Columbia County, FL Commercial real estate for sale

Updated: Oct 1

Multi-Tenant Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two office buildings totaling 6,054 square feet
Fully occupied by long‑term tenants
Lease renewals scheduled for 2027 and 2028
Built in 1993
Located in a Lake City commercial corridor with professional and medical office buildings nearby

View details

Updated: Aug 29

Highway-Frontage Flex Space

2832 SW MAIN BLVD., Lake City, FL 32025

$560,000

3,168 sqft 1.50 AC lot

1.501‑acre commercial site with highway frontage on Hwy 41
3,168 square feet of property size
Open lobby, four offices, and a private restroom
Garage with three roll‑up doors and upstairs storage
Mostly fenced site with millings throughout the parking area

View details

Occupied Income-Producing Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established commercial setting with existing tenants and future owner-user flexibility.

View details

Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads

Fully Occupied Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established professional-office setting with tenants in place and lease renewals scheduled through 2028.

View details

Income-Producing Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two fully occupied office buildings support ongoing tenancy and future owner-user flexibility.

View details

Single-Story Storefront Property

3585 NW BASCOM NORRIS, Lake City, FL 32055

$1,700,000

3,607 sqft 0.97 AC lot

Retail-oriented building with central HVAC, public restrooms, ceramic tile, and an existing electronics-store configuration.

View details

Fenced Single-Story Storefront

2779 SW MAIN BLVD, Lake City, FL 32025

$610,000

3,000 sqft 1.02 AC lot

Commercially zoned building with concrete flooring, central systems, and public water service.

View details

Office Building with Central Air

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Commercial office property with central air conditioning and a 1993 construction date.

View details

Mixed-Use Complex with Warehouse

743 N MARION Avenue, Lake City, FL 32055

$775,000

5,406 sqft

Concrete warehouse bays and multiple residential spaces support storage, light manufacturing, and onsite living uses.

View details

Corner Storefront Building

451 N MARION AVE, Lake City, FL 32055

$279,000

7,333 sqft 0.21 AC lot

Single-story commercial building with three rental units and an additional space currently used for storage.

View details

Express Car Wash with Absolute NNN Lease

Lake City, FL 32055

$5,120,000

10,374 sqft

Corporate-guaranteed lease includes annual rent increases and approximately 13 years remaining in the initial term.

View details

Office Building with Leased Tenants

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

3,419 sqft

The property is fully occupied, with leases scheduled to renew in 2027 and 2028.

View details

Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

2,635 sqft

Current tenancy includes leases with renewal dates in 2027 and 2028.

View details

Fully Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

2,500 sqft

Established commercial-corridor office asset with long-term occupants and lease renewals scheduled in 2027 and 2028.

View details

Historic Mixed-Use Property

398 S MARION Avenue, Lake City, FL 32025

$349,000

2,559 sqft 0.32 AC lot

Two-story commercial property with a separate carriage house, apartment, covered porch, and updated building systems.

View details

Historic Two-Story Office Building

433 S MARION AVENUE, Lake City, FL 32025

$349,900

3,968 sqft 0.65 AC lot

Flexible two-story layout with multiple rooms, common areas, and public and private restrooms.

View details

New Construction Warehouse with Office

372 Southwest Windswept Glen, Lake City, FL 32024

$1,750,000

7,500 sqft 2.01 AC lot

New 7,500 SF warehouse with office space for sale.

View details

Restored Two-Story Office Building

398 S MARION, Lake City, FL 32025

$349,000

2,079 sqft 0.32 AC lot

Historic downtown property with a separate carriage house, apartment, and updated building systems.

View details

Day Care Center Building

258 SW Columbia Ave, Lake City, FL 32025

$870,000

8,714 sqft

Currently leased to a daycare center with convenient access to I-75 and nearby major thoroughfares.

View details

Campground With Cabins And RV Sites

8587 SW ELIM CHURCH Road, Fort White, FL 32038

$1,799,000

1,800 sqft 14.84 AC lot

Multi-site campground with cabins, RV accommodations, tent camping, and an on-site convenience store.

View details

Historic Two-Story Office Building

398 S Marion Ave, Lake City, FL 32025

$355,000

2,559 sqft

Restored commercial property with updated systems, architectural character, and a separate carriage house with apartment space.

View details

Corner Mixed-Use Property

229 NE MAIN BLVD, Lake City, FL 32025

$350,000

2,465 sqft

Three adjoining parcels include a commercial-converted residence, parking, and the flexibility to support either commercial or residential use.

View details

Historic Two-Story Office Building

398 S MARION, Lake City, FL 32025

$349,000

2,079 sqft

Commercial General zoning, updated systems, and a separate carriage house support varied business configurations.

View details

Campground With Convenience Store

8587 SW ELIM CHURCH Road, Fort White, FL 32038

$1,799,000

1,800 sqft 14.84 AC lot

RV sites, cabins, primitive tent camping, and a convenience store serve a mixed-use outdoor hospitality operation.

View details

Columbia County, FL Commercial Real Estate Market Trends and Statistics

Explore 105 commercial real estate for sale in Columbia County, FL, showcased through 105 active listings on our real estate platform. These investment opportunities span a total of 263,463 square feet of properties for sale, with an estimated market value of $77,698,637.

Sale prices for business properties in Columbia County, FL start at $39,900, averaging $1,022,350, and reaching up to $5,120,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.