Portsmouth, NH Medical Office Space for Lease

List

Map

Rye, NH Hampton, NH Greenland, NH North Hampton, NH Kittery, ME Stratham, NH Newington, NH Exeter, NH

13 properties

Sort:

Updated: May 26, 2022

Office Unit with Tidal Flats Views

4 greenleaf woods Drive, Portsmouth, NH 03801

Contact for pricing

Unit 6 measures 144 sf and overlooks tidal flats and a natural area
Windows on 3 sides provide natural light and exterior views
Shared professional office setting with health care practitioners and therapists
Reception, IT/storage rooms, kitchenette, and private bath with shower
On‑site parking with access just off Route 1 at the bypass

View details

Updated: Aug 26

Professional Office Unit with Natural Light

4 Greenleaf Woods Dr Unit 301, Portsmouth, NH 03801

$595/Mo

6,414 sqft

144‑square‑foot Unit 6 with views toward tidal flats and a natural area
7‑office layout with reception, IT/storage rooms, kitchenette, and private bath with shower
Recently upgraded unit and building with windows on three sides
Utilities and internet included
Ample on‑site parking in a campus‑style complex

View details

Portsmouth Commercial Space For Rent

875 Greenland Rd 8, Portsmouth, NH 03801

$15 SF/Yr

2,333 sqft 6.64 AC lot

2,333± SF commercial space in a convenient Portsmouth location.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Medical Office Space Opposite Walmart

2299 Woodbury Ave, Portsmouth, NH 03801

$2,000/Mo

Professional and medical users share a building with client parking and included utilities.

View details

Renovated Medical Office Space

875 Greenland Road #8, Portsmouth, NH 03801

$15 SF/Yr

Recently renovated office space with natural light, on-site parking, and convenient I-95 access.

View details

Renovated Professional Office Suites

4 Greenleaf Woods Dr, Portsmouth, NH 03801

Contact for pricing

100 sqft

Renovated office suites offer flexible space with private bathrooms, kitchenette, and reception and conference areas.

View details

First-Floor Medical Office Suite

230 Commerce Way, Portsmouth, NH 03801

Contact for pricing

50,020 sqft

First-floor suite with direct access from the front lobby, suited for medical or professional use.

View details

Medical Office Suite

875 Greenland Road, Building C, Unit 8, Portsmouth, NH 03801

$15 SF/Yr

Commercial space near I-95 and Route 1 with access to Portsmouth and the Seacoast.

View details

Renovated Medical Office Space

8-875 Greenland Rd, Portsmouth, NH 03801

$15 SF/Yr

Professional space with natural light, on-site parking, and convenient access to I-95.

View details

Medical and Office Suite

875 Greenland Road, Portsmouth, NH 03801

$15 SF/Yr

16,000 sqft

Recently renovated, light-filled office space suited for professional or medical use with ample on-site parking near I-95.

View details

Medical Office Suites For Lease

330 Borthwick Ave, Portsmouth, NH 03801

Contact for pricing

Prime medical office suites available near Portsmouth Regional Hospital.

View details

Office Units with On-Site Parking

4 Greenleaf Woods Drive, Portsmouth, NH 03801

$595/Mo

6,414 sqft

Updated professional offices support healthcare and therapy practices in a campus-style setting near downtown.

View details

Medical Office Suite with Private Bath

301-4 Greenleaf Woods Dr, Portsmouth, NH 03801

$595/Mo

Office suite includes a private bath with shower, kitchenette, and natural light from windows on three sides.

View details

Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 13 Active listings in Portsmouth, NH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Second-Floor Office Suite

201-155 Portsmouth Ave, Stratham, NH 03885

$4,500/Mo

3,000 sqft

Flexible professional space includes private rooms, reception, conference space, and a kitchenette.

View details

Office Unit With Treatment Rooms

1 Bayside Rd 101, Greenland, NH 03840

$2,150/Mo

1,519 sqft

Renovated commercial suite with multiple enclosed rooms, private bath facilities, and access to a shared parking area.

View details

Renovated Medical Office Suite

101-1 Bayside Rd, Greenland, NH 03840

$2,150/Mo

1,519 sqft

Renovated in 2025 with treatment rooms, private bathrooms, and laundry hookups.

View details

Second-Floor Office Suite

155 Portsmouth Avenue, Stratham, NH 03885

Contact for pricing

Flexible professional space with private rooms, shared work areas, parking, and convenient access in a Town Center setting.

View details

Similar Spaces for Sale in Portsmouth, NH

Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

Compact Medical Office Condo

230 Lafayette Rd Unit 11D, Portsmouth, NH 03801

$94,160

428 sqft

A private, in-suite restroom medical office suite with ample on-site parking and easy access to major routes.

View details

Medical Office Condominium Suite

200 Griffin Rd, Portsmouth, NH 03801

Contact for pricing

2,870 sqft

Office suite includes a waiting room, reception area, nine exam rooms, private offices, and ample on-site parking.

View details

Medical Office Condominium

330 Borthwick Avenue, Portsmouth, NH 03801

$550,000

Condominium office setting across from Portsmouth Regional Hospital with on-site parking and direct regional highway access.

View details

Medical Office Condominium

330 Borthwick Ave Unit 210, Portsmouth, NH 03801

$550,000

Professional suite in a medical building with on-site parking and accessible spaces.

View details

Medical Office Condominium

210-330 Borthwick Ave, Portsmouth, NH 03801

$550,000

Condominium office space across from Portsmouth Regional Hospital with accessible on-site parking and convenient regional highway connections.

View details

Portsmouth, NH Medical Office Space Lease Rates & Market Statistics

Explore 13 Medical Office Space listings for lease in Portsmouth, NH on Realmo, a commercial real estate exchange covering the Portsmouth area. The current inventory totals 81,281 square feet of properties — an average of ~6,250 SF per listing.

Asking lease rates for Medical Office Space in Portsmouth start at $1.11 SF/Yr, average $12.69 SF/Yr, and reach $15 SF/Yr at the top of the market. That's a 14x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $12.69 SF/Yr, the local average runs 20% below New Hampshire's state average of $15.81 SF/Yr.

Portsmouth accounts for 34% of the 38 medical office space listings currently available across Rockingham County, where nearby markets include Salem and Stratham. Medical Office Space listings make up 16% of the 81 Office Spaces currently for lease in Portsmouth, with asking rates averaging $12.69 SF/Yr — 29% below the citywide Office Spaces average of $17.79 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (72 listings) and Creative space (10 listings) elsewhere in the Portsmouth market.

List

Map