Perryville, MO Office Spaces for Rent & Lease

Updated: Jun 30

Six-Office Commercial Unit

6 W Sainte Marie Street, Perryville, MO 63775

$2,000/Mo

0.09 AC lot

Six spacious offices on the upper level
Street‑front office space with a public entrance
Bathroom plus kitchen and break area
Rear staircase leads to a private off‑street parking lot
Brick commercial building constructed in 1904

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Updated: Jun 11

Flex Space with Overhead Door

2015 South Perryville Boulevard, Perryville, MO 63775

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3,000 sqft

60x50 commercial space ready for your business, with landlord‑provided white‑box finish
Water, sewer, and electric included, plus 2 parking spaces in front and 4 in back
Two front entrances (double doors and an overhead door) and two rear entrances
Located within 1/2 mile of I‑55 for convenient access
3‑year lease with monthly payments; $1,100 deposit required

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Flexible Downtown Retail-Office Suite

519 N Main St, Perryville, MO 63775

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4,000 sqft

Commercial space offers a flexible layout with multiple offices, conference rooms, and ADA-accessible restrooms.

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Unfinished Class A Office Suite

1304-1310 Brenda Ave., Perryville, MO 63775

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Unfinished office space allows a tenant to configure the interior within a professional plaza.

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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 4 Active listings in Perryville, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Industrial Building with Office Space

1707 Doubet Rd - Rear, Farmington, MO 63640

$1,000/Mo

3,450 sqft

3,450 SF commercial building with office and warehouse space.

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Remodeled Office Space with Amenities

1427 Thomas Dr, Cape Girardeau, MO 63701

$850/Mo per office

279 sqft

Centrally located office space with modern finishes and included amenities.

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Flexible Office Unit

1469 N Kingshighway Street, Cape Girardeau, MO 63701

$1,128/Mo

Commercial space with a private bathroom and owner-approved build-to-suit options.

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Accessible Office Building

330 North St, Murphysboro, IL 62966

Contact for pricing

2,300 sqft

Flexible professional office space with a full basement, direct Highway 127 access, and off-street parking.

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Similar Spaces for Sale in Perryville, MO

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Flexible Office Building

519 Main Street, Perryville, MO 63775

$405,000

4,099 sqft

Brick office property with adaptable suites, updated interiors, multiple work areas, and on-site parking.

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Day Care with Flexible Upper Space

4 Kiefner St, Perryville, MO 63775

$350,000

4,000 sqft

Currently operating as a daycare with a flexible upper level for additional uses.

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Office Building with Attached Garage

875 PCR 500, Perryville, MO 63775

$745,000

5.16 AC lot

Flexible office property with dedicated work areas, support spaces, outbuildings, and solar panels on acreage outside city limits.

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Flex Space with Separate Office

1205 N Kingshighway St, Perryville, MO 63775

Contact for pricing

13,134 sqft

Flex property combines a large shop with a separate office building for operational and administrative functions.

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Turnkey Historic Brick Office Building

23/25/27 W Saint Joseph Street, Perryville, MO 63775

$1,150,000

Fully restored 1859 brick building with updated HVAC including central air and mini-splits, plus multiple income-producing spaces.

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Class A Professional Office Plaza

1304-1310 Brenda Ave., Perryville, MO 63775

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Professional office units in a Class A plaza with off-street parking and backlit monument signage.

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Remodeled Flex Space

805 N Main Street, Perryville, MO 63775

Contact for pricing

Updated building systems and a finished bathroom create a practical setting for office operations.

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Perryville, MO Office Spaces Lease Rates & Market Statistics

Explore 4 Office Spaces for lease in Perryville, MO on Realmo, a commercial real estate exchange covering the Perryville area. The current inventory totals 7,000 square feet of properties.

Asking lease rates for Office Spaces in Perryville start at $2,000/Mo, average $2,000/Mo, and reach $2,000/Mo at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings.