Portsmouth, NH Commercial Real Estate for Sale

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Compact Medical Office Condo
Updated: Jun 2
Compact Medical Office Condo

230 Lafayette Rd Unit 11D, Portsmouth, NH 03801

$94,160
428 sqft
Medical office condominium (Unit 11D) at 230 Lafayette Road, approx. 428± SF
Private, in‑suite restroom
Located in Lafayette Professional Park
Ample on‑site parking
~1 mile to downtown Portsmouth
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230 Lafayette Rd Unit 11D, Portsmouth, NH 03801

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Renovated Mixed-Use Building
Updated: Apr 22
Renovated Mixed-Use Building

8 Bow Street, Portsmouth, NH 03801

$4,200,000
4,101 sqft 0.03 AC lot
Four residential units plus one commercial suite
4,101 square feet on a 0.03‑acre lot
Renovated during 2017–2018; original construction dates to 1810
Ground‑floor commercial space currently used by Bangor Savings Bank
Four private storage areas plus two washers and two dryers in the basement
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Historic Office Building
Historic Office Building

144 Washington Street, Portsmouth, NH 03801

$3,300,000
0.25 AC lot

Federal-style professional office property with period details, public water, and off-street parking in Portsmouth’s South End.

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Medical Office Condominium
Medical Office Condominium

330 Borthwick Avenue, Portsmouth, NH 03801

$550,000

Condominium office setting across from Portsmouth Regional Hospital with on-site parking and direct regional highway access.

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Ground-Floor Retail Condominium
Ground-Floor Retail Condominium

53 Green St, Portsmouth, NH 03801

$1,195,000
2,828 sqft

Cold, dark shell offers flexibility for a custom commercial build-out.

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Street-Level Retail Condominium
Street-Level Retail Condominium

40 Bridge Street Unit 101, Portsmouth, NH 03801

$2,350,000

Flexible commercial unit with storefront glazing, multiple entrances, and upgraded interior systems.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

98 Cornwall Street, Portsmouth, NH 03801

$1,000,000
0.41 AC lot

Waterfront property with existing industrial and office buildings, direct water access, and flexible commercial or residential possibilities.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

94 Langdon Street, Portsmouth, NH 03801

$1,000,000
0.16 AC lot

Waterfront setting with existing industrial and office improvements, public utilities, and MRB zoning.

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Retail Condominium Unit
Retail Condominium Unit

135 Market Street, Unit G, Portsmouth, NH 03801

$715,000
994 sqft

Leased retail condo in a well-maintained building with prominent signage along Market Street.

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Restaurant with Dining Rooms and Bars
Restaurant with Dining Rooms and Bars

175 High Street, Portsmouth, NH 03801

$149,000

Includes a working kitchen, walk-in coolers, storage, and seasonal outdoor patio space.

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Renovated Office Condominium Unit
Renovated Office Condominium Unit

118 Maplewood Avenue, Portsmouth, NH 03801

$250,000

Two-room office condominium with a full bathroom, assigned parking, and immediate occupancy availability.

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Recently Built Office Units
Recently Built Office Units

1-54 Maplewood Ave, Portsmouth, NH 03801

$3,440,000
4,862 sqft

Downtown commercial space includes on-site parking and access to nearby public parking options.

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Auto Shop with Overhead Doors
Auto Shop with Overhead Doors

930 Route 1 Bypass, Portsmouth, NH 03801

$825,000

B-zoned commercial building with basement and public water service.

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Downtown Office Condominium Suite
Downtown Office Condominium Suite

118 Maplewood Avenue, #C1, Portsmouth, NH 03801

$450,000
951 sqft

Versatile office condo with three private offices, conference room, restroom, kitchenette, and two dedicated parking spaces.

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Downtown Office Condominium Suite
Downtown Office Condominium Suite

118 Maplewood Avenue, Unit C-1, Portsmouth, NH 03801

$450,000
951 sqft

Own a functional office condominium with private offices, a conference room, and dedicated on-site parking.

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Historic Downtown Office Building
Historic Downtown Office Building

40 Congress Street, Portsmouth, NH 03801

$12,500,000
22,601 sqft 0.09 AC lot

CD5 zoning supports office, commercial, and mixed-use applications.

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Two-Building Flex Industrial Site
Two-Building Flex Industrial Site

3601 Lafayette Road, Portsmouth, NH 03801

$1,300,000
2,615 sqft 4.50 AC lot

Two commercial buildings on 4.5 acres include offices and a rear workshop/warehouse with four drive-in doors.

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Office Condominium with Private Offices
Office Condominium with Private Offices

C1-118 Maplewood Ave, Portsmouth, NH 03801

$450,000
951 sqft

Professional suite includes three enclosed offices, a flexible conference room, kitchenette, storage, and a private restroom.

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Waterfront Restaurant Site with Full Bar
Waterfront Restaurant Site with Full Bar

990 Lafayette Rd, Portsmouth, NH 03801

Contact for pricing
17,900 sqft 2.80 AC lot

Owner-occupied restaurant with a full bar and seating for 214, positioned on a high-visibility US Rt 1 waterfront site.

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Mixed-Use Investment Opportunity
Mixed-Use Investment Opportunity

165-172 Hanover Street, Portsmouth, NH 03801

Contact for pricing
12,780 sqft

Mixed-use property with income and growth potential in downtown location.

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Renovated Furnished Office Unit
Renovated Furnished Office Unit

6 Greenleaf Woods Drive, Portsmouth, NH 03801

$249,000
1,418 sqft

Three private offices use glass walls and doors to balance separation with natural light.

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Medical Office Condominium Suite
Medical Office Condominium Suite

200 Griffin Rd, Portsmouth, NH 03801

Contact for pricing
2,870 sqft

Office suite includes a waiting room, reception area, nine exam rooms, private offices, and ample on-site parking.

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Medical Office Condominium Across Hospital
Medical Office Condominium Across Hospital

330 Borthwick Ave 210, Portsmouth, NH 03801

$550,000

Medical or professional users benefit from on-site parking and immediate access to major area routes.

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Retail Space with Loading Bays
Retail Space with Loading Bays

720 Lafayette Rd, Portsmouth, NH 03801

$8,500,000

Occupied commercial space offers covered drive-up access and infrastructure for loading, unloading, and customer pickup.

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Portsmouth, NH Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Portsmouth, NH, showcased through 42 active listings on our real estate platform. These investment opportunities span a total of 105,946 square feet of properties for sale, with an estimated market value of $69,307,160.

Sale prices for business properties in Portsmouth, NH start at $94,160, averaging $2,235,714, and reaching up to $13,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 23K
Population Growth (5Y) +2.9%
Median Household Income $106,520
College Educated 17.1%

High-Yield Neighborhoods for Investment

Identify Portsmouth submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
03801 $1.4M

Taxes & Financing

Tax Rate (average for all types) 1.49%
Property Tax per SF $10.47 per SF
Tax Rate vs County Average 0.23 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Rockingham County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Portsmouth fall within the 100,000+ square foot range.

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