Commercial Real Estate Market in Perryville, MO
Updated monthly: sale, lease, property records, location trend, and more… · Last update: October 31
27 active listings and 594 off-market properties in Perryville, MO.
Market Trends
Perryville, MO spans 363.1 square miles in Cape Girardeau County, Missouri. Figures below refresh monthly; last updated 31 October 2026.
Office
Office vacancy in Perryville, MO runs 21.3% across the Midwest region in 2025, up from 13.7% in 2019.
Retail
Retail vacancy in Perryville, MO runs 6.3% across the Midwest region in 2025, down from 8% in 2020.
Industrial
Industrial vacancy in Perryville, MO runs 4.9% across the Midwest region in 2025, up from 4.4% in 2019. Nearly 1.6x the 2022 low of 3.1%.
Multifamily
Multifamily vacancy in Perryville, MO runs 8% across the Midwest region in 2025, up from 6.5% in 2022.
Zoning & Land Use
Land Use Mix share of zoned land by category
- Residential 69.5%
- Commercial 15.8%
- Industrial 14.7%
Largest Zones share of zoned land by district
Perryville, MO zones 4,722 acres across 10 districts. Commercial zoning covers 15.8% of zoned land, residential 69.5% and industrial 14.7%. The largest single district is Single Family Residential at 37%. For commercial buyers the practical constraint is that only 30.6% of land carries a commercial or industrial designation.
The purpose of the R-2 single family residential district is to provide for more compact single family housing.
Market overview
Demographics & Economy
Perryville, MO has 16,989 residents in 7,399 households. Density runs 47 people per square mile. Median household income here is $64,537 and median gross rent $925 a month.
Tools
Frequently Asked Questions
What is the median price per square foot for commercial property in Perryville?
What zoning applies to commercial property in Perryville?
Where does Realmo's Perryville market data come from?
Methodology & data sources
- Asking prices and medians
- There are 22 active for-sale and 5 active for-lease listings in Perryville, MO. The sale median is based on 5 of the for-sale listings that state a price per square foot; too few for-lease listings state a rent per square foot for a rent median. These are ASKING figures from live listings, not closed-transaction prices, and a figure resting on fewer than 10 listings says so where it is quoted.
- Vacancy rates
- Published per-sector market series, taken at the metro level where one exists and otherwise at the Census-region level — a chart reading "in <region> region" is a regional number, not this city's.
- Zoning and land use
- The current municipal zoning release: 4,722 zoned acres across 10 districts. Shares are of zoned land, so parcels the release leaves unclassified are excluded from the mix.
- Refresh
- The monthly aggregates close at the end of the previous month, so 31 October 2026 — not today — is the honest last update.
- Known limitations
- office vacancy is reported at Midwest region level, retail vacancy is reported at Midwest region level and industrial vacancy is reported at Midwest region level.
- Coverage
- Metrics below the 10-observation threshold fall back one geographic level. The geography used is named on each figure.
Compiled by the Realmo Data team · reviewed 31 October 2026 · How Realmo checks market page data · Report a data issue
