Portsmouth, NH Commercial Real Estate for Lease

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109 properties
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Restaurant Space in Former Bank Building
Updated: May 12
Restaurant Space in Former Bank Building

22 Market Square, Portsmouth, NH 03801

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Iconic former bank building in Portsmouth’s Market Square, previously an Irish pub
Year built: 1803
Restaurant seating for 165 plus outdoor dining
Water source: public
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Highly Visible Retail/Office Space
Updated: May 12
Highly Visible Retail/Office Space

21 Daniel Street, Portsmouth, NH 03801

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Highly visible retail or office space just off Market Square
1,714 SF on the first floor plus 528 SF in the basement
Built in 1800
Water source: public
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Second-Floor Office Suite
Second-Floor Office Suite

26 Market Square, Portsmouth, NH 03801

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Second-floor office overlooking Market Square in a CD5-zoned Portsmouth location.

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Two-Story Retail and Office Suite
Two-Story Retail and Office Suite

72 Mirona Rd Suite 2, Portsmouth, NH 03801

$17 SF/Yr
3,331 sqft

Two-story space with on-site parking and flexible layout for retail or office operations.

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Flex Warehouse with Overhead Access
Flex Warehouse with Overhead Access

620 Peverly Hill Road, Portsmouth, NH 03801

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Open first-floor space with multiple entrances and overhead door access, suited for office, retail, or distribution use.

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Portsmouth Commercial Space For Lease
Portsmouth Commercial Space For Lease

500 Maplewood Ave, Portsmouth, NH 03801

$11/Mo
3,921 sqft

Commercial space with overhead doors, near Interstate 95.

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Two-Story Office Building
Two-Story Office Building

500 Maplewood Ave, Portsmouth, NH 03801

$10/Mo
8,202 sqft

Two-floor office layout with multiple private offices and an unfinished second level for expansion or storage.

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Downtown Office Suites
Downtown Office Suites

25 Chestnut Street, Portsmouth, NH 03801

$20 SF/Yr
5,793 sqft

Two move-in ready office suites with efficient floor plans and excellent natural light in Downtown Portsmouth.

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Shared Office Suite with Waiting Area
Shared Office Suite with Waiting Area

1 Greenleaf Woods Drive, Portsmouth, NH 03801

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Shared office suite with kitchenette, waiting area, and a shared restroom with shower, suited for medical or general office use.

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Shared Office Suite with Waiting Area
Shared Office Suite with Waiting Area

1 Greenleaf Woods Drive, Portsmouth, NH 03801

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Three-room shared office suite with kitchenette and a dedicated waiting area, well suited for client-facing teams.

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Portsmouth Office Space For Lease
Portsmouth Office Space For Lease

500 Maplewood Ave Unit A, Portsmouth, NH 03801

$10 SF/Yr
3,921 sqft

Versatile office space in Portsmouth, accessible from city or bypass.

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Shared Office Suite with Shower
Shared Office Suite with Shower

1 Greenleaf Woods Drive, Portsmouth, NH 03801

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Shared office suite with restroom/shower access, kitchenette, and waiting area in a central Portsmouth setting.

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Shared Medical Office Suite
Shared Medical Office Suite

1 Greenleaf Woods Drive, Portsmouth, NH 03801

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Shared office suite with a waiting area and shared restroom with shower, kitchenette, and central access to major routes.

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Industrial-Flex Warehouse Suite
Industrial-Flex Warehouse Suite

3-270 West Rd, Portsmouth, NH 03801

$15 SF/Yr
4,994 sqft

Industrial and flex space with warehouse area, private offices, and high ceilings for efficient operations.

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Downtown Third-Floor Office Suite
Downtown Third-Floor Office Suite

159 Middle Street, Portsmouth, NH 03801

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Third-floor walk-up office suite with heat, electric, and common-area cleaning included, plus parking and a kitchenette.

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Office/Retail Space Off Walkway
Office/Retail Space Off Walkway

21A Daniel Street, Portsmouth, NH 03801

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Mixed office and retail space available near Buckley’s Market for professional storefront or services use.

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Downtown Office or Retail Space
Downtown Office or Retail Space

66 State Street, Portsmouth, NH 03801

$2,500/Mo
595 sqft

Flexible 595± SF storefront-ready space on State Street with downtown pedestrian activity and consistent vehicular traffic.

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Street-Level Retail Space with Parking
Street-Level Retail Space with Parking

821 Islington Street, Portsmouth, NH 03801

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Street-level storefront with an open retail layout and on-site parking, suited for retail, boutique, studio, or service use.

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Second-Floor Office Suite
Second-Floor Office Suite

96 Penhallow Street, Portsmouth, NH 03801

$3,700/Mo
1,300 sqft

Historic downtown office suite with private restroom and shared patio access, available immediately.

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High-Traffic Retail Site
High-Traffic Retail Site

2299 Lafayette Road, Portsmouth, NH 03801

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7,000 SF retail space with 42 dedicated parking spaces along a high-visibility Portsmouth corridor for a range of storefront uses.

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Second-Floor Office Suite
Second-Floor Office Suite

96-98 Penhallow St, Portsmouth, NH 03801

$3,700/Mo
1,300 sqft

Historic downtown office with a private restroom, shared patio access, and exterior signage rights.

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Renovated Office Suites Above Retail
Renovated Office Suites Above Retail

10 Vaughan, Portsmouth, NH 03801

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Three recently renovated office suites above active street-level tenants, with flexible layouts and potential to combine spaces.

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Highly Visible Retail/Office Suite
Highly Visible Retail/Office Suite

21 Daniel Street, Portsmouth, NH 03801

$6,750/Mo
2,242 sqft

First-floor retail or office space with an added basement area, located just off Market Square for strong visibility.

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Downtown Office Suites Above Retail
Downtown Office Suites Above Retail

10 Vaughan, Portsmouth, NH 03801

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Three recently renovated office suites with high ceilings and flexible layouts are available above street-level retail.

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Portsmouth, NH Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Portsmouth, NH with 109 listings featured on our commercial real estate exchange. The current inventory includes 446,048 square feet of properties with an estimated lease value of $1,055 /Mo.

Estimated lease rates for Commercial real estate in Portsmouth, NH begin at $0.58 SF/Yr, with an average of $21 SF/Yr and extend to $140.73 SF/Yr.
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