Columbia County, FL Medical Office Space for Rent & Lease

Updated: Jun 25

Medical Office Corner Suite

229 Southwest Main Boulevard, Lake City, FL 32025

$15 SF/Yr

Two lease spaces in a Class B medical office built in 1925
Corner lot with two access points and strong frontage along Main Boulevard
Traffic count of 13,000± vehicles per day along the major corridor
Currently configured as a speech/OT therapy center with flexible medical office use
Surrounded by retail and professional services

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Updated: Nov 25, 2025

Updated Office Condo For Rent

1140 SW Bascom Norris Dr, Lake City, FL

Contact for pricing

1,801 sqft

High‑visibility location on Bascom Norris Drive with 14,500 daily vehicle traffic count.
Easy regional access, located just 1.8 miles from I‑75.
1,801± SF of updated office space with modern finishes, suitable for medical or professional use.
Features 8 private offices/patient rooms, including an executive suite with built‑ins.
Ample parking and prominent signage (monument and on‑building) for enhanced business exposure.

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Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 6 Potential Opportunities for your consideration.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Commercial Lot For Rent

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

0.66 acre commercial lot with high visibility.

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WINTER PARK Land Lease Opportunity

5589 LAKE HOWELL ROAD, Winter Park, FL 32792

$8,500/Mo

23,056 sqft $4 SF/Yr

Commercial land lease opportunity in Winter Park, Florida.

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Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft $32 SF/Yr

1.7 acre corner lot zoned for commercial, medical, residential.

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Columbia County, FL Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Columbia County, FL with 2 listings featured on our commercial real estate exchange. The current inventory includes 1,801 square feet of properties with an estimated lease value of $15 SF/Yr.

Estimated lease rates for Medical Office Space in Columbia County, FL begin at $15 SF/Yr, with an average of $15 SF/Yr and extend to $15 SF/Yr.