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    Columbia County, FL Commercial Real Estate for Lease

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    Miami, FL Jacksonville, FL Orlando, FL
    7 results
    Former Restaurant Building on US-90
    Contact for pricing

    Former Restaurant Building on US-90

    Lake City, FL 32055

    4,153 SF former restaurant on 1.38 acres available for rent.

    • High‑traffic location at a fully signalized intersection on US‑90.
    • Former restaurant building with 4,153 SF on 1.38 acres.
    • Located across from top‑performing Zaxby's, Chick‑fil‑A, and Burger King locations in Florida.
    • Proximity to a high‑performing Walmart Supercenter (top 95% nationally).
    • Close proximity to Interstate‑75.
    Updated: Nov 25, 2025
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    Retail Space on Duval Street
    $10,500/Mo

    Retail Space on Duval Street

    1780 E Duval St Ste 120, Lake City, FL 32055

    Commercial unit for rent in high-traffic Duval Street corridor.

    • Located along the Duval Street corridor.
    • Zoning allows for multiple uses.
    • Commercial unit for rent.
    • Nearby retailers include Dollar General.
    • Nearby retailers include Save‑A‑Lot.
    Updated: Jul 15, 2024
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    Retail Space in Lake City
    Contact for pricing
    2,377 SF

    Retail Space in Lake City

    Grocery-anchored neighborhood center along US Highway 90.

    255 NW Commons Loop, Lake City, FL
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    Retail Space in High Traffic Area
    $9 SF/Yr
    16,731 SF

    Retail Space in High Traffic Area

    Retail space available in a desirable, high-traffic location.

    2311 West US Highway 90, Lake City, FL
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    Former Restaurant Site For Rent
    Contact for pricing

    Former Restaurant Site For Rent

    Former restaurant site in Lake City retail corridor.

    2281 W US Hwy 90, Lake City, FL 32055
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    Commercial Lots for Ground Lease
    $1.84 SF/Yr
    1,650 SF

    Commercial Lots for Ground Lease

    Multiple lots available in new commercial development.

    FL-47, Lake City, FL 32024
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    Retail Space in Lake City
    Contact for pricing

    Retail Space in Lake City

    Retail space available in Lake City Mall on US Hwy 90.

    2469 W US Hwy 90, Lake City, FL 32055
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    Based on your search, we've compiled 134 Potential Opportunities for your consideration. Besides 7 Active listings in Columbia County, FL, we suggest exploring alternatives. Similar 127 Properties for Sales.

    Similar Spaces for Sale in Columbia County, FL

    Consider Similar Space for Sale. We found 127 Spaces matching your search parameters.

    Highway Frontage Commercial Property
    $610,000
    3,168 SF

    Highway Frontage Commercial Property

    3,168 sq ft commercial property on 1.501 acres.

    2832 SW MAIN BLVD., Lake City, FL 32025
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    Commercial Property in Lake City
    $795,000
    0.39 Acres

    Commercial Property in Lake City

    Commercial property suitable for various uses, formerly a restaurant.

    535 SW MAIN BLVD, Lake City, FL 32024
    View details
    Lake City Office Space Available
    $198,654
    1,529 SF

    Lake City Office Space Available

    Professional office space with multiple offices, conference room, and kitchen.

    654 BAYA DR, Lake City, FL 32025
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    Lake City Commercial Aviation Land
    $300,000
    1.70 Acres

    Lake City Commercial Aviation Land

    Commercial land in North Florida Airpark community, easy I-75 access.

    TBD 5 & 6 POBEREZNY GLN, Lake City, FL 32025
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    Lake City Industrial Property
    $699,000
    15,000 SF

    Lake City Industrial Property

    15,000 SF industrial property on 1.72 acres in Lake City.

    3887 E US HIGHWAY 90, Lake City, FL 32055
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    Lake City Commercial Aviation Lot
    $150,000
    0.50 Acres

    Lake City Commercial Aviation Lot

    Commercial lot suitable for aviation or other commercial businesses.

    LOT 6 SW POBEREZNY GLEN, Lake City, FL 32025
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    Recreational Property Bordering National Forest
    $895,000
    1,322 SF

    Recreational Property Bordering National Forest

    105-acre recreational property near Lake City, Florida.

    1317 Northeast Drew Road, Lake City, FL 32055
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    Lake City Professional Office
    $295,000
    1,208 SF

    Lake City Professional Office

    Commercial office building with reception, exam rooms, and bathroom.

    1166 SW MAIN BLVD, Lake City, FL 32025
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    Commercial Lot in Lake City
    $350,000
    2.13 Acres

    Commercial Lot in Lake City

    2.13-acre commercial lot suitable for various business types.

    1563 SW CENTURY GLN (LOT 2), Lake City, FL 32025
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    Lake City Commercial Lot
    $150,000
    0.50 Acres

    Lake City Commercial Lot

    Commercial lot suitable for aviation or other business.

    LOT 5 SW POBEREZNY GLEN, Lake City, FL 32025
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    Lake City Commercial Investment Property
    $870,000
    8,800 SF

    Lake City Commercial Investment Property

    8,800 sq ft building leased to daycare center.

    258 SW Columbia Avenue, Lake City, FL 32025
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    Lake City Commercial Lot
    $200,000
    2.22 Acres

    Lake City Commercial Lot

    Commercial lot in Lake City, Florida, with diverse business potential.

    1563 SW CENTURY GLN (LOT 3), Lake City, FL 32025
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    Retail Property Near Lake City Mall
    $1,800,000
    3,607 SF

    Retail Property Near Lake City Mall

    Retail space near Walmart and Lowe's, formerly a restaurant.

    3585 NW BASCOM NORRIS, Lake City, FL 32055
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    Prime Commercial Land on Highway
    $1,250,000
    3,144 SF

    Prime Commercial Land on Highway

    5.36-acre commercial land with high-visibility frontage on W US Highway.

    4967 W US HIGHWAY 90, Lake City, FL 32055
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    Lake City Commercial Lot Available
    $400,000
    2.04 Acres

    Lake City Commercial Lot Available

    Prime commercial lot in a rapidly developing area.

    TBD SW COMMERCE DR, Lake City, FL 32025
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    North Florida Ranch with Riverfront
    $4,399,000
    2,030 SF

    North Florida Ranch with Riverfront

    391-acre ranch featuring river frontage, home, barn, and workshop.

    4639 SW WILSON SPRINGS ROAD, Fort White, FL 32038
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    Commercial Lot Near I-75
    $500,000
    3.06 Acres

    Commercial Lot Near I-75

    Commercial land in a rapidly developing area near major routes.

    TBD SW COMMERCE DR, Lake City, FL 32025
    View details

    Columbia County, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Columbia County, FL with 7 listings featured on our commercial real estate exchange. The current inventory includes 22,561 square feet of properties with an estimated lease value of $51 SF/Yr.

    Estimated lease rates for Commercial real estate in Columbia County, FL begin at $9 SF/Yr, with an average of $17 SF/Yr and extend to $27 SF/Yr.
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    Browse Commercial real estate for Lease Near Columbia, FL

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