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    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL

    Columbia County, FL Mixed-use Properties for Sale

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    Remodeled Home Office Building
    $259,900
    2,442 SF

    Remodeled Home Office Building

    340 SE Country Club Rd, Lake City, FL 32025

    Remodeled office building with live-work potential in Lake City.

    • Newly remodeled home office building, perfect for living and running a business or leasing for income.
    • Enjoy the benefits of a new A/C, windows, paint, floors, electric throughout, and service panel.
    • Features 8 rooms and 2 bathrooms.
    • Durable metal roof.
    • Galley kitchen and convenient in‑unit washer and dryer.
    Updated: Sep 9, 2025
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    Versatile Commercial Asset with Airbnb Units
    $2,975,000
    9.06 Acres

    Versatile Commercial Asset with Airbnb Units

    1524 NW Main Boulevard, Lake City, FL 32055

    Multi-functional commercial property with retail, industrial, and residential income.

    • Over 26,000 sq ft of versatile space suitable for retail, industrial/warehouse, and mechanic shop use.
    • Strategic location near I‑10, I‑75, and the local airport, offering prime accessibility.
    • Two on‑site Airbnb units provide immediate revenue opportunities.
    • Private lake, expansive walking trails, and outdoor recreation space create a retreat‑like setting.
    • FEMA‑designated protection area ensures reliable cell coverage, beneficial for technology‑dependent operations.
    Updated: Mar 23
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    Live and Work Opportunity
    $669,000
    7,200 SF

    Live and Work Opportunity

    7,200 SF property with warehouse and residential space.

    709 SW Morning Star Gln, Fort White, FL
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    Versatile Commercial Asset with Income Streams
    $2,975,000
    25,805 SF

    Versatile Commercial Asset with Income Streams

    Multi-functional property with retail, industrial, and residential income potential.

    1524 NW Main Blvd, Lake City, FL 32055
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    Commercial Property with Highway Frontage
    $595,000
    3,168 SF

    Commercial Property with Highway Frontage

    3168 SF commercial property with garage, storage, and parking.

    2832 SW Main Blvd, Lake City, FL 32025
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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 5 Active listings in Columbia County, FL, we suggest exploring several alternatives: similar 8 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land with Rental Income
    $690,000
    5,012 SF

    Commercial Land with Rental Income

    Seven acres of commercially zoned land with rental income.

    3575 US-441, Lake City, FL 32025
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    Lake City Commercial Aviation Lot
    $100,000
    0.70 Acres

    Lake City Commercial Aviation Lot

    Commercial lot suitable for aviation or other commercial businesses.

    LOT 7 SW POBEREZNY GLEN, Lake City, FL 32025
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    Lake City Commercial Land Parcel
    $100,000
    0.70 Acres

    Lake City Commercial Land Parcel

    Commercial land parcel suitable for aviation or other businesses.

    LOT 7 SW Poberezny Glen, Lake City, FL 32025
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    Lake City Commercial Aviation Lot
    $100,000
    0.50 Acres

    Lake City Commercial Aviation Lot

    Commercial lot suitable for aviation or other business purposes.

    LOT 6 SW POBEREZNY GLEN, Lake City, FL 32025
    View details

    Explore Off-Market Properties in Columbia County, FL

    Consider similar Off-Market properties in Columbia County, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    126 Colonial Pl

    126 Colonial Pl

    STORES & APARTMENTS • 0.54 Acres
    Value Estimation by Request
    126 Colonial Pl, Lake City, FL 32025-0608
    View details
    812 Marion Ave

    812 Marion Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,756 SF
    Value Estimation by Request
    812 Marion Ave, Lake City, FL 32025-5818
    View details
    197 Waterford Ct

    197 Waterford Ct

    STORE/OFFICE (MIXED USE) • 8,522 SF
    Value Estimation
    $830,000
    197 Waterford Ct, Lake City, FL 32025-0711
    View details
    2018 Main Blvd

    2018 Main Blvd

    STORE/OFFICE (MIXED USE) • 7,974 SF
    Value Estimation
    $745,000
    2018 Main Blvd, Lake City, FL 32025-0025
    View details
    228 Marion Ave

    228 Marion Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 83,595 SF
    Value Estimation
    $9,135,000
    228 Marion Ave, Lake City, FL 32055-3917
    View details
    125 Midtown Pl

    125 Midtown Pl

    STORE/OFFICE (MIXED USE) • 4,100 SF
    Value Estimation by Request
    125 Midtown Pl, Lake City, FL 32025-0766
    View details
    207 Confederate Gln

    207 Confederate Gln

    STORES & APARTMENTS • 7,700 SF
    Value Estimation by Request
    207 Confederate Gln, Lake City, FL 32025-1639
    View details
    3827 Us-441

    3827 Us-441

    Restaurants • 1,770 SF
    Value Estimation by Request
    3827 Us-441, Lake City, FL 32055
    View details

    Columbia County, FL Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 13 mixed-use properties for sale in Columbia County, FL, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 916,615 square feet of properties for sale, with an estimated market value of $5,934,900.

    Sale prices for multi use buildings in Columbia County, FL start at $170,000, averaging $659,433, and reaching up to $2,975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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