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    Perryville, MO
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    Perryville, MO Healthcare Properties for Sale

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    Turnkey Historic Brick Office Building
    Updated: Aug 22, 2025
    Turnkey Historic Brick Office Building

    23/25/27 W Saint Joseph Street, Perryville, MO 63775

    $1,150,000
    1859 brick historic commercial building, built as the first brick building on the square
    Fully replumbed, rewired, and reroofed, with updated HVAC including central air and mini‑splits
    All new windows plus tuckpointing inside and out for long‑term durability
    Currently features three office spaces, an operating salon, and three Airbnb units on the upper level
    Interior includes reception/waiting areas, multiple private offices and break rooms, and a functional layout
    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 1 Active listings in Perryville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 12 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Ambulatory Surgery Center Facility
    Ambulatory Surgery Center Facility

    3241 Percy Drive, Cape Girardeau, MO 63701

    Contact for pricing
    13,650 sqft

    For-sale ambulatory surgery center with recently upgraded HVAC and modern systems in a high-visibility medical corridor.

    View details
    Versatile Commercial Building on 1.9 Acres
    Versatile Commercial Building on 1.9 Acres

    1429 N Mount Auburn Road, Cape Girardeau, MO 63701

    $2,900,000
    13,458 sqft 1.87 AC lot

    All-brick commercial building with abundant parking and multiple use opportunities.

    View details
    St. Louis Office/Medical Space
    St. Louis Office/Medical Space

    Saint Louis, MO

    Contact for pricing
    11,764 sqft 0.70 AC lot

    Recently constructed office/medical space with easy highway access.

    View details
    DaVita Dialysis Center For Sale
    DaVita Dialysis Center For Sale

    Saint Louis, MO 63118

    $1,325,000
    5,057 sqft

    DaVita Dialysis Center in St. Louis, Missouri for sale.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 25 Historic Gem
    Highway 25 Historic Gem

    17382 State Highway 25, Dexter, MO 63841

    $179,900
    7,200 sqft 3.39 AC lot

    Historic property on 3+ acres with 7,000+ sqft and potential.

    View details
    Commercial Development Land Parcel
    Commercial Development Land Parcel

    3620 James Sanders Blvd, Paducah, KY 42001

    $600,000
    1.97 AC lot

    Nearly 2-acre parcel on James Sanders Blvd near Sam's Club and Jordan's Crossing, suited for retail or medical development.

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    Level Commercial Development Tract
    Level Commercial Development Tract

    3020 Wayne Sullivan Drive, Paducah, KY 42003

    $1,475,000
    16.50 AC lot

    Level 16.5-acre commercial site with city utilities and direct access to Wayne Sullivan Drive.

    View details
    Fulton, KY Commercial Development Site
    Fulton, KY Commercial Development Site

    Myatt Road, Fulton, KY 42041

    $1,150,000
    33.60 AC lot

    33-acre commercial development site in Fulton, KY, near I-69.

    View details

    Off-Market Properties in Perryville, MO

    Consider similar Off-Market properties in Perryville, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1508 Edgemont Blvd
    DENTAL BUILDING

    1508 Edgemont Blvd, Perryville, MO 63775-1231

    Value Estimation by Request
    6,408 sqft 1.00 AC lot
    View details
    121 Main St
    DENTAL BUILDING

    121 Main St, Perryville, MO 63775-2524

    Value Estimation by Request
    1,960 sqft
    View details
    334 Main St
    DENTAL BUILDING

    334 Main St, Perryville, MO 63775-1362

    Value Estimation by Request
    1,470 sqft
    View details
    202 Sainte Marie St
    DENTAL BUILDING

    202 Sainte Marie St, Perryville, MO 63775-2031

    Value Estimation by Request
    561 sqft
    View details
    203 Saint Joseph St
    DENTAL BUILDING

    203 Saint Joseph St, Perryville, MO 63775-1827

    Value Estimation by Request
    1,404 sqft
    View details
    908 Kingshighway St
    DENTAL BUILDING

    908 Kingshighway St, Perryville, MO 63775-2108

    Value Estimation by Request
    1,320 sqft 1.90 AC lot
    View details
    12 Jackson St
    DENTAL BUILDING

    12 Jackson St, Perryville, MO 63775-2515

    Value Estimation by Request
    3,070 sqft
    View details
    14 Jackson St
    DENTAL BUILDING

    14 Jackson St, Perryville, MO 63775-2515

    Value Estimation by Request
    1,104 sqft
    View details
    100 Jackson St
    DENTAL BUILDING

    100 Jackson St, Perryville, MO 63775-2517

    Value Estimation by Request
    2,576 sqft 0.30 AC lot
    View details
    1506 Saint Joseph St Ste, Unit 30
    DENTAL BUILDING

    1506 Saint Joseph St Ste, Perryville, MO 63775-1681

    Unit 30
    Value Estimation by Request
    9,920 sqft 1.00 AC lot
    View details
    22 St
    DENTAL BUILDING

    22 St, Perryville, MO 63775-2547

    Value Estimation by Request
    1,036 sqft 0.30 AC lot
    View details
    430 St
    HOMES (RETIRED, NURSING)

    430 St, Perryville, MO 63775-1359

    $545,000
    Estimated value
    38,876 sqft 5.30 AC lot
    View details

    Perryville, MO Healthcare Properties Market Trends and Statistics

    Explore 13 healthcare properties for sale in Perryville, MO on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $1,150,000.

    Sale prices for medical real estate in Perryville, MO start at $1,150,000, averaging $1,150,000, and reaching up to $1,150,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Spa & wellness properties 1

    Demographics Overview

    Population 17K
    Population Growth (5Y) +21.1%
    Median Household Income $65,171
    College Educated 18.7%

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cape Girardeau County

    New Delisted

    Total CRE Inventory on Market (SF)

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