Lake City, FL Commercial real estate for sale

Updated: Oct 1

Multi-Tenant Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two office buildings totaling 6,054 square feet
Fully occupied by long‑term tenants
Lease renewals scheduled for 2027 and 2028
Built in 1993
Located in a Lake City commercial corridor with professional and medical office buildings nearby

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Updated: Aug 29

Highway-Frontage Flex Space

2832 SW MAIN BLVD., Lake City, FL 32025

$560,000

3,168 sqft 1.50 AC lot

1.501‑acre commercial site with highway frontage on Hwy 41
3,168 square feet of property size
Open lobby, four offices, and a private restroom
Garage with three roll‑up doors and upstairs storage
Mostly fenced site with millings throughout the parking area

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Occupied Income-Producing Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established commercial setting with existing tenants and future owner-user flexibility.

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Fully Occupied Office Building

885 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

6,054 sqft

Established professional-office setting with tenants in place and lease renewals scheduled through 2028.

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Income-Producing Office Buildings

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Two fully occupied office buildings support ongoing tenancy and future owner-user flexibility.

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Single-Story Storefront Property

3585 NW BASCOM NORRIS, Lake City, FL 32055

$1,700,000

3,607 sqft 0.97 AC lot

Retail-oriented building with central HVAC, public restrooms, ceramic tile, and an existing electronics-store configuration.

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Fenced Single-Story Storefront

2779 SW MAIN BLVD, Lake City, FL 32025

$610,000

3,000 sqft 1.02 AC lot

Commercially zoned building with concrete flooring, central systems, and public water service.

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Office Building with Central Air

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$1,400,000

6,054 sqft

Commercial office property with central air conditioning and a 1993 construction date.

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Mixed-Use Complex with Warehouse

743 N MARION Avenue, Lake City, FL 32055

$775,000

5,406 sqft

Concrete warehouse bays and multiple residential spaces support storage, light manufacturing, and onsite living uses.

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Corner Storefront Building

451 N MARION AVE, Lake City, FL 32055

$279,000

7,333 sqft 0.21 AC lot

Single-story commercial building with three rental units and an additional space currently used for storage.

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Express Car Wash with Absolute NNN Lease

Lake City, FL 32055

$5,120,000

10,374 sqft

Corporate-guaranteed lease includes annual rent increases and approximately 13 years remaining in the initial term.

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Office Building with Leased Tenants

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

3,419 sqft

The property is fully occupied, with leases scheduled to renew in 2027 and 2028.

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Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$750,000

2,635 sqft

Current tenancy includes leases with renewal dates in 2027 and 2028.

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Fully Occupied Office Building

853 SW SISTERS WELCOME ROAD, Lake City, FL 32025

$650,000

2,500 sqft

Established commercial-corridor office asset with long-term occupants and lease renewals scheduled in 2027 and 2028.

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Historic Mixed-Use Property

398 S MARION Avenue, Lake City, FL 32025

$349,000

2,559 sqft 0.32 AC lot

Two-story commercial property with a separate carriage house, apartment, covered porch, and updated building systems.

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Historic Two-Story Office Building

433 S MARION AVENUE, Lake City, FL 32025

$349,900

3,968 sqft 0.65 AC lot

Flexible two-story layout with multiple rooms, common areas, and public and private restrooms.

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New Construction Warehouse with Office

372 Southwest Windswept Glen, Lake City, FL 32024

$1,750,000

7,500 sqft 2.01 AC lot

New 7,500 SF warehouse with office space for sale.

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Restored Two-Story Office Building

398 S MARION, Lake City, FL 32025

$349,000

2,079 sqft 0.32 AC lot

Historic downtown property with a separate carriage house, apartment, and updated building systems.

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Day Care Center Building

258 SW Columbia Ave, Lake City, FL 32025

$870,000

8,714 sqft

Currently leased to a daycare center with convenient access to I-75 and nearby major thoroughfares.

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Corner Mixed-Use Property

229 NE MAIN BLVD, Lake City, FL 32025

$350,000

2,465 sqft

Three adjoining parcels include a commercial-converted residence, parking, and the flexibility to support either commercial or residential use.

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Historic Two-Story Office Building

398 S Marion Ave, Lake City, FL 32025

$355,000

2,559 sqft

Restored commercial property with updated systems, architectural character, and a separate carriage house with apartment space.

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Commercial Land With Highway Frontage

US Hwy 41, Lake City, FL 32025

$799,000

1.70 AC lot

A Lake City parcel fronts two state routes at an interchange.

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Historic Two-Story Office Building

398 S MARION, Lake City, FL 32025

$349,000

2,079 sqft

Commercial General zoning, updated systems, and a separate carriage house support varied business configurations.

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Day Care Center Building

258 SW Columbia Avenue, Lake City, FL 32025

$870,000

8,800 sqft 1.01 AC lot

Leased commercial facility with on-site parking and public water and sewer service.

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Lake City, FL Commercial Real Estate Market Trends and Statistics

Explore 88 commercial real estate for sale in Lake City, FL, showcased through 88 active listings on our real estate platform. These investment opportunities span a total of 250,939 square feet of properties for sale, with an estimated market value of $57,726,738.

Sale prices for business properties in Lake City, FL start at $39,900, averaging $946,339, and reaching up to $5,120,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Lake City, FL CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
Fernandina Beach - 32034	$139.5K
Lake City - 32024	$903.8K

Neighborhood

Average Price

Fernandina Beach - 32034

$139.5K

Lake City - 32024

$903.8K