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    Columbia County, FL Office Properties & Spaces for Sale

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    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL
    10 results
    Highway Frontage Commercial Property
    $610,000
    3,168 SF

    Highway Frontage Commercial Property

    2832 SW MAIN BLVD., Lake City, FL 32025

    3,168 sq ft commercial property on 1.501 acres.

    • Prime highway frontage on Hwy 41 with convenient access to Interstate 75 offers excellent visibility and accessibility.
    • Zoned Commercial Intensive, allowing for a wide range of permitted business uses.
    • Spacious garage with three roll‑up doors provides ample room for storage.
    • 3,168 sq. ft. building (over 4,000 sq. ft. total) on a large 1.501‑acre lot provides ample space.
    • Mostly fenced property offers added security.
    Updated: Apr 2
    View details
    Lake City Office Building For Sale
    $350,000
    1,823 SF

    Lake City Office Building For Sale

    229 SW MAIN BOULEVARD, Lake City, FL 32025

    Class B office building with expansion and investment potential.

    • High‑visibility location on Main Boulevard with 13,000± daily traffic count.
    • Includes a second building suitable for commercial use, lease, or residential conversion.
    • Ample parking and two access points on a corner lot.
    • Features a radio tower, offering potential additional income or utility.
    • Secure basement for file storage and utilities.
    Updated: Dec 1, 2025
    View details
    Lake City Office Space Available
    $198,654
    1,529 SF

    Lake City Office Space Available

    Professional office space with multiple offices, conference room, and kitchen.

    654 BAYA DR, Lake City, FL 32025
    View details
    Lake City Professional Office
    $295,000
    1,208 SF

    Lake City Professional Office

    Commercial office building with reception, exam rooms, and bathroom.

    1166 SW MAIN BLVD, Lake City, FL 32025
    View details
    Remodeled Home Office Building
    $259,900
    2,442 SF

    Remodeled Home Office Building

    Remodeled office building with live-work potential in Lake City.

    340 SE Country Club Rd, Lake City, FL 32025
    View details
    Lake City Commercial Investment Opportunity
    $1,120,000
    16,050 SF

    Lake City Commercial Investment Opportunity

    Fully leased commercial property with long-term tenants and immediate income.

    260 S Marion Avenue, Lake City, FL 32025
    View details
    Commercial Building in Downtown Lake
    $249,000

    Commercial Building in Downtown Lake

    Commercial building in Lake City suitable for store or office.

    508 N Marion Ave, Lake City, FL 32055
    View details
    New Construction Warehouse with Office
    $1,850,000
    7,500 SF

    New Construction Warehouse with Office

    New 7,500 SF warehouse with office space for sale.

    372 Southwest Windswept Glen, Lake City, FL 32024
    View details
    Live and Work Opportunity
    $669,000
    7,200 SF

    Live and Work Opportunity

    7,200 SF property with warehouse and residential space.

    709 SW Morning Star Gln, Fort White, FL
    View details
    Commercial Property with Highway Frontage
    $595,000
    3,168 SF

    Commercial Property with Highway Frontage

    3168 SF commercial property with garage, storage, and parking.

    2832 SW Main Blvd, Lake City, FL 32025
    View details
    Based on your search, we've compiled 384 Potential Opportunities for your consideration. Besides 10 Active listings in Columbia County, FL, we suggest exploring several alternatives: similar 370 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Lake City Commercial Aviation Lot
    $150,000
    0.50 Acres

    Lake City Commercial Aviation Lot

    Commercial lot suitable for aviation or other businesses.

    LOT 5 SW Poberezny Glen, Lake City, FL 32025
    View details
    7.64 Acres Commercial Land
    $699,000
    7.64 Acres

    7.64 Acres Commercial Land

    Commercial zoned land in a growing area with road frontage.

    782 SW SISTERS WELCOME ROAD, Lake City, FL 32025
    View details
    Prime Commercial Land Opportunity
    $365,000

    Prime Commercial Land Opportunity

    2.41 acres of commercial land with high development potential.

    702 South Marion Avenue, Lake City, FL 32025
    View details
    Commercial Lot Near I-75
    $250,000
    1.02 Acres

    Commercial Lot Near I-75

    Commercial land in a rapidly developing area near major routes.

    637 SW COMMERCE DR, Lake City, FL 32025
    View details

    Explore Off-Market Properties in Columbia County, FL

    Consider similar Off-Market properties in Columbia County, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2230 Baya Dr

    2230 Baya Dr

    OFFICE (GENERAL) • 7,413 SF
    Value Estimation by Request
    2230 Baya Dr, Lake City, FL 32025-8006
    View details
    4330 American Ln

    4330 American Ln

    OFFICE (GENERAL) • 8,409 SF
    Value Estimation
    $1,485,000
    4330 American Ln, Lake City, FL 32055
    View details
    176 Lk Jeffery Rd

    176 Lk Jeffery Rd

    OFFICE (GENERAL) • 2,005 SF
    Value Estimation by Request
    176 Lk Jeffery Rd, Lake City, FL 32055-3869
    View details
    677 Bascom Norris Dr

    677 Bascom Norris Dr

    OFFICE (GENERAL) • 4,770 SF
    Value Estimation
    $550,000
    677 Bascom Norris Dr, Lake City, FL 32025-1598
    View details
    4355 American Ln

    4355 American Ln

    MEDICAL BUILDING • 2,607 SF
    Value Estimation by Request
    4355 American Ln, Lake City, FL 32055-4828
    View details
    1111 Main Blvd

    1111 Main Blvd

    MEDICAL BUILDING • 3,474 SF
    Value Estimation by Request
    1111 Main Blvd, Lake City, FL 32025-5767
    View details
    1779 Barnett Way

    1779 Barnett Way

    MEDICAL BUILDING • 3,140 SF
    Value Estimation by Request
    1779 Barnett Way, Lake City, FL 32025-6957
    View details
    2303 Baya Dr

    2303 Baya Dr

    OFFICE (GENERAL) • 1,012 SF
    Value Estimation by Request
    2303 Baya Dr, Lake City, FL 32025-4908
    View details
    161 Lk Jeffery Rd

    161 Lk Jeffery Rd

    OFFICE (GENERAL) • 3,080 SF
    Value Estimation by Request
    161 Lk Jeffery Rd, Lake City, FL 32055-3870
    View details
    650 Main Blvd

    650 Main Blvd

    OFFICE (GENERAL) • 2,296 SF
    Value Estimation by Request
    650 Main Blvd, Lake City, FL 32025-5783
    View details
    618 Florida Gtwy Dr

    618 Florida Gtwy Dr

    OFFICE (GENERAL) • 2,488 SF
    Value Estimation
    $530,000
    618 Florida Gtwy Dr, Lake City, FL 32024-3853
    View details
    1152 Business Pt Dr

    1152 Business Pt Dr

    OFFICE (GENERAL) • 45,751 SF
    Value Estimation
    $2,540,000
    1152 Business Pt Dr, Lake City, FL 32025-3184
    View details
    678 Baya Dr

    678 Baya Dr

    OFFICE (GENERAL) • 1,305 SF
    Value Estimation by Request
    678 Baya Dr, Lake City, FL 32025-6038
    View details
    763 Main Blvd

    763 Main Blvd

    MEDICAL BUILDING • 8,612 SF
    Value Estimation
    $875,000
    763 Main Blvd, Lake City, FL 32025-5791
    View details

    Columbia County, FL Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 380 office properties & spaces for sale in Columbia County, FL, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 20,624,918 square feet of properties for sale, with an estimated market value of $120,473,554.

    Sale prices for office spaces in Columbia County, FL start at $50,000, averaging $424,202, and reaching up to $9,290,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Columbia, FL

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