Lancaster, PA Office Buildings for Sale

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East Stroudsburg, PA Millersville, PA East Petersburg, PA Willow Street, PA Lititz, PA Mountville, PA Leola, PA Ronks, PA

16 properties

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Updated: Aug 23

Multi-Suite Medical Office Building

2445 Marietta Ave, Lancaster, PA 17601

$1,500,000

5,000 sqft 2.80 AC lot

Two‑suite medical and professional office property totaling 5,000 SF
Suite 1 measures 3,500 SF and includes nine exam rooms
Suite 2 measures 1,500 SF with four private offices and storage
Property encompasses 2.8 acres, including a neighboring 1‑acre parcel
On‑site parking and visibility from Route 30

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Updated: Jul 28, 2025

Freestanding Two-Story Bank Building

2132 Marietta Avenue, Lancaster, PA 17603

$725,000

3,826 sqft

Freestanding two‑story bank and office building at 2132 Marietta Avenue
Three drive‑through lanes, including an ATM lane
First‑floor lobby with teller stations, private offices, and conference room
Second‑floor office space with lunchroom and restroom
VC - Village Center Zone designation

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Downtown Lancaster Assemblage For Sale

37-45 North Duke Street, Lancaster, PA 17603

$2,295,000

30,008 sqft

Three-parcel assemblage in downtown Lancaster with single tenant net lease.

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Three-Story Brick Building For Sale

100 North Queen Street, Lancaster, PA 17603

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77,294 sqft

Three-story brick building with finished lower level and outside space.

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Masonic Center Office Building

213 W Chestnut St, Lancaster, PA 17603

$3,050,000

41,088 sqft

Commercial Central Business zoning supports office, institutional, and mixed-use development options.

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Private Outdoor Viewing Deck Office Building

311 HARRISBURG AVENUE, Lancaster, PA 17603

$4,250,000

Office building converted from a tobacco warehouse with a private outdoor viewing deck into Penn Medicine Stadium.

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Single-Story Mixed-Use Property

1410 Oregon Pike, Lancaster, PA 17602

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4,500 sqft 0.20 AC lot

Masonry mixed-use building with on-site parking, public water and sewer, and B-4 zoning.

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Historic Office Building with Carriage House

802 N Duke St, Lancaster, PA 17602

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11,680 sqft 0.50 AC lot

Renovated commercial setting with ornate architectural details, flexible interior areas, and a separate residential-style carriage house.

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Historic Office Building with Parking

48 50 W Chestnut Street, Rohrerstown, PA 17603

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77,135 sqft 1.48 AC lot

Multi-tenant office property with available space, on-site parking, and a downtown Lancaster setting.

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Historic Office Building

48-50 W Chestnut St, Lancaster, PA 17608

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77,135 sqft 1.48 AC lot

Historic Indiana Limestone office property with leased space, additional capacity, and four condominium units.

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Commercial Office/Retail Building

2205 Oregon Pike, Lancaster, PA 17601

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4,435 sqft

Well-maintained office building currently totaling 4,435 SF and zoned for Commercial Office/retail use.

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Vacant Multi-Story Office Building

101 W James St, Lancaster, PA 17603

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Former financial-services property with a detached drive-through canopy, secure vault, and on-site parking.

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Renovated Cottage Office Building

3000 Columbia Ave, Lancaster, PA 17603

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Owner-renovated interior supports office use within a commercially zoned property.

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Corporate Headquarters Office Building

1770 Hempstead Road, Lancaster, PA 17601

$443,993

14,095 sqft

Recently constructed office space in a corporate headquarters building available for sale.

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Stabilized Office Investment Opportunity

3020 Columbia Ave, Lancaster, PA 17603

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39,610 sqft 2.68 AC lot

39,610 SF office building on 2.68 acres for sale.

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Professional Office Building

160 N Pointe Boulevard Unit 108, Lancaster, PA 17601

$35,255

Remodeled common areas, central air, parking, and access to Rt. 30 support professional and medical office use.

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Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 16 Active listings in Lancaster, PA, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 3 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Freestanding Office Condominium

342 E Main St, Leola, PA 17540

$1,095,000

6,490 sqft

Two-level office property with private suites, shared meeting areas, and occupied second-floor offices along East Main Street.

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Office Building with Retail Opportunity

743 S BROAD Street, Lititz, PA 17543

$2,400,000

9,200 sqft 0.96 AC lot

A 9,200 sf office building on nearly an acre with direct highway visibility and adjacent banking frontage.

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Medical Office Building with Imaging Power

640 E OREGON Road, Lititz, PA 17543

$2,100,000

1.50 AC lot

Medical suites with separate entrances and heavy power for imaging equipment in a parking-rich setting.

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Professional Office Building

352 E Main Street, Leola, PA 17540

$1,175,000

High-visibility office building offering two executive suites plus leased individual offices.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Highway Commercial Land

50 W 28TH DIVISION Highway, Lititz, PA 17543

$599,000

2.71 AC lot

Highway Commercial-zoned land sits beside Tractor Supply, Hearthside Furniture, Copper Cup, and Turkey Hill.

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Corner Commercial Land

2540 CAPE HORN Road, Red Lion, PA 17356

$850,000

1.96 AC lot

Level, commercially zoned parcel positioned near established retail, banking, residential, and community destinations.

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Commercial Land with Utilities

LEWISBERRY Road, Etters, PA 17319

$75,000

3.67 AC lot

Regional Commercial Office zoning with sewer and water available and exposure to I-83.

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Lancaster, PA Office Buildings Market Trends and Statistics

Explore 16 office buildings for sale in Lancaster, PA, showcased through 16 active listings on our real estate platform. These investment opportunities span a total of 385,806 square feet of properties for sale, with an estimated market value of $12,299,248.

Sale prices for office properties in Lancaster, PA start at $35,255, averaging $1,757,035, and reaching up to $4,250,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 175K

Population Growth (5Y) +4.0%

Median Household Income $81,785

College Educated 18.8%

High-Yield Neighborhoods for Investment

Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
17601	$659.7K
17603	$2.6M

Taxes & Financing

Tax Rate (average for all types) 2.75%

Property Tax per SF $25.11 per SF

Tax Rate vs County Average 0.37 pp above county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Lancaster County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Lancaster fall within the 100,000+ square foot range.

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