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    Scott County, MO Commercial Real Estate for Lease

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    Corner Lot Office Building
    Updated: Feb 5
    Corner Lot Office Building

    202 S Kingshighway Street, Sikeston, MO 63801

    $4,500/Mo
    Downtown Sikeston commercial building at 202 S Kingshighway with 7,638 sq ft gross building area
    Corner lot with 15 parking places, including 2 handicap spaces
    Accessibility features include an accessible approach with ramp and an accessible elevator installed
    Main level includes receptionist area, large open office/cubicle space, 2 separate offices, and 2 restrooms
    Basement access via stairs and elevator from the back entrance, with kitchen break room, 2 restrooms, conference/office, storage, and open cubicle space
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    Warehouse with Dock Doors
    Updated: Jul 9
    Warehouse with Dock Doors

    300 Matthews Lane, Sikeston, MO 63801

    $5,000/Mo
    20,000 SF industrial building with columns in the middle and 25' bays
    18' ceiling height and concrete floor
    Includes 2 dock doors with levelers
    Also features a 12' x 14' overhead door
    Metal siding exterior
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    Multi-Office Retail-Front Suite
    Multi-Office Retail-Front Suite

    912 S Main Street, Sikeston, MO 63801

    $3,625/Mo

    Recently built strip-center suite offers four offices, a kitchenette, and two entrances for businesses serving the public.

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    Versatile Showroom, Office, and Shop
    Versatile Showroom, Office, and Shop

    229 Airport Rd, Scott City, MO 63780

    $12,000/Mo
    8,516 sqft

    8,516 SF building with high visibility and multiple drive-throughs.

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    New Retail/Office Space Available
    New Retail/Office Space Available

    E-600 N Main Street, Sikeston, MO 63801

    $1,950/Mo
    1,300 sqft

    Prime location with high traffic and ample parking.

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    Trucking Terminal with Drive-In Doors
    Trucking Terminal with Drive-In Doors

    328 South Interstate Drive, Sikeston, MO 63801

    $5.75 SF/Yr
    9,234 sqft

    Trucking terminal with offices, shop/warehouse space, gravel off-street parking, and two overhead drive-in doors.

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    Flexible Office Suite with Parking
    Flexible Office Suite with Parking

    C-1226 Linn St, Sikeston, MO 63801

    $1,500/Mo

    Modern office suite with flexible floor plan and ample parking, positioned near a main town intersection for easy access.

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    Heated and Cooled Warehouse Suite
    Heated and Cooled Warehouse Suite

    1107 School Street #B, Sikeston, MO 63801

    $1,000/Mo
    1,500 sqft

    Warehouse suite with a 30-by-50 open layout, 14-foot overhead door, bathroom, and secure gated, fully fenced access.

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    Medical Office Space Sublease
    Medical Office Space Sublease

    1124 N Main Street, Sikeston, MO 63801

    $16.50 SF/Yr
    2,631 sqft

    2,631 SF medical office space available for sublease.

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    Heavy Industrial Flex Building
    Heavy Industrial Flex Building

    410 W Malone Ave, Sikeston, MO 63801

    Contact for pricing
    7,000 sqft

    Flex space with a basement and heavy industrial zoning, suitable for office, distribution, or manufacturing uses.

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    Retail Space in Sikeston, MO
    Retail Space in Sikeston, MO

    925-1077 Malone Ave, Sikeston, MO

    Contact for pricing
    2,900 sqft

    Retail space available in grocery store anchored shopping center.

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    Grocery-Anchored Shopping Center Space
    Grocery-Anchored Shopping Center Space

    925-1077 Malone Ave, Sikeston, MO 63801

    Contact for pricing
    10,295 sqft

    Grocery store anchored shopping center with strong daily traffic along E. Malone/Hwy 62.

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    Based on your search, we've compiled 61 Potential Opportunities for your consideration. Besides 12 Active listings in Scott County, MO, we suggest exploring alternatives. Similar 49 Properties for Sales.

    Similar Spaces for Sale in Scott County, MO

    Consider Similar Space for Sale. We found 49 Spaces matching your search parameters.

    Modern Industrial Building with Office
    Modern Industrial Building with Office

    3046 Nash Rd, Scott City, MO 63780

    $1,480,000
    10,400 sqft 2.31 AC lot

    10,400 SF industrial building with office and warehouse space.

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    Historic Two-Story Downtown Retail Building
    Historic Two-Story Downtown Retail Building

    124 E Front Street, Sikeston, MO 63801

    $275,000
    14,642 sqft 0.22 AC lot

    Two-story retail building built in 1915 with high ceilings and ground-floor leased space.

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    Sikeston Commercial Building Investment Opportunity
    Sikeston Commercial Building Investment Opportunity

    808 E Wakefield Ave, Sikeston, MO 63801

    $979,500
    11,000 sqft

    High-visibility commercial building with income and upside potential.

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    Industrial Flex Building with Drive-In Doors
    Industrial Flex Building with Drive-In Doors

    1705 Main St, Scott City, MO 63780

    $239,900
    4,780 sqft

    Flex industrial building with office area and four overhead drive-in doors, suited for retail or distribution use under C-1 zoning.

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    Flex-Industrial Headquarters Facility
    Flex-Industrial Headquarters Facility

    205 S New Madrid St, Sikeston, MO 63801

    $449,500
    19,498 sqft 1.00 AC lot

    Multi-parcel flex facility combining office infrastructure with a full-length drive-through warehouse for operations and distribution.

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    Retail and Office Building
    Retail and Office Building

    131 W Yoakum Ave, Chaffee, MO 63740

    $145,000
    4,437 sqft

    For sale on W. Yoakum Ave., the building offers professional office space and retail storefront opportunities.

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    Versatile Industrial Property Near I-55
    Versatile Industrial Property Near I-55

    4930 Nash Rd, Scott City, MO 63780

    $2,200,000
    21,600 sqft 3.17 AC lot

    21,600 SF industrial property with multiple buildings and convenient access.

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    Move-In Ready Downtown Storefront
    Move-In Ready Downtown Storefront

    129 W Yoakum Ave, Chaffee, MO 63740

    $150,000
    2,279 sqft

    Charming downtown storefront offers 2,279 move-in-ready square feet with visibility and easy access on W. Yoakum Ave.

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    Prime Land I-55 Exit 69
    Prime Land I-55 Exit 69

    2338 South Acres Drive, Sikeston, MO 63801

    $1,200,000
    994,910 sqft 22.84 AC lot

    High-traffic vacant land suitable for retail or restaurant development.

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    Remodeled Professional Office Building
    Remodeled Professional Office Building

    210 S Kingshighway Street, Sikeston, MO 63801

    $775,000
    1.67 AC lot

    Remodeled office building with multiple entrances, parking on three sides, and new life-safety systems.

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    Turnkey Restaurant Opportunity in Benton
    Turnkey Restaurant Opportunity in Benton

    25 W Tywappity St., Benton, MO 63736

    $499,000
    2,215 sqft

    Thriving restaurant business with building for sale in Benton, MO.

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    Vacant Land Off Interstate Exit
    Vacant Land Off Interstate Exit

    2338 S Acres Drive, Sikeston, MO 63801

    $1,200,000
    22.84 AC lot

    Vacant ground totaling 22+ acres in Agricultural zoning, positioned just off an I-55 north exit for high-exposure development.

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    Scott County, MO Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Scott County, MO with 12 listings featured on our commercial real estate exchange. The current inventory includes 23,181 square feet of properties with an estimated lease value of $65.16 SF/Yr.

    Estimated lease rates for Commercial real estate in Scott County, MO begin at $5.75 SF/Yr, with an average of $13.03 SF/Yr and extend to $18 SF/Yr.
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