Newfane, NY Commercial Real Estate for Sale

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Lockport, NY Olcott, NY Appleton, NY
Former Hospital Building in Newfane
Updated: Nov 21, 2025
Former Hospital Building in Newfane

2600 William Street, Newfane, NY 14108

$1,400,000
70,547 sqft
Large 63,106 sq ft main building with 74 rooms suitable for medical, nursing home, senior housing conversion, or adaptive reuse.
7.5‑acre site with ample parking (approximately 200 spaces) at the front and rear.
Existing Heliport on‑site, used by Mercyflight and Niagara County Sheriff's Office.
Includes a secondary 7,441 sq ft structure.
Recreation area with a basketball court in the central courtyard.
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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 1 Active listings in Newfane, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 71 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Warehouse Garage with Unfinished Loft
Warehouse Garage with Unfinished Loft

4652 Thilk Drive, Wilson, NY 14172

$275,000
4,398 sqft · 1.50 AC lot

Freestanding warehouse with three oversized bays and an unfinished upper level, ready for buildout with septic.

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Land
Land

4652 Thilk Dr, Wilson, NY 14172

$275,000

Flex space

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Lockport Medical & Professional Office
Lockport Medical & Professional Office

Pendleton, NY 14094

Contact for pricing

Medical and professional office park with multiple buildings for sale.

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Commercial Land Corner Location
Commercial Land Corner Location

Transit Road and Tonawanda Creek Road, Pendleton, NY 14094

Contact for pricing

Corner commercial land with redevelopment potential in Pendleton, NY.

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Off-Market Properties in Newfane, NY

Consider similar Off-Market properties in Newfane, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

Charlotteville Rd
MEDICAL CLINIC

Charlotteville Rd, Newfane, NY 14108

Value Estimation by Request
51,192 sqft · 6.20 AC lot
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2555 Main St
GROCERY, SUPERMARKET

2555 Main St, Newfane, NY 14108-1043

Value Estimation by Request
18,371 sqft · 1.80 AC lot
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2244 Lockport Olcott Rd
OFFICE/RESIDENTIAL (MIXED USE)

2244 Lockport Olcott Rd, Newfane, NY 14108-9514

Value Estimation by Request
2,580 sqft · 3.90 AC lot
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2751 Main St
OFFICE/RESIDENTIAL (MIXED USE)

2751 Main St, Newfane, NY 14108-1246

Value Estimation by Request
3,978 sqft · 0.21 AC lot
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3586 Beebe Rd
SERVICE STATION WITH FOOD MART

3586 Beebe Rd, Newfane, NY 14108-9659

Value Estimation by Request
2,382 sqft · 2.00 AC lot
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2598 Main St
BAR, TAVERN

2598 Main St, Newfane, NY 14108-1021

Value Estimation by Request
5,248 sqft · 2.80 AC lot
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2501 Lockport Olcott Rd
GOLF COURSE

2501 Lockport Olcott Rd, Newfane, NY 14108-9519

Value Estimation by Request
2,246 sqft · 21.80 AC lot
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6036 Ketchum Ave
DISTRIBUTION WAREHOUSE

6036 Ketchum Ave, Newfane, NY 14108-1013

Value Estimation by Request
26,318 sqft · 2.00 AC lot
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2728 Main St
OFFICE/RESIDENTIAL (MIXED USE)

2728 Main St, Newfane, NY 14108-1249

Value Estimation by Request
3,140 sqft · 0.16 AC lot
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3333 Lockport Olcott Rd
RESTAURANT

3333 Lockport Olcott Rd, Newfane, NY 14108-9725

Value Estimation by Request
11,402 sqft · 10.20 AC lot
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2567 Main St
STORE/OFFICE (MIXED USE)

2567 Main St, Newfane, NY 14108-1018

Value Estimation by Request
3,040 sqft · 0.36 AC lot
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2789 Main St
WAREHOUSE, STORAGE

2789 Main St, Newfane, NY 14108-1234

Value Estimation by Request
2,256 sqft · 0.25 AC lot
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2779 Main St
OFFICE/RESIDENTIAL (MIXED USE)

2779 Main St, Newfane, NY 14108-1236

Value Estimation by Request
10,000 sqft · 0.68 AC lot
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6127 1st St
DISTRIBUTION WAREHOUSE

6127 1st St, Newfane, NY 14108-1201

Value Estimation by Request
1,728 sqft · 0.20 AC lot
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6139 Ee Ave
OFFICE/RESIDENTIAL (MIXED USE)

6139 Ee Ave, Newfane, NY 14108-1334

Value Estimation by Request
5,152 sqft · 1.00 AC lot
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2337 Lockport Olcott Rd
VEHICLE SALES, RENTALS

2337 Lockport Olcott Rd, Newfane, NY 14108-9510

Value Estimation by Request
7,724 sqft · 6.96 AC lot
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2905 Beebe Rd
MANUFACTURING (LIGHT)

2905 Beebe Rd, Newfane, NY 14108-9655

Value Estimation by Request
6,850 sqft · 3.22 AC lot
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2990 Lockport Olcott Rd
RESTAURANT

2990 Lockport Olcott Rd, Newfane, NY 14108-9602

Value Estimation by Request
6,000 sqft · 1.40 AC lot
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2600 William St
MEDICAL CLINIC

2600 William St, Newfane, NY 14108-1026

$690,000
Estimated value
53,806 sqft · 7.20 AC lot
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Wallace Ave
VACANT COMMERCIAL LAND

Wallace Ave, Newfane, NY 14108

$680,000
Estimated value
0.36 AC lot
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Main St
VACANT COMMERCIAL LAND

Main St, Newfane, NY 14108

$675,000
Estimated value
0.21 AC lot
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6037 Ketchum Ave
VACANT COMMERCIAL LAND

6037 Ketchum Ave, Newfane, NY 14108-1014

$650,000
Estimated value
11,680 sqft · 4.00 AC lot
View details
2776 Main St
OFFICE/RESIDENTIAL (MIXED USE)

2776 Main St, Newfane, NY 14108-1206

Value Estimation by Request
960 sqft · 0.07 AC lot
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Newfane, NY Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Newfane, NY on our real estate platform. These investment opportunities span a total of 70,547 square feet of properties for sale, with an estimated market value of $1,400,000.

Sale prices for business properties in Newfane, NY start at $1,400,000, averaging $1,400,000, and reaching up to $1,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 5,301
Population Growth (5Y) -12.8%
Median Household Income $72,977
College Educated 40.6%

High-Yield Neighborhoods for Investment

Identify Newfane submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
14108 $1.4M

Listings Trend

New vs delisted commercial listings in Niagara County

New Delisted

Total CRE Inventory on Market (SF)

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