Perryville, MO Commercial real estate for sale

$300,000

4,040 SF

Downtown Perryville Commercial Building

19 S Jackson Street, Perryville, MO 63775

Mixed-use commercial building with income potential in downtown Perryville.

Prime downtown corner‑lot location with HIGH STREET VISIBILITY.
4 rentable units offering EXCELLENT INCOME‑GENERATING POTENTIAL.
Full 4040 +/- sq. ft. walk‑out basement suitable for storage, expansion, or additional rental income.
Convenient street parking plus extra parking at the basement level.
Suitable for professional offices, boutique retail, or mixed‑use tenants.

Updated: Apr 1

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$560,000

3,143 SF

Turnkey Perryville Hospitality Property

221 W Saint Joseph Street, Perryville, MO 63775

Fully operational venue suitable for Airbnb, B&B, or events.

Turn‑key, fully operational business with versatile venue potential (Airbnb, B&B, corporate retreats, events).
Six beautifully appointed bedrooms and four and a half bathrooms provide ample guest accommodations.
Commercial‑grade kitchen with stainless steel appliances supports culinary experiences and catered events.
All furniture included (antique furnishings, bedroom suites, dining room suites).
Ideal for hosting a wide range of events (bridal showers, baby showers, birthdays, intimate gatherings).

Updated: Dec 17, 2025

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$625,000

1,350 SF

Secluded Farm with Pond and Shop

43-acre retreat with stocked pond, tillable acreage, shop/residence.

1770/1771 Pcr 624, Perryville, MO 63775

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$550,000

0.72 Acres

Downtown Perryville Commercial Property

Established commercial property with tenant in place in downtown Perryville.

304 W South Street, Perryville, MO 63775

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$972,000

1,092 SF

Prime Commercial Land, Perryville, MO

0.94 acre commercial land with high traffic and development potential.

1324 W Saint Joseph Street, Perryville, MO 63775

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$131,000

0.23 Acres

Turnkey Day Care Facility

Ready-to-go day care with playground and equipment included.

500 W North Street, Perryville, MO 63775

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$607,464

9.36 Acres

Commercial Land with High Visibility

9.36 acres of commercial land with development potential.

1 Perryville Boulevard, Perryville, MO 63775

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$607,464

9.36 Acres

Prime Commercial Land For Sale

9.36 acres of commercial land with high traffic visibility.

1 Perryville Boulevard, Perryville, MO 63775

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Mixed-Use Property in Downtown Perryville

$3,030,000

20,600 SF

Mixed-Use Property in Downtown Perryville

Multi-tenant property with residential and commercial units in downtown Perryville.

104-110 N Jackson Street, Perryville, MO 63775

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$209,500

1.00 Acre

Perryville Commercial Land Opportunity

Highly visible commercial land near the interstate, ideal for development.

7971 Hwy B, Perryville, MO 63775

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$220,000

8.80 Acres

Hilltop Land with Steel Buildings

8.8 acres with steel buildings and utility access in Perryville.

1744 PCR 710, Perryville, MO 63775

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$87,900

0.73 Acres

Lake Perry Community Camp Lot

Camp lot with lake views and community amenities.

1036 Erie Trail Drive, Perryville, MO 63775

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$695,000

Fully Rehabbed Mixed-Use Building

Fully rehabbed mixed-use building with parking and a flexible interior for retail, events, or dining.

119 N Jackson Street, Perryville, MO 63775

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$350,000

11,500 SF

Perryville Commercial Property For Sale

Flexible commercial property with shop and office in high-traffic location.

1205 S Kingshighway St, Perryville, MO 63775

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$753,000

Warehouse For Sale

For sale industrial warehouse in Perry County, with GPS-friendly directions for straightforward access.

1004 N Main Street, Perryville, MO 63775

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$134,900

Vacant Retail/Office Building

Vacant building sold as-is, positioned for exposure along a major highway corridor in Perryville.

704 Kingshighway St, Perryville, MO 63775

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$493,888

1.63 Acres

Commercially Zoned Land with Income

1.63 acres with income-producing water and ice vending business.

351 N Perryville Blvd, Perryville, MO 63775

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$2,803,000

2,443 SF

New Starbucks with Drive-Thru

New construction Starbucks with drive-thru and outdoor patio.

1111 S Perryville Blvd, Perryville, MO

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$300,000

Storefront Retail Property

For sale storefront retail property located in Perryville, Missouri.

19 S Jackson Street, Perryville, MO 63775

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Contact for pricing

85,975 SF

Retail Shopping Center

For sale shopping center with gross rents cited at $3.85/SF and major employers within one mile.

108 Perry Plaza, Perryville, MO 63775

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$948,945

6,721,308 SF

Perry County Land with Timber

154.3 acre property with timber and recreational opportunities.

210 Pcr 210, Perryville, MO 63775

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Highway Visible Commercial Land For Sale

$649,900

17.38 Acres

Highway Visible Commercial Land For Sale

Flat, highway-visible land zoned C-2, suitable for various commercial uses.

1100 Cinque Hommes Drive, Perryville, MO 63775

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$95,200

259,182 SF

Land for Hunting/Hobby Farm

Land suitable for hunting, hobby farm, or building site.

Lot #2 Pcr 910, Perryville, MO 63775

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Prime Commercial Development Opportunity

$972,000

1,092 SF

Prime Commercial Development Opportunity

0.94 acre commercial land with high traffic location.

1324 W Saint Joseph Street, Perryville, MO 63775

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Perryville, MO Commercial Real Estate Investment Opportunities Market Analysis

Explore 72 commercial real estate for sale in Perryville, MO, showcased through 29 active listings on our real estate platform. These investment opportunities span a total of 7,025,750 square feet of properties for sale, with an estimated market value of $10,656,145.

Sale prices for business properties in Perryville, MO start at $95,200, averaging $1,065,614, and reaching up to $3,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
63775	$598.5K

Neighborhood

Average Price

63775

$598.5K