Perryville, MO Commercial Real Estate for Sale

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28 properties

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Updated: Jun 26

Renovated Downtown Bar and Event Venue

15 W Saint Joseph Street, Perryville, MO 63775

$699,900

0.12 AC lot

Renovated bar and event venue at 15 W Saint Joseph Street, Perryville, MO 63775
0.12‑acre property on Perryville’s historic downtown square
Industrial kitchen with walk‑in freezer and commercial cooking equipment
Expansive basement with completed architectural plans for renovation
Brick building constructed in 1932

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Updated: Sep 18

Drive-Through Restaurant with Business

117 S Kingshighway Street, Perryville, MO 63775

$490,500

0.36 AC lot

Operating drive‑through restaurant with real estate, equipment, and business included
Established menu featuring burgers, fries, frozen custard, and additional items
Located at 117 S Kingshighway Street, Perryville, MO 63775
Situated on approximately 0.356 acres
1988 building with brick construction

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Office Building with Attached Garage

875 PCR 500, Perryville, MO 63775

$745,000

5.16 AC lot

Flexible office property with dedicated work areas, support spaces, outbuildings, and solar panels on acreage outside city limits.

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Warehouse with Overhead Doors

1004- B N Main, Perryville, MO 63775

$325,000

6,000 sqft 1.00 AC lot

Configured for equipment, fleet, RV, and contractor storage with heated, electrically serviced enclosed bays.

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C-2 Commercial Land with Frontage

1324 W Saint Joseph Street, Perryville, MO 63775

$972,000

1,092 sqft 0.94 AC lot

C-2 commercial land with public water, public sewer, and completed site improvements.

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Remodeled Flex Space

805 N Main Street, Perryville, MO 63775

$235,000

0.19 AC lot

Updated commercial space with storefront presentation, dedicated parking, and adaptable interior improvements for business operations.

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Two-Level Day Care Center

4 Kiefner Street, Perryville, MO 63775

$335,000

0.36 AC lot

Updated two-level facility with an established childcare layout and flexible upper-floor space, subject to applicable approvals.

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Self-Storage Facility with Open Bays

1004-B North Main Street, Perryville, MO 63775

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6,000 sqft 1.00 AC lot

The 2018 building includes enclosed and open storage areas, with heat and electric serving two leased bays.

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Tenant-Occupied Bowling Alley

304 W South Street, Perryville, MO 63775

$550,000

0.72 AC lot

Brick bowling facility with tenant occupancy, public water service, and central air conditioning.

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Brick Bed & Breakfast with Event Space

221 W Saint Joseph Street, Perryville, MO 63775

$560,000

0.37 AC lot

Hospitality property with guest accommodations, event functionality, and a stainless-steel-equipped kitchen.

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Absolute NNN Industrial Property

50 Robinson Industrial Drive, Perryville, MO 63775

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51,580 sqft 48.26 AC lot

Fully leased industrial asset with an absolute NNN structure and planned manufacturing expansion.

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Multi-Tenant Mixed-Use Property

104-110 N Jackson Street, Perryville, MO 63775

$3,030,000

0.09 AC lot

Includes leased commercial space and residential units with both short- and long-term occupancy.

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Commercial Land Near Interstate

7971 Hwy B, Perryville, MO 63775

$199,000

Commercial land with electricity available near an interstate exit.

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Mixed-Use Multifamily and Retail Building

110-104 N Jackson St, Perryville, MO 63775

$3,030,000

20,000 sqft

Mixed-use property with eight residential units and four leased commercial storefronts, totaling over 20,000 square feet.

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Flex Space with Separate Office

1205 N Kingshighway St, Perryville, MO 63775

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13,134 sqft

Flex property combines a large shop with a separate office building for operational and administrative functions.

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Renovated Event Venue and Bar

15 W Saint Joseph St, Perryville, MO 63775

$699,900

Renovated event venue and bar with a fully equipped industrial kitchen, walk-in freezer, and flexible spaces.

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Commercial Land Near Interstate

7971 HWY B, Perryville, MO 63775

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3,065 sqft

Commercially zoned land with electric availability near an interstate exit and access from HWY B.

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Warehouse For Sale

1004 N Main Street, Perryville, MO 63775

$753,000

For sale industrial warehouse in Perry County, with GPS-friendly directions for straightforward access.

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Commercial Land with City Utilities

1 Perryville Blvd, Perryville, MO 63775

$607,464

A 9.36-acre development parcel with city-street access and available municipal utilities.

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Turnkey Historic Brick Office Building

23/25/27 W Saint Joseph St, Perryville, MO 63775

$1,150,000

Fully restored 1859 brick building with updated HVAC including central air and mini-splits, plus multiple income-producing spaces.

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Unrestricted Agricultural Land Tract

914 Off Pcr, Perryville, MO 63775

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9.06 AC lot

Approximately 9.06 acres of unrestricted land off County Road 914 with electric along the road and nearby public water access.

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Warehouse with Dock Access

628 Old Saint Marys Rd (Rear), Perryville, MO 63775

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Warehouse space with dock and drive-in access, signage opportunities, and off-street parking in a neighborhood retail center.

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Class A Professional Office Plaza

1304-1310 Brenda Ave., Perryville, MO 63775

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Professional office units in a Class A plaza with off-street parking and backlit monument signage.

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Jefferson Street Commercial Space Available

2015 - 2021 Jefferson Street, Perryville, MO 63775

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Commercial space for rent on Jefferson Street, Perryville, MO.

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Perryville, MO Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Perryville, MO, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 100,871 square feet of properties for sale, with an estimated market value of $14,381,764.

Sale prices for business properties in Perryville, MO start at $199,000, averaging $898,860, and reaching up to $3,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 17K

Population Growth (5Y) +21.1%

Median Household Income $65,171

College Educated 18.7%

High-Yield Neighborhoods for Investment

Identify Perryville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
63775	$697.4K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Cape Girardeau County

New Delisted

Total CRE Inventory on Market (SF)

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