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    Perryville, MO
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    Perryville, MO Retail Properties & Spaces for Sale

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    Corner Commercial Land with Road Frontage
    Updated: Oct 16, 2025
    Corner Commercial Land with Road Frontage

    1324 W Saint Joseph Street, Perryville, MO 63775

    $972,000
    1,092 sqft 0.94 AC lot
    .94‑acre commercial development site with 180 ft of road frontage and appropriate ingress/egress access
    Zoned C‑2 in a high‑traffic corner location with easy access to I‑55 and downtown Perryville
    Value‑added site improvements already completed to a ready standard for build‑to‑suit or custom prospects
    Located near established businesses including Walgreens, Scooter's Coffee, Duke Veterinary Clinic, and Perryville Tire
    Utilities include public water and public sewer; cable available
    View details
    Day Care with Flexible Upper Space
    Updated: Jul 10
    Day Care with Flexible Upper Space

    4 Kiefner St, Perryville, MO 63775

    $350,000
    4,000 sqft
    Over 4,000 SF commercial property currently operating as a daycare with flexible interior space
    Main level designed for childcare with room for classrooms, learning stations, indoor activities, and play areas
    Upper level offers flexibility to live on‑site, create office space, or expand licensed childcare capacity (subject to licensing)
    Improvements within the last five years include new windows, updated HVAC, and a new roof over the flat portion
    Several additional updates completed within the past two years
    View details
    Mixed-Use Multifamily and Retail Building
    Mixed-Use Multifamily and Retail Building

    110-104 N Jackson St, Perryville, MO 63775

    $3,030,000
    20,000 sqft

    Mixed-use property with eight residential units and four leased commercial storefronts, totaling over 20,000 square feet.

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    Commercially Zoned Land with Income
    Commercially Zoned Land with Income

    351 N Perryville Blvd, Perryville, MO 63775

    $443,888
    1.63 AC lot

    1.63 acres with income-producing water and ice vending business.

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    Vacant Retail/Office Building
    Vacant Retail/Office Building

    704 Kingshighway St, Perryville, MO 63775

    $134,900

    Vacant building sold as-is, positioned for exposure along a major highway corridor in Perryville.

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    Prime Commercial Development Opportunity
    Prime Commercial Development Opportunity

    1324 W Saint Joseph Street, Perryville, MO 63775

    $972,000
    1,092 sqft 0.94 AC lot

    0.94 acre commercial land with high traffic location.

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    Storefront Retail Property
    Storefront Retail Property

    19 S Jackson Street, Perryville, MO 63775

    $300,000

    For sale storefront retail property located in Perryville, Missouri.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 7 Active listings in Perryville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Former Ford Dealership with Service Bays
    Former Ford Dealership with Service Bays

    610 Sainte Genevieve Dr, Ste Genevieve, MO 63670

    $1,900,000
    26,000 sqft 2.52 AC lot

    Hard-corner site with showroom, service bays, parts area, and autobody shop, plus extensive vehicle parking.

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    Mixed-Use Retail and Apartment Building
    Mixed-Use Retail and Apartment Building

    104-106 W Stacey Street, Chester, IL 62233

    $180,000
    0.07 AC lot

    Historic mixed-use building features street-level retail space and five one-bedroom apartments above.

    View details
    Retail Office Showroom Building
    Retail Office Showroom Building

    504 S 4th Street, Ste Genevieve, MO 63670

    $199,900
    3,160 sqft

    Retail office showroom building with an open floor plan and equipment that can convey for a turnkey operation.

    View details
    Historic Mixed-Use Building with Apartments
    Historic Mixed-Use Building with Apartments

    104-106 W Stacey Street, Chester, IL 62233

    $180,000

    Built in 1920, the property offers street-level retail with five upstairs one-bed, one-bath apartments and a full basement with outside access.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Development Land
    Commercial Development Land

    1 Perryville Boulevard, Perryville, MO 63775

    $607,464
    9.36 AC lot

    Zoned C2 commercial land with city utilities available for flexible development planning.

    View details
    Terrace Park Estates Land
    Terrace Park Estates Land

    202-204 West Deerwood Drive, Jackson, MO 63755

    $69,000
    20,211 sqft 0.46 AC lot

    Land in Terrace Park Estates, ready for development.

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    Commercially Zoned Land Parcel
    Commercially Zoned Land Parcel

    202-204 W Deerwood Drive, Jackson, MO 63755

    $69,000
    0.46 AC lot

    Commercially zoned C2 parcel in Jackson, ready for new construction.

    View details
    Commercial Land with Major Road Frontage
    Commercial Land with Major Road Frontage

    Tract 5 off Hwy 72 Bypass, Fredericktown, MO 63645

    $995,000
    54.72 AC lot

    Large commercially zoned tract with utilities onsite, plus extensive Hwy 72 Bypass and river frontage for flexible development.

    View details

    Off-Market Properties in Perryville, MO

    Consider similar Off-Market properties in Perryville, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    406 Perryville Blvd
    FINANCIAL BUILDING

    406 Perryville Blvd, Perryville, MO 63775-1277

    Value Estimation by Request
    6,715 sqft
    View details
    16 Jackson St
    RETAIL STORES (PERSONAL SERVICES)

    16 Jackson St, Perryville, MO 63775-1334

    Value Estimation by Request
    3,600 sqft
    View details
    117 Kingshighway St
    RESTAURANT

    117 Kingshighway St, Perryville, MO 63775-1903

    Value Estimation by Request
    780 sqft 0.40 AC lot
    View details
    300 Main St
    RETAIL STORES (PERSONAL SERVICES)

    300 Main St, Perryville, MO 63775-1316

    Value Estimation by Request
    427 sqft
    View details
    12 Shakertown Hall Ln
    REGIONAL SHOPPING CENTER, MALL

    12 Shakertown Hall Ln, Perryville, MO 63775-9796

    Value Estimation by Request
    3,096 sqft 0.70 AC lot
    View details
    1116 Kingshighway St
    DRIVE-THRU RESTAURANT, FAST FOOD

    1116 Kingshighway St, Perryville, MO 63775-3313

    Value Estimation by Request
    544 sqft 1.20 AC lot
    View details
    5029 Hwy 61
    BAR, TAVERN

    5029 Hwy 61, Perryville, MO 63775-8441

    Value Estimation by Request
    864 sqft 0.20 AC lot
    View details
    712 Kingshighway St
    REGIONAL SHOPPING CENTER, MALL

    712 Kingshighway St, Perryville, MO 63775-1258

    Value Estimation by Request
    2,400 sqft 2.90 AC lot
    View details
    18 Perryville Blvd
    RESTAURANT

    18 Perryville Blvd, Perryville, MO 63775-1267

    Value Estimation by Request
    2,272 sqft 1.20 AC lot
    View details
    605 Saint Joseph St
    RETAIL STORES (PERSONAL SERVICES)

    605 Saint Joseph St, Perryville, MO 63775-1755

    Value Estimation by Request
    1,320 sqft
    View details
    2002 Lk Dr
    RESTAURANT

    2002 Lk Dr, Perryville, MO 63775-9757

    Value Estimation by Request
    4,944 sqft 1.20 AC lot
    View details
    14852 Hwy T T
    BAR, TAVERN

    14852 Hwy T T, Perryville, MO 63775-7730

    Value Estimation by Request
    1,209 sqft 3.10 AC lot
    View details
    701 Perryville Blvd
    VEHICLE SALES, RENTALS

    701 Perryville Blvd, Perryville, MO 63775-2874

    Value Estimation by Request
    1,260 sqft
    View details
    211 Kingshighway St
    RESTAURANT

    211 Kingshighway St, Perryville, MO 63775-1905

    Value Estimation by Request
    2,604 sqft 0.70 AC lot
    View details
    314 Saint Joseph St
    DRIVE-THRU RESTAURANT, FAST FOOD

    314 Saint Joseph St, Perryville, MO 63775-1829

    Value Estimation by Request
    1,890 sqft
    View details
    118 Sainte Marie St
    RETAIL STORES (PERSONAL SERVICES)

    118 Sainte Marie St, Perryville, MO 63775-1349

    Value Estimation by Request
    2,040 sqft
    View details
    2015-2021 Jefferson St
    Neighborhood centers

    2015-2021 Jefferson St, Perryville, MO 63775

    Value Estimation by Request
    9,714 sqft
    View details

    Perryville, MO Retail Properties & Spaces Market Trends and Statistics

    Explore 72 retail properties & spaces for sale in Perryville, MO, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 26,184 square feet of properties for sale, with an estimated market value of $6,202,788.

    Sale prices for stores in Perryville, MO start at $134,900, averaging $886,112, and reaching up to $3,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Storefront properties 4

    Demographics Overview

    Population 17K
    Population Growth (5Y) +21.1%
    Median Household Income $65,171
    College Educated 18.7%

    High-Yield Neighborhoods for Investment

    Identify Perryville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63775 $519.2K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cape Girardeau County

    New Delisted

    Total CRE Inventory on Market (SF)

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