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    Portsmouth, NH Office Spaces for Sale

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    Rye, NH Greenland, NH North Hampton, NH
    15 results
    Historic Portsmouth Office Building For Sale
    $3,300,000
    0.25 Acres
    Historic Portsmouth Office Building For Sale

    144 Washington Street, Portsmouth, NH 03801

    Landmark Portsmouth building, ideal for professional offices or business.
    • Landmark Federal‑style residence in Portsmouth's historic Puddle Dock area with sweeping views.
    • One of the largest privately owned parcels in Portsmouth's South End with off‑street parking and potential for garage/carriage house.
    • Prime location: five‑minute walk to Market Square, Portsmouth's cultural epicenter.
    • Historic architectural details: genuine moldings, original eight‑panel doors, and distinctive dental moldings.
    • Versatile property suitable for residential or professional use, currently configured as professional offices.
    Updated: Dec 15, 2025
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    Downtown Portsmouth Commercial Condominium
    $2,350,000
    Downtown Portsmouth Commercial Condominium

    40 Bridge Street Unit 101, Portsmouth, NH 03801

    Adaptable commercial space in vibrant downtown Portsmouth.
    • Prime downtown Portsmouth location with high visibility and foot traffic.
    • 3,798± sq ft first‑floor commercial condominium with flexible layout.
    • Suitable for diverse commercial uses: retail, restaurant, medical, office, etc.
    • Convenient access with side and rear entrances.
    • Directly across from municipal parking lots, ensuring easy customer access.
    Updated: May 6
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    Islington Street Commercial Condo Space
    $429,900
    Islington Street Commercial Condo Space

    Turnkey commercial condo in Portsmouth's vibrant West End.

    369 Islington St A, Portsmouth, NH 3801

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    Portsmouth Industrial Condo For Sale
    $975,000
    5,100 SF
    Portsmouth Industrial Condo For Sale

    Modern 5,100 SF industrial condo in Portsmouth, NH for sale.

    280 Heritage Ave, Portsmouth, NH 3801

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    Medical/Office Condo For Sale
    $300,000
    1,275 SF
    Medical/Office Condo For Sale

    1,275 SF medical/office condo in professionally managed office park.

    278 Lafayette Rd, Portsmouth, NH 3801

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    Historic Portsmouth Office Building For Sale
    $3,300,000
    Historic Portsmouth Office Building For Sale

    Landmark Federal-style building in Portsmouth's historic Puddle Dock area.

    144 Washington St, Portsmouth, NH 3801

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    Downtown Portsmouth Office Suites Available
    $1,200,000
    2,117 SF
    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.

    10-0 Vaughan Mall, Portsmouth, NH

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    Downtown Portsmouth Commercial Investment Opportunity
    $3,440,000
    4,862 SF
    Downtown Portsmouth Commercial Investment Opportunity

    Commercial property in Portsmouth's vibrant downtown area with excellent accessibility.

    54-64 Maplewood Ave, Portsmouth, NH 3801

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    Downtown Office Condominium Suite
    $450,000
    951 SF
    Downtown Office Condominium Suite

    Own a functional office condominium with private offices, a conference room, and dedicated on-site parking.

    118 Maplewood Avenue, Unit C-1, Portsmouth, NH 3801

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    Portsmouth Commercial Office Condominium
    $250,000
    Portsmouth Commercial Office Condominium

    Commercial office condominium in Portsmouth, renovated in 2024.

    118 Maplewood Avenue, Portsmouth, NH 03801

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    Compact Medical Office Condominium
    $94,160
    428 SF
    Compact Medical Office Condominium

    Medical office condo ideal for new or expanding practices.

    230 Lafayette Road, Portsmouth, Portsmouth, NH 3801

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    Waterfront Office Condo For Sale
    $550,000
    1,291 SF
    Waterfront Office Condo For Sale

    Office condo with water views, close to downtown Portsmouth.

    500 Market St, Portsmouth, NH

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    Compact Medical Office Condo
    $94,160
    428 SF
    Compact Medical Office Condo

    A private, in-suite restroom medical office suite with ample on-site parking and easy access to major routes.

    230 Lafayette Rd Unit 11D, Portsmouth, NH 3801

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    Portsmouth Office Condo For Sale
    $450,000
    1,071 SF
    Portsmouth Office Condo For Sale

    1,071 SF office condo near I-95 and Market Square.

    500 Market Street, Portsmouth, NH 3801

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    Portsmouth Office Condo For Sale
    $250,000
    Portsmouth Office Condo For Sale

    Commercial office condo in Portsmouth, renovated in 2024.

    118 Maplewood Avenue 5, Portsmouth, NH 3801

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 15 Active listings in Portsmouth, NH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 57 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    York, ME Office Suite
    $249,900
    1,014 SF
    York, ME Office Suite

    Bright, renovated office suite in established medical building.

    1 Brickyard Lane, York, ME 03909

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    York, Maine Office Condo
    $65,000
    528 SF
    York, Maine Office Condo

    Professional office condo in York, Maine, ideal for small businesses.

    433 US Route 1, York, ME 03909

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    New Rye Commercial Building Opportunity
    $749,000
    916 SF
    New Rye Commercial Building Opportunity

    Freestanding 916 sq ft commercial building in Rye, NH.

    22 Pioneer Rd, Rye, NH 3870

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    Rye Airfield Investment Opportunity
    $10,000,000
    60,000 SF
    Rye Airfield Investment Opportunity

    Commercially zoned parcels with development potential in scenic Seacoast region.

    6 Airfield Drive, Rye, NH 3870

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in York Village
    $475,000
    0.33 Acres
    Prime Land in York Village

    Centrally located parcel with development potential near shops and restaurants.

    190 York Street, York, ME 03909

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    Dover Waterfront Land with Riparian Rights
    $3,750,000
    1.30 Acres
    Dover Waterfront Land with Riparian Rights

    Premier waterfront land with deepwater access in Dover's City Center.

    3 Cocheco Street, Dover, NH 03820

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    Barrington Commercial/Industrial Lot For Sale
    $650,000
    8.00 Acres
    Barrington Commercial/Industrial Lot For Sale

    8+ acre commercial/industrial lot with high visibility on Route 4.

    00 Old Concord Turnpike/US RT 4, Barrington, NH 03823

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    Downtown Exeter Development Opportunity
    $2,990,000
    1.53 Acres
    Downtown Exeter Development Opportunity

    1.5+ acre commercial land in Exeter's vibrant downtown.

    48 Lincoln Street, Exeter, NH 03833

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    Off-Market Properties in Portsmouth, NH

    Consider similar Off-Market properties in Portsmouth, NH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    500 Market St, Unit 1G
    CONDOMINIUM OFFICES
    1,071 SF
    Value Estimation by Request
    Unit 1G

    500 Market St, Portsmouth, NH 03801-3456

    View details
    8 Greenleaf Woods Dr
    CONDOMINIUM OFFICES
    33,988 SF
    Estimated value
    $4,940,000

    8 Greenleaf Woods Dr, Portsmouth, NH 03801-5454

    View details
    600 State St Ste, Unit 4
    CONDOMINIUM OFFICES
    1,209 SF
    Value Estimation by Request
    Unit 4

    600 State St Ste, Portsmouth, NH 03801-4370

    View details
    100 Griffin Rd, Unit A
    CONDOMINIUM OFFICES
    3,348 SF
    Estimated value
    $930,000
    Unit A

    100 Griffin Rd, Portsmouth, NH 03801-7158

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    150 Griffin Rd Ste, Unit 3
    CONDOMINIUM OFFICES
    5,465 SF
    Estimated value
    $1,340,000
    Unit 3

    150 Griffin Rd Ste, Portsmouth, NH 03801-7131

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    150 Griffin Rd Ste, Unit 1
    CONDOMINIUM OFFICES
    4,754 SF
    Estimated value
    $1,190,000
    Unit 1

    150 Griffin Rd Ste, Portsmouth, NH 03801-7131

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    1 Cate St, Unit 3A
    CONDOMINIUM OFFICES
    2,560 SF
    Estimated value
    $610,000
    Unit 3A

    1 Cate St, Portsmouth, NH 03801-7108

    View details
    100 Griffin Rd, Unit C
    CONDOMINIUM OFFICES
    4,570 SF
    Estimated value
    $1,055,000
    Unit C

    100 Griffin Rd, Portsmouth, NH 03801-7158

    View details
    81 Nh Ave
    CONDOMINIUM OFFICES
    15,387 SF
    Estimated value
    $4,595,000

    81 Nh Ave, Portsmouth, NH 03801-2864

    View details

    Portsmouth, NH Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Portsmouth, NH, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 11,282 square feet of properties for sale, with an estimated market value of $3,569,160.

    Sale prices for office spaces in Portsmouth, NH start at $94,160, averaging $594,860, and reaching up to $1,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 89
    Office buildings 9
    Medical Office Space 8
    Creative space 3
    Coworking space 1

    Property Size Breakdown

    The majority of commercial real estate listings in Portsmouth fall within the 100,000+ square foot range.

    Demographics Overview

    Population 23K
    Population Growth (5Y) +2.9%
    Median Household Income $106,520
    College Educated 17.1%

    High-Yield Neighborhoods for Investment

    Identify Portsmouth submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    03801 $1.4M

    Taxes & Financing

    Tax Rate (average for all types) 1.49%
    Property Tax per SF $10.47 per sq ft
    Tax Rate vs County Average 0.23 pp below county avg
    Average Loan-to-Value 65.0%

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