Commercial Real Estate Market in Perryville, MO
Updated monthly: sale, lease, property records, location trend, and more… · Last update: August 31
78 active listings and 595 off-market properties in Perryville, MO. Commercial property asks $98/SF to buy and $6.00/SF/Yr to lease.
Market Trends
Perryville, MO spans 363.1 square miles in Cape Girardeau County, Missouri. Figures below refresh monthly; last updated 31 August 2026.
Office
Office vacancy in Perryville, MO runs 21.3% across the Midwest region in 2025, up from 13.7% in 2019.
Vacancy Rate % in Midwest region
Retail
Retail vacancy in Perryville, MO runs 6.3% across the Midwest region in 2025, down from 8% in 2020.
Vacancy Rate % in Midwest region
Industrial
Industrial vacancy in Perryville, MO runs 4.9% across the Midwest region in 2025, up from 4.4% in 2019. Nearly 1.6x the 2022 low of 3.1%.
Vacancy Rate % in Midwest region
Multifamily
Multifamily space in Perryville, MO asks $135/SF to buy. Vacancy runs 8% across the Midwest region in 2025, up from 6.5% in 2022.
Average Sale Price $/SF
Listings
Vacancy Rate % in Midwest region
Zoning & Land Use
Land Use Mix share of zoned land by category
- Residential 69.5%
- Commercial 15.8%
- Industrial 14.7%
Largest Zones share of zoned land by district
Single Family Residential
Single Family Residential
General Commercial
Heavy Industrial
General Residential
Perryville, MO zones 4,722 acres across 10 districts. Commercial zoning covers 15.8% of zoned land, residential 69.5% and industrial 14.7%. The largest single district is Single Family Residential at 37%. For commercial buyers the practical constraint is that only 30.6% of land carries a commercial or industrial designation.
Single Family Residential (R-2)
The purpose of the R-2 single family residential district is to provide for more compact single family housing.
Market overview
Demographics & Economy
Perryville, MO has 16,989 residents in 7,399 households. Density runs 47 people per square mile. Median household income here is $64,537 and median gross rent $925 a month.
16,989
Population
7,399
Households
2.3
Avg Household Size
42
Median Age
21%
College-Educated
88%
High-School Grad
363.1 sq mi
ZIP Area
47
Density / Sq Mi
$64,537
Median Household Income
$36,271
Median Earnings
$925
Median Rent
$192,100
Median Home Value
Tools
Nearby Markets
| Market | Average Sale Price, $/SF | Average Lease Price, $/SF/Yr |
|---|---|---|
| Friedheim | — | — |
| Biehle | — | — |
| Apple Creek | — | — |
| Daisy | — | — |
Commercial property in Perryville, MO asks $98/SF.
Frequently Asked Questions
What is the average price per square foot for commercial property in Perryville?
Commercial property in Perryville, MO asks an average of $98 per square foot. Multifamily carries the highest asking price at $135/SF.
How much does it cost to lease commercial space in Perryville?
Asking lease rates in Perryville, MO average $6.00 per square foot per year.
What zoning applies to commercial property in Perryville?
Perryville, MO zones 4,722 acres across 10 districts, of which 15.8% is commercial and 14.7% industrial. The largest single district is Single Family Residential at 37% of zoned land. The purpose of the R-2 single family residential district is to provide for more compact single family housing. Residential zoning covers 69.5% and open space 0%.
Where does Realmo's Perryville market data come from?
Realmo compiles Perryville, MO figures from 71 active sale listings, 7 active lease listings, 595 tracked off-market properties, the current Perryville zoning release. Sale and lease figures refresh monthly; vacancy annually. Last updated 31 August 2026.
Methodology & data sources
- Asking prices and averages
- Computed from 71 active for-sale and 7 active for-lease listings in Perryville, MO. These are ASKING figures from live listings, not closed-transaction prices, and a segment carried by a handful of listings reads as indicative rather than an average.
- Vacancy rates
- Published per-sector market series, taken at the metro level where one exists and otherwise at the Census-region level — a chart reading "in <region> region" is a regional number, not this city's.
- Zoning and land use
- The current municipal zoning release: 4,722 zoned acres across 10 districts. Shares are of zoned land, so parcels the release leaves unclassified are excluded from the mix.
- Refresh
- The monthly aggregates close at the end of the previous month, so 31 August 2026 — not today — is the honest last update.
- Known limitations
- office vacancy is reported at Midwest region level, retail vacancy is reported at Midwest region level and industrial vacancy is reported at Midwest region level.
- Coverage
- Metrics below the 10-observation threshold fall back one geographic level. The geography used is named on each figure.
Compiled by the Realmo Data team · reviewed 31 August 2026 · report a data issue
