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    Scott County, MO Commercial Real Estate for Sale

    91 results
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    Sikeston Commercial Property with Duplex
    $320,000
    4,244 SF

    Sikeston Commercial Property with Duplex

    101-103 Donald Fulton Dr, Sikeston, MO 63801

    Commercial building, duplex, and storage on a large lot.

    • Large 3124 sq ft commercial building suitable for various businesses.
    • Income‑generating duplex with both sides currently rented.
    • Additional 900 sq ft storage building.
    • Concrete parking area.
    • Property is enclosed by a 6' chain link fence with two sliding gates.
    Updated: Jan 20
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    Sikeston Fourplex with Income Potential
    $360,000
    0.26 Acres

    Sikeston Fourplex with Income Potential

    416 Lake St, Sikeston, MO 63801

    Fourplex in Sikeston, MO with long-term tenants and income potential.

    • Four‑plex townhouse ideal for investment portfolio or new investors.
    • New roof installed December 2025.
    • Unit 718 fully renovated in January 2026.
    • Three long‑term tenants already in place.
    • Coin‑operated washer/dryer provides additional income.
    Updated: Jan 9
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    Sikeston Car Wash with Expansion Potential
    $1,000,000
    40,511 SF

    Sikeston Car Wash with Expansion Potential

    Turnkey car wash with expansion potential in high-demand market.

    531 N Main St, Sikeston, MO 63780
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    Sikeston Carwash with High Visibility
    $1,250,000
    40,946 SF

    Sikeston Carwash with High Visibility

    Turnkey carwash with high traffic, visibility, and recurring revenue.

    900 S Main St, Sikeston, MO 63801
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    Sikeston Commercial Property For Sale
    $650,000
    1.28 Acres

    Sikeston Commercial Property For Sale

    Prime commercial location with high visibility and established business history.

    1105 S Main St, Sikeston, MO 63801
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    Historical Building in Downtown Sikeston
    $269,000
    6,321 SF

    Historical Building in Downtown Sikeston

    Two-story historic building in downtown Sikeston, ideal for investors.

    112 Front St, Sikeston, MO 63801
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    Historic Downtown Sikeston Retail Opportunity
    $299,000
    14,642 SF

    Historic Downtown Sikeston Retail Opportunity

    Two-story retail space in historic downtown Sikeston, Missouri.

    124 E Front St, Sikeston, MO 63801
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    Sikeston Retail Property For Sale
    $550,000
    1,150 SF

    Sikeston Retail Property For Sale

    Established family-owned business with high visibility for over 30 years.

    1018 Linn St, Sikeston, MO 63801
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    Sikeston Industrial Warehouse on 8+ Acres
    $350,000
    10,000 SF

    Sikeston Industrial Warehouse on 8+ Acres

    Industrial warehouse with I-55 frontage, ideal for logistics or distribution.

    608b State Highway H, Miner, MO 63801
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    Downtown Sikeston Commercial Office Building
    $279,000
    4,273 SF

    Downtown Sikeston Commercial Office Building

    Commercial property with endless business opportunities in downtown Sikeston.

    202 S Kingshighway St, Sikeston, MO 63801
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    Sikeston Warehouse with Highway Access
    $1,100,000
    24,700 SF

    Sikeston Warehouse with Highway Access

    Large warehouse with easy access to I-55 and I-57.

    300 Matthews Ln, Sikeston, MO 63801
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    Sikeston Commercial Property For Sale
    $600,000
    1.30 Acres

    Sikeston Commercial Property For Sale

    Income-producing property with commercial spaces and storage units.

    2008 N Main St, Sikeston, MO 63801
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    Retail Property in Benton, MO
    $145,000
    0.70 Acres

    Retail Property in Benton, MO

    Retail property available for sale in Benton, Missouri.

    1879 County Highway 403, Benton, MO 63736
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    Spacious Home on Large Lot
    $114,900

    Spacious Home on Large Lot

    Three-bedroom home on a 1/3 acre lot.

    703 Cape St, Scott City, MO 63780
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    Sikeston Commercial Building - High Traffic!
    $400,000
    0.74 Acres

    Sikeston Commercial Building - High Traffic!

    7100 sq ft, Multi-Suite, High Traffic Area

    1218 Linn St, Sikeston, MO 63801
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    Sikeston Commercial Property - 5 Acres
    $485,000
    5.00 Acres

    Sikeston Commercial Property - 5 Acres

    Prime 5-acre commercial lot, versatile building.

    714 State Highway H, Sikeston, MO 63801
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    Sikeston Commercial Property: Prime Location
    $450,000
    1.24 Acres

    Sikeston Commercial Property: Prime Location

    Historic Church & Multi-Purpose Building

    306 Kingshighway St, Sikeston, MO 63801
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    Benton Restaurant - Turnkey Opportunity
    $599,900
    0.14 Acres

    Benton Restaurant - Turnkey Opportunity

    Thriving restaurant, prime location, high visibility.

    25 Tywappity St, Benton, MO 63736
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    Sikeston Commercial Property - High Income Potential
    $565,000
    1.28 Acres

    Sikeston Commercial Property - High Income Potential

    Versatile Commercial Building w/ Apartment & Billboard Income

    475 Western Dr, Sikeston, MO 63801
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    Sikeston Commercial Building For Sale
    $239,000

    Sikeston Commercial Building For Sale

    Prime Sikeston location, great investment opportunity.

    1637 Malone Ave, Sikeston, MO 63801
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    Sikeston Commercial Building - Huge Potential
    $460,000
    1.80 Acres

    Sikeston Commercial Building - Huge Potential

    Versatile facility, ample parking, leaseback option.

    205 New Madrid St, Sikeston, MO 63801
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    Sikeston Flex Space: Prime Industrial
    $460,000
    19,498 SF

    Sikeston Flex Space: Prime Industrial

    19,498 SF Flex Building, 1.8 Acres

    205 New Madrid St, Sikeston, MO 63801
    View details

    Scott County, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1004 commercial real estate investment opportunities in Scott County, MO with 91 listings featured on our commercial real estate marketplace. The current inventory includes 30,561,698 square feet of properties with an estimated value of $51,614,050.

    Estimated prices for commercial real estate in Scott County, MO begin at $42,500, with an average of $419,626 and extend to $3,960,000.

    In Scott County, MO, current investment values show:

    • Land positioned at $209,127
    • Retail properties measuring $534,794
    • Residential land & home lots assessed at $60,967
    • Individual retail properties calculated at $501,791
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    Browse Commercial real estate for Sale Near Scott, MO

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