Advertise
    Perryville, MO
    Office

    Perryville, MO Office Spaces for Sale

    Notify Me
    List
    Map
    Daisy, MO Oak Ridge, MO Sedgewickville, MO Frohna, MO Jackson, MO Patton, MO Whitewater, MO Cape Girardeau, MO
    6 properties
    Flex Property with Attached Garage
    Updated: May 17
    Flex Property with Attached Garage

    875 PCR 500, Perryville, MO 63775

    $745,000
    5.16 AC lot
    5.16+/- acres just outside Perryville city limits, with access via newly paved PCR 500
    Main business center built in 1995 with 8 offices, reception area, spacious conference room, kitchen, storage rooms, and product showcase space
    Includes 2 vaults and multiple half bathrooms within the main business center layout
    48x52 attached garage with half bath, electric and furnace, plus overhead doors
    Additional 88x24 outbuilding with gravel floors, electric, 2 enclosed bays, and 1 open lean‑to area
    View details
    Day Care with Flexible Upper Space
    Updated: Jul 10
    Day Care with Flexible Upper Space

    4 Kiefner St, Perryville, MO 63775

    $350,000
    4,000 sqft
    Over 4,000 SF commercial property currently operating as a daycare with flexible interior space
    Main level designed for childcare with room for classrooms, learning stations, indoor activities, and play areas
    Upper level offers flexibility to live on‑site, create office space, or expand licensed childcare capacity (subject to licensing)
    Improvements within the last five years include new windows, updated HVAC, and a new roof over the flat portion
    Several additional updates completed within the past two years
    View details
    Prime Commercial Development Opportunity
    Prime Commercial Development Opportunity

    1324 W Saint Joseph Street, Perryville, MO 63775

    $972,000
    1,092 sqft 0.94 AC lot

    0.94 acre commercial land with high traffic location.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Class A Professional Office Plaza
    Class A Professional Office Plaza

    1304-1310 Brenda Ave., Perryville, MO 63775

    Contact for pricing

    Professional office units in a Class A plaza with off-street parking and backlit monument signage.

    View details
    Turnkey Historic Brick Office Building
    Turnkey Historic Brick Office Building

    23/25/27 W Saint Joseph Street, Perryville, MO 63775

    $1,150,000

    Fully restored 1859 brick building with updated HVAC including central air and mini-splits, plus multiple income-producing spaces.

    View details
    Office Building with Multiple Entrances
    Office Building with Multiple Entrances

    407 W Saint Joseph, Perryville, MO 63775

    $299,000

    Office suite includes reception, kitchen, 1.5 baths, seven private offices, plus three additional rental spaces with separate exterior entrances.

    View details
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 6 Active listings in Perryville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Office Building with Reception Area
    Office Building with Reception Area

    152 S Main, Fredericktown, MO 63645

    $159,000
    1,538 sqft 0.09 AC lot

    Former Fredericktown Vision Center with a reception area and large open space on a small downtown lot.

    View details
    Freestanding Office Redevelopment Building
    Freestanding Office Redevelopment Building

    208 Lincoln Dr, Fredericktown, MO 63645

    Contact for pricing
    23,166 sqft 1.62 AC lot

    Vacant, 23,166 SF freestanding all-brick office building on 1.62 acres, built in 1981 and ready for redevelopment.

    View details
    Retail Office Showroom Building
    Retail Office Showroom Building

    504 S 4th Street, Ste Genevieve, MO 63670

    $199,900
    3,160 sqft

    Retail office showroom building with an open floor plan and equipment that can convey for a turnkey operation.

    View details
    Prime Location Retail/Office/Showroom Building
    Prime Location Retail/Office/Showroom Building

    Ste Genevieve, MO 63670

    Contact for pricing
    3,160 sqft

    High-traffic location with flexible space for business or investment.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Corner Commercial Land with Road Frontage
    Corner Commercial Land with Road Frontage

    1324 W Saint Joseph Street, Perryville, MO 63775

    $972,000
    1,092 sqft 0.94 AC lot

    Zoned C-2 commercial land with 180 feet of road frontage and ingress/egress suitable for build-to-suit development.

    View details
    Commercial Development Land
    Commercial Development Land

    1 Perryville Boulevard, Perryville, MO 63775

    $607,464
    9.36 AC lot

    Zoned C2 commercial land with city utilities available for flexible development planning.

    View details
    Commercial Development Land
    Commercial Development Land

    Tract 2 off Emerald Bluff Dr, Fredericktown, MO 63645

    $195,000
    1.84 AC lot

    Nearly two acres of commercial land with three-sided road frontage and utilities available for flexible site development.

    View details
    Commercial Development Lot
    Commercial Development Lot

    540 East Broadway, Sparta, IL 62286

    Contact for pricing

    Zoned commercial land with state highway frontage and convenient access, positioned between two medical facilities.

    View details

    Off-Market Properties in Perryville, MO

    Consider similar Off-Market properties in Perryville, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    123 Spg St
    OFFICE (GENERAL)

    123 Spg St, Perryville, MO 63775-2040

    Value Estimation by Request
    2,341 sqft 0.30 AC lot
    View details
    11 Saint Joseph St
    OFFICE (GENERAL)

    11 Saint Joseph St, Perryville, MO 63775-1344

    Value Estimation by Request
    1,776 sqft
    View details
    102 St
    RADIO OR TV STATION

    102 St, Perryville, MO 63775-2002

    Value Estimation by Request
    View details
    103 Saint Joseph St
    OFFICE (GENERAL)

    103 Saint Joseph St, Perryville, MO 63775-1345

    Value Estimation by Request
    7,912 sqft 0.10 AC lot
    View details
    1508 Edgemont Blvd
    DENTAL BUILDING

    1508 Edgemont Blvd, Perryville, MO 63775-1231

    Value Estimation by Request
    6,408 sqft 1.00 AC lot
    View details
    121 Main St
    DENTAL BUILDING

    121 Main St, Perryville, MO 63775-2524

    Value Estimation by Request
    1,960 sqft
    View details
    624 Old Saint Marys Rd
    OFFICE (GENERAL)

    624 Old Saint Marys Rd, Perryville, MO 63775-1832

    Value Estimation by Request
    4,700 sqft 0.30 AC lot
    View details
    4200 Pcr 806
    OFFICE (GENERAL)

    4200 Pcr 806, Perryville, MO 63775-9187

    Value Estimation by Request
    720 sqft 5.00 AC lot
    View details
    334 Main St
    DENTAL BUILDING

    334 Main St, Perryville, MO 63775-1362

    Value Estimation by Request
    1,470 sqft
    View details
    8 Sainte Marie St
    OFFICE (GENERAL)

    8 Sainte Marie St, Perryville, MO 63775-1347

    Value Estimation by Request
    4,420 sqft
    View details
    108 En St
    OFFICE (GENERAL)

    108 En St, Perryville, MO 63775-2005

    Value Estimation by Request
    600 sqft 0.10 AC lot
    View details
    3146 Hwy 51
    OFFICE (GENERAL)

    3146 Hwy 51, Perryville, MO 63775-7153

    Value Estimation by Request
    144 sqft 1.60 AC lot
    View details
    1426 Kingshighway St
    OFFICE (GENERAL)

    1426 Kingshighway St, Perryville, MO 63775

    Value Estimation by Request
    336 sqft
    View details
    875 Pcr 500
    Office Spaces

    875 Pcr 500, Perryville, MO 63775

    Value Estimation by Request
    6,854 sqft 8.66 AC lot
    View details
    181 Whippoorwill Ln
    RADIO OR TV STATION

    181 Whippoorwill Ln, Perryville, MO 63775-8635

    Value Estimation by Request
    View details
    111 Walnut St
    OFFICE (GENERAL)

    111 Walnut St, Perryville, MO 63775-2000

    Value Estimation by Request
    2,400 sqft
    View details
    315 Smith St
    OFFICE (GENERAL)

    315 Smith St, Perryville, MO 63775-1928

    Value Estimation by Request
    736 sqft
    View details
    Shannie Rd
    RADIO OR TV STATION

    Shannie Rd, Perryville, MO 63775

    Value Estimation by Request
    0.10 AC lot
    View details

    Perryville, MO Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Perryville, MO, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 5,092 square feet of properties for sale, with an estimated market value of $3,516,000.

    Sale prices for office spaces in Perryville, MO start at $299,000, averaging $703,200, and reaching up to $1,150,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 8
    Office buildings 1

    Demographics Overview

    Population 17K
    Population Growth (5Y) +21.1%
    Median Household Income $65,171
    College Educated 18.7%

    High-Yield Neighborhoods for Investment

    Identify Perryville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63775 $485.6K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cape Girardeau County

    New Delisted

    Total CRE Inventory on Market (SF)

    Need Help?

    Reach out if you need assistance with Realmo tools or have questions about your listings

    Contact Us

    Popular Searches in Perryville, MO

    Popular Categories

    Most Searched ZIP Codes in Perryville, MO

    • 63775

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!