boulevard St, Orangeburg, SC 29115
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    Prime Commercial Property in Orangeburg
    $60,000

    Prime Commercial Property in Orangeburg

    High-visibility retail storefront in downtown Orangeburg, suitable for various ventures.

    141 Boulevard St, Orangeburg, SC 29115
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    Turnkey Restaurant in Norway, SC
    $349,000
    2,800 SF

    Turnkey Restaurant in Norway, SC

    Fully equipped, 2800 sq ft restaurant.

    8291 Savannah Hwy, Norway, SC 29113
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    Downtown Elloree Commercial Gem
    $475,000
    6,060 SF

    Downtown Elloree Commercial Gem

    Retail, Apartments, High Traffic Location

    2701 Cleveland St, Elloree, SC 29047
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    Prime Orangeburg Commercial Building
    $269,000
    1,529 SF

    Prime Orangeburg Commercial Building

    Versatile space, high traffic area, great investment.

    750 Russell St, Orangeburg, SC 29115
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    this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer: CMLS has not reviewed and
    $200,000
    1,644 SF

    this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer: CMLS has not reviewed and

    therefore

    495 Dantzler St, Orangeburg, SC 29115
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    Lakefront Condo with Balcony
    $225,500
    1,251 SF

    Lakefront Condo with Balcony

    Two-bedroom, two-bathroom condo with lake views and balcony.

    161 Ballard Ln, Santee, SC 29142
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    Orangeburg Industrial Warehouse
    $11,700,000
    260,863 SF

    Orangeburg Industrial Warehouse

    260,863 SF Warehouse, Newly Renovated

    3771 Cameron Rd, Orangeburg, SC 29115
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    Prime Orangeburg Storefront
    $309,900
    5,884 SF

    Prime Orangeburg Storefront

    5,884 SF Retail Space, Vacant

    280 Meeting St, Orangeburg, SC 29115
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    Prime Orangeburg Office Building
    $399,900
    5,840 SF

    Prime Orangeburg Office Building

    5,840 SF Office Space, $399,900

    1408 Russell St, Orangeburg, SC 29115
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    Orangeburg Retail Pharmacy Investment
    $425,000
    15,404 SF

    Orangeburg Retail Pharmacy Investment

    15,404 SF Pharmacy, 100% Occupied

    946 State Rd, Orangeburg, SC 29115
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    Magnolia Village Parkway Retail Investment
    Contact for pricing

    Magnolia Village Parkway Retail Investment

    Retail property shadow-anchored to Walmart Supercenter and Lowe’s.

    133 Magnolia Vlg Pkwy, Orangeburg, SC 29118
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    Mixed-Use Retail Opportunity
    Contact for pricing
    29,000 SF

    Mixed-Use Retail Opportunity

    29,000 SF mixed-use or large retail opportunity for sale.

    1204 Brickle St, Orangeburg, SC 29118
    View details

    Orangeburg County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2710 commercial real estate investment opportunities in Orangeburg County, SC with 194 listings featured on our commercial real estate marketplace. The current inventory includes 298,878,967 square feet of properties with an estimated value of $382,354,226.

    Estimated prices for commercial real estate in Orangeburg County, SC begin at $32,500, with an average of $668,451 and extend to $20,000,000.

    In Orangeburg County, SC, current investment values show:

    • Retail properties positioned at $616,587
    • Individual retail properties measuring $525,079
    • Land assessed at $559,970
    • Retail space calculated at $351,844
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