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    Perryville, MO
    Spa & Wellness

    Perryville, MO Spa & Wellness Properties for Sale

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    Oak Ridge, MO Daisy, MO Sedgewickville, MO Jackson, MO Millersville, MO Hermann, MO Frohna, MO Marble Hill, MO
    Remodeled Flex Space
    Updated: Aug 31
    Remodeled Flex Space

    805 N Main Street, Perryville, MO 63775

    $235,000
    0.19 AC lot
    2023 remodel with updated plumbing, HVAC, and electrical wiring
    Full‑view storefront and 10' x 10' garage door
    30' x 47' paved parking area
    0.189‑acre parcel in Perryville, MO
    Finished bathroom with walk‑in shower and ceramic tile flooring
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    Turnkey Historic Brick Office Building
    Updated: Oct 13, 2025
    Turnkey Historic Brick Office Building

    23/25/27 W Saint Joseph Street, Perryville, MO 63775

    $1,150,000
    1859 brick historic commercial building, built as the first brick building on the square
    Fully replumbed, rewired, and reroofed, with updated HVAC including central air and mini‑splits
    All new windows plus tuckpointing inside and out for long‑term durability
    Currently features three office spaces, an operating salon, and three Airbnb units on the upper level
    Interior includes reception/waiting areas, multiple private offices and break rooms, and a functional layout
    View details
    See what stands out in Cape Girardeau County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 2 Active listings in Perryville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Freestanding VA Outpatient Clinic
    Freestanding VA Outpatient Clinic

    608 Rollie Moore Dr, Harrisburg, IL 62946

    $2,400,000
    11,900 sqft 1.50 AC lot

    Fully leased outpatient clinic built-to-suit in 2012, anchored by the U.S. Department of Veterans Affairs.

    View details
    Mixed-Use Commercial Property
    Mixed-Use Commercial Property

    109 West Poplar Street, Harrisburg, IL 62946

    $550,000
    27,859 sqft

    Flexible commercial layout with private rooms, salon infrastructure, and a separate garage building.

    View details
    Salon Building with Full Basement
    Salon Building with Full Basement

    1501 Garfield Avenue, Granite City, IL 62040

    $129,000
    0.20 AC lot

    Commercially zoned salon property with flexible interior space, updated mechanical systems, and supplemental basement area.

    View details
    Single-Story Office Building
    Single-Story Office Building

    3307 Wabash Avenue, Granite City, IL 62040

    Contact for pricing

    Single-story office building with common waiting area, separate side entrances, and 27 parking spaces plus an additional lot.

    View details

    Perryville, MO Spa & Wellness Properties Market Trends and Statistics

    Explore 2 spa & wellness properties for sale in Perryville, MO on our real estate platform.

    Sale prices for spa & wellness properties in Perryville, MO start at $235,000, averaging $692,500, and reaching up to $1,150,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Spa & wellness properties 2

    Demographics Overview

    Population 17K
    Population Growth (5Y) +21.1%
    Median Household Income $65,171
    College Educated 18.7%

    High-Yield Neighborhoods for Investment

    Identify Perryville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63775 $1.2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cape Girardeau County

    New Delisted

    Total CRE Inventory on Market (SF)

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