Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Columbia County, FL Commercial Real Estate for Sale

    List
    Map
    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL
    115 results
    Highway Frontage Commercial Property
    $610,000
    3,168 SF

    Highway Frontage Commercial Property

    2832 SW MAIN BLVD., Lake City, FL 32025

    3,168 sq ft commercial property on 1.501 acres.

    • Prime highway frontage on Hwy 41 with convenient access to Interstate 75 offers excellent visibility and accessibility.
    • Zoned Commercial Intensive, allowing for a wide range of permitted business uses.
    • Spacious garage with three roll‑up doors provides ample room for storage.
    • 3,168 sq. ft. building (over 4,000 sq. ft. total) on a large 1.501‑acre lot provides ample space.
    • Mostly fenced property offers added security.
    Updated: Apr 2
    View details
    Lake City Office Space Available
    $198,654
    1,529 SF

    Lake City Office Space Available

    654 BAYA DR, Lake City, FL 32025

    Professional office space with multiple offices, conference room, and kitchen.

    • High‑traffic professional office space suitable for working where you live.
    • Includes 3‑4 offices, conference room, kitchen, and lobby area.
    • Central heating and air conditioning (electric).
    • Flooring includes carpet, hardwood, and tile.
    • Fenced property within city limits.
    Updated: Mar 30
    View details
    Lake City Commercial Aviation Land
    $300,000
    1.70 Acres

    Lake City Commercial Aviation Land

    Commercial land in North Florida Airpark community, easy I-75 access.

    TBD 5 & 6 POBEREZNY GLN, Lake City, FL 32025
    View details
    7.64 Acres Commercial Land
    $699,000
    7.64 Acres

    7.64 Acres Commercial Land

    Commercial zoned land in a growing area with road frontage.

    782 SW SISTERS WELCOME ROAD, Lake City, FL 32025
    View details
    Recreational Property Bordering National Forest
    $895,000
    1,322 SF

    Recreational Property Bordering National Forest

    105-acre recreational property near Lake City, Florida.

    1317 Northeast Drew Road, Lake City, FL 32055
    View details
    Lake City Commercial Aviation Lot
    $150,000
    0.50 Acres

    Lake City Commercial Aviation Lot

    Commercial lot suitable for aviation or other commercial businesses.

    LOT 6 SW POBEREZNY GLEN, Lake City, FL 32025
    View details
    Lake City Professional Office
    $295,000
    1,208 SF

    Lake City Professional Office

    Commercial office building with reception, exam rooms, and bathroom.

    1166 SW MAIN BLVD, Lake City, FL 32025
    View details
    Commercial Lot in Lake City
    $350,000
    2.13 Acres

    Commercial Lot in Lake City

    2.13-acre commercial lot suitable for various business types.

    1563 SW CENTURY GLN (LOT 2), Lake City, FL 32025
    View details
    Lake City Commercial Lot
    $150,000
    0.50 Acres

    Lake City Commercial Lot

    Commercial lot suitable for aviation or other business.

    LOT 5 SW POBEREZNY GLEN, Lake City, FL 32025
    View details
    Lake City Industrial Property
    $699,000
    15,000 SF

    Lake City Industrial Property

    15,000 SF industrial property on 1.72 acres in Lake City.

    3887 E US HIGHWAY 90, Lake City, FL 32055
    View details
    Lake City Commercial Investment Property
    $870,000
    8,800 SF

    Lake City Commercial Investment Property

    8,800 sq ft building leased to daycare center.

    258 SW Columbia Avenue, Lake City, FL 32025
    View details
    Lake City Commercial Lot
    $200,000
    2.22 Acres

    Lake City Commercial Lot

    Commercial lot in Lake City, Florida, with diverse business potential.

    1563 SW CENTURY GLN (LOT 3), Lake City, FL 32025
    View details
    Wooded Acreage Near Santa Fe River
    $450,000
    20.00 Acres

    Wooded Acreage Near Santa Fe River

    20-acre wooded property near Santa Fe River, Fort White, FL.

    290 SW RATTLESNAKE GLEN, Fort White, FL 32038
    View details
    Retail Property Near Lake City Mall
    $1,800,000
    3,607 SF

    Retail Property Near Lake City Mall

    Retail space near Walmart and Lowe's, formerly a restaurant.

    3585 NW BASCOM NORRIS, Lake City, FL 32055
    View details
    Lake City Commercial Lot Available
    $400,000
    2.04 Acres

    Lake City Commercial Lot Available

    Prime commercial lot in a rapidly developing area.

    TBD SW COMMERCE DR, Lake City, FL 32025
    View details
    Land in Lake City, FL
    $480,000
    60.00 Acres

    Land in Lake City, FL

    Commercial land available for sale in Lake City, Florida.

    358 SW SATELLITE LN, Lake City, FL 32024
    View details
    5-Acre Residential/Agricultural Land For Sale
    $105,000
    5.05 Acres

    5-Acre Residential/Agricultural Land For Sale

    5-acre tract suitable for residential, agricultural, or manufactured homes.

    330 SW BARWICK TER, Lake City, FL 32024
    View details
    Commercial Lot Near I-75
    $500,000
    3.06 Acres

    Commercial Lot Near I-75

    Commercial land in a rapidly developing area near major routes.

    TBD SW COMMERCE DR, Lake City, FL 32025
    View details
    Wooded Acreage Near Santa Fe River
    $225,000
    10.00 Acres

    Wooded Acreage Near Santa Fe River

    Gorgeous wooded 10-acre property near Santa Fe River.

    290 SW RATTLESNAKE GLEN (2), Fort White, FL 32038
    View details
    Serene 10-Acre Lot
    $325,000
    10.00 Acres

    Serene 10-Acre Lot

    10-acre lot in gated equestrian and riverfront community.

    BLUE BIRD COURT SW, Fort White, FL 32038
    View details
    Remodeled Home Office Building
    $259,900
    2,442 SF

    Remodeled Home Office Building

    Remodeled office building with live-work potential in Lake City.

    340 SE Country Club Rd, Lake City, FL 32025
    View details
    16.48 Acre Commercial Tract
    $3,000,000
    16.68 Acres

    16.48 Acre Commercial Tract

    16.48 acre commercial tract with high visibility and traffic.

    0 W W US HWY 90, Lake City, FL 32024
    View details
    Commercial Lot Near I-75
    $300,000
    2.04 Acres

    Commercial Lot Near I-75

    Commercial land in a rapidly developing area near major routes.

    TBD SW COMMERCE DR, Lake City, FL 32025
    View details
    Equestrian-Ready Land in Fort White
    $270,000
    10.05 Acres

    Equestrian-Ready Land in Fort White

    10-acre property with pole barn, stalls, and potential living quarters.

    00 SW COWPOKE COURT, Fort White, FL 32038
    View details

    Columbia County, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1822 commercial real estate for sale in Columbia County, FL, showcased through 115 active listings on our real estate platform. These investment opportunities span a total of 61,886,258 square feet of properties for sale, with an estimated market value of $35,716,644.

    Sale prices for business properties in Columbia County, FL start at $35,000, averaging $585,518, and reaching up to $4,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Commercial real estate by market

    Browse Commercial real estate for Sale Near Columbia, FL

    Popular Searches in Columbia

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!