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    Portsmouth, NH Medical Office Space for Lease

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    Manchester, NH Nashua, NH Concord, NH
    Versatile Commercial Space on Lafayette Road
    Contact for pricing

    Versatile Commercial Space on Lafayette Road

    750 Lafayette Road, Portsmouth, NH 03801

    Adaptable space suitable for medical, retail, restaurant, or office use.

    • High‑traffic location on Lafayette Rd (Route 1) at a lighted intersection.
    • Adaptable space suitable for medical, retail, restaurant, or office use.
    • Existing infrastructure for medical/dental use, including exam rooms with water.
    • Private and public bathrooms already in place.
    • Potential to connect with adjacent unit for up to 5,650+/- SqFt with two retail frontages.
    Updated: Feb 24, 2025
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    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF

    Office or Medical Office Space

    14 Manchester Square, Portsmouth, NH

    Office or medical space in Portsmouth's Pease Tradeport.

    • Zoned for Retail Use: Unique opportunity as the only building at Pease Tradeport with this zoning.
    • Prime Location: Situated in Manchester Square at Pease Tradeport.
    • Suitable for Medical or Office Use: Ideal for outpatient medical groups or traditional office users.
    • Benefits from customer services like the Food Court and EZ Pass.
    • Located amongst other retail businesses.
    Updated: Nov 14, 2025
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    Medical Office Space Near Hospital
    $18 SF/Yr
    1,995 SF

    Medical Office Space Near Hospital

    Medical office suite for lease across from Portsmouth Regional Hospital.

    330 Borthwick Ave, Portsmouth, NH 3801
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    Medical Office Suites For Lease
    Contact for pricing

    Medical Office Suites For Lease

    Prime medical office suites available near Portsmouth Regional Hospital.

    330 Borthwick Ave, Portsmouth, NH 3801
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    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in Portsmouth, NH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Highly Visible Office/Medical Space
    $20 SF/Yr
    79,404 SF

    Highly Visible Office/Medical Space

    Adaptable office and medical space with high visibility and accessibility.

    118 Portsmouth Ave, Stratham, NH 3885
    View details
    Medical Building Suites Available
    $18 SF/Yr
    2,590 SF

    Medical Building Suites Available

    Medical suites for rent in premier outpatient building near Exeter Hospital.

    1 Hampton Rd, Exeter, NH 3833
    View details
    Class A Office Space Available
    Contact for pricing
    100,000 SF

    Class A Office Space Available

    High-end professional office space suitable for cafe or coffee shop.

    118 Portsmouth Ave, Stratham, NH 3885
    View details
    Medical Office Space for Lease
    Contact for pricing

    Medical Office Space for Lease

    Medical office suites available near Exeter Hospital on Route 27.

    1 Hampton Rd, Exeter, NH 3833
    View details

    Explore Similar Spaces for Sale in Portsmouth, NH

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Medical/Office Condo For Sale
    $300,000
    1,275 SF

    Medical/Office Condo For Sale

    1,275 SF medical/office condo in professionally managed office park.

    278 Lafayette Rd, Portsmouth, NH 3801
    View details
    Compact Medical Office Condominium
    $94,160
    428 SF

    Compact Medical Office Condominium

    Medical office condo ideal for new or expanding practices.

    230 Lafayette Road, Portsmouth, Portsmouth, NH 3801
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details
    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Winter Park Mixed-Use Opportunity
    $8,500 /Mo
    23,056 SF

    Winter Park Mixed-Use Opportunity

    Double commercial lot in Winter Park, FL, for lease.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Portsmouth, NH Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Portsmouth, NH with 4 listings featured on our commercial real estate exchange. The current inventory includes 7,743,835,440 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Medical Office Space in Portsmouth, NH begin at $15 SF/Yr, with an average of $15 SF/Yr and extend to $15 SF/Yr.
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