Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent / SF / Yr
    $
    $
    Rent / Mo
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Portsmouth, NH Commercial Real Estate for Lease

    List
    Map
    Manchester, NH Nashua, NH Concord, NH
    67 results
    Prime Retail Space on Route 1
    Contact for pricing

    Prime Retail Space on Route 1

    2299 Lafayette Road, Portsmouth, NH 03801

    7,000 SF retail space in high-visibility Portsmouth location.

    • High‑visibility location on Route 1 with ~16,000 vehicles per day.
    • 42 dedicated parking spaces.
    • Located in a high‑traffic commercial corridor surrounded by major national brands (Taco Bell, Common Man Roadside, Walmart).
    • Competitive lease rate.
    • Significant residential growth in the area driving increased demand.
    Updated: Jan 20
    View details
    Shared Office Space in Portsmouth
    Contact for pricing

    Shared Office Space in Portsmouth

    1 Greenleaf Woods Drive, Portsmouth, NH 03801

    Shared office space with central location and highway access.

    • Central location with easy access to downtown Portsmouth, Route 1, and major highways.
    • Shared amenities include a restroom with shower, kitchenette, and waiting area.
    • Suitable for office use.
    • Shared office space.
    • Year Built: 1987.
    Updated: Apr 18
    View details
    Downtown Portsmouth Modern Office Space
    Contact for pricing

    Downtown Portsmouth Modern Office Space

    Modern office space in downtown Portsmouth with parking and amenities.

    299 Hanover Street, Portsmouth, NH 03801
    View details
    Shared Office Space in Portsmouth
    Contact for pricing

    Shared Office Space in Portsmouth

    Shared office space with central location and great proximity.

    1 Greenleaf Woods Drive, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office For Lease
    Contact for pricing

    Downtown Portsmouth Office For Lease

    Office space for lease in downtown Portsmouth, available immediately.

    159 Middle Street, Portsmouth, NH 03801
    View details
    Retail/Office Space in Portsmouth
    Contact for pricing

    Retail/Office Space in Portsmouth

    Updated retail/office space with patio in Portsmouth's North End.

    33 Deer Street, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.

    10 Vaughan, Portsmouth, NH 03801
    View details
    Retail Space in Portsmouth, NH
    Contact for pricing

    Retail Space in Portsmouth, NH

    Retail space for lease in Portsmouth's West End.

    821 Islington Street, Portsmouth, NH 03801
    View details
    Retail/Office Space For Lease
    $17 SF/Yr
    4,100 SF

    Retail/Office Space For Lease

    Retail/office space with ample parking and convenient highway access.

    72 Mirona Rd, Portsmouth, NH
    View details
    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    Versatile office space available for lease in Portsmouth, New Hampshire.

    500 Maplewood Ave unit: A, Portsmouth, NH 03801
    View details
    Portsmouth Commercial Space For Lease
    $11 SF/Yr
    3,921 SF

    Portsmouth Commercial Space For Lease

    Commercial space with overhead doors, near Interstate 95.

    500 Maplewood Ave unit: B, Portsmouth, NH 03801
    View details
    First-Class Office Space Available
    $14 SF/Yr
    5,257 SF

    First-Class Office Space Available

    First-class office space with panoramic views and central location.

    15 Rye St, Portsmouth, NH
    View details
    Modern Office Space Available
    $24 SF/Yr
    3,679 SF

    Modern Office Space Available

    Contemporary office space in premier business corridor, available April 2026.

    75 Portsmouth Blvd, Portsmouth, NH
    View details
    High-End Office Space Available
    $40 SF/Yr
    10,524 SF

    High-End Office Space Available

    Office space with river views in desirable Portsmouth location.

    1 Harbour Place, Portsmouth, NH
    View details
    Commercial For Lease - Portsmouth, NH
    Contact for pricing

    Commercial For Lease - Portsmouth, NH

    Office Units

    1 Greenleaf Woods Drive, Portsmouth, NH 03801
    View details
    Portsmouth Office Space For Lease
    Contact for pricing

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.

    500 Maplewood Avenue, Portsmouth, NH 03801
    View details
    Turnkey Tire Shop on Route 1
    Contact for pricing

    Turnkey Tire Shop on Route 1

    High-volume tire shop for lease near I-95 in Portsmouth.

    500 Maplewood Avenue, Portsmouth, NH 03801
    View details
    Office Space Sublease Opportunity
    Contact for pricing
    6,000 SF

    Office Space Sublease Opportunity

    6,000 SF office space available for sublease.

    2 International Dr, Portsmouth, NH 3801
    View details
    Office Space Near Downtown Portsmouth
    $19 SF/Yr
    10,244 SF

    Office Space Near Downtown Portsmouth

    Office spaces with natural light and convenient location near I-95.

    135 Commerce Way, Portsmouth, NH
    View details
    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF

    Office or Medical Office Space

    Office or medical space in Portsmouth's Pease Tradeport.

    14 Manchester Square, Portsmouth, NH
    View details
    Retail Space in Portsmouth, NH
    Contact for pricing

    Retail Space in Portsmouth, NH

    In-line retail space available in a busy shopping center.

    1465 Woodbury Ave, Portsmouth, NH 3801
    View details

    Portsmouth, NH Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Portsmouth, NH with 67 listings featured on our commercial real estate exchange. The current inventory includes 251,760 square feet of properties with an estimated lease value of $417 /Mo.

    Estimated lease rates for Commercial real estate in Portsmouth, NH begin at $10 SF/Yr, with an average of $18 SF/Yr and extend to $40 SF/Yr.
    List
    Map

    Browse Commercial real estate for Lease Near Portsmouth, NH

    Popular Searches in Portsmouth, NH

    Popular Categories

    Most Searched ZIP Codes in Portsmouth, NH

    • 03801

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!