Seneca, SC Retail Properties & Spaces for Sale

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$1,800,000

1.01 Acres

Seneca Retail/Warehouse Opportunity

518 W N 1st Street, Seneca, SC 29678

All brick/concrete building with existing tenants and expansion potential.

High‑traffic location in a growing area of Seneca, SC.
All brick/concrete building construction.
Existing tenants occupy approximately 8000 sqft, providing immediate income.
Over 7000 sqft available for new tenant or owner‑occupancy.
Warehouse‑style construction with 16‑foot ceilings.

Updated: Jan 7

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Turn-Key Restaurant Franchise Opportunity

$1,900,000

0.78 Acres

Turn-Key Restaurant Franchise Opportunity

1053 By Pass 123 Bypass, Seneca, SC 29678

Turn-key national franchise restaurant with real estate for sale.

Turn‑key, cash‑flowing Moe's Southwest Grill franchise with associated real estate.
Built in 2020, substantially below replacement cost.
Located on the busiest highway in Seneca, SC with approximately 35,000 daily vehicles.
Limited fast casual restaurant competition in the direct market.
#1 for catering in the Upstate region (Greenville‑Spartanburg‑Anderson).

Updated: Oct 10, 2025

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$1,399,999

12,000 SF

Seneca Retail Building For Sale

12,000 SF building with conversion potential in Seneca, SC.

12020 North Radio Station Road, Seneca, SC 29678

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$125,000

Seneca Automotive Service Property

Automotive service property near downtown Seneca with four bays.

919 E S 6th Street, Seneca, SC 29678

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$3,500,000

4.33 Acres

Prime Commercial Acreage For Sale

4.3 acres in Seneca, SC, ideal for retail or hospitality.

1018 E. North 1st Street, Seneca, SC 29678

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$1,399,999

12,000 SF

Seneca Retail Building For Sale

12,000 SF building with conversion potential in Seneca, SC.

12020 N Radio Station Rd, Seneca, SC 29678

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$900,000

Automotive Shop Near Lake Keowee

10-bay automotive shop, redevelopment potential for fast food.

445 By Pass 123, Seneca, SC 29678

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$219,000

Established Hibachi Restaurant for Sale

Turnkey Hibachi restaurant with existing lease and equipment included.

1510 Blue Ridge Boulevard, Seneca, SC 29672

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$350,000

Land Near Clemson University

Land available near Clemson University, close to lakes.

Union Station Dr, Seneca, SC 29678

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Based on your search, we've compiled 361 Potential Opportunities for your consideration. Besides 9 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 344 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

$490,000

0.06 Acres

Renovated Commercial Space on Main

Prime commercial space ideal for retail, office, or restaurant.

212 E Main Street, Walhalla, SC 29691

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$1,300,000

6,130 SF

Historic Retail Buildings on Main

Renovated retail spaces with historic charm and modern amenities.

214-218 E Main St, Walhalla, SC

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$375,000

686 SF

Retail Opportunity with Road Frontage

Flat site suitable for retail, restaurant, or automotive businesses.

821 W Main St, Central, SC

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$289,000

686 SF

Road Frontage Commercial Land

Commercial land with road frontage, suitable for various businesses.

821 West Main, Central, SC 29630

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$699,000

Unrestricted Commercial Land Near Highway

1.8 acres of unrestricted commercial land with high traffic count.

1.8 Acres Rochester Highway, Seneca, SC 29672

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$699,000

1.80 Acres

Commercial Land Near Highway 123

Unrestricted 1.8-acre commercial land near major retailers and highways.

1.8 Acres Rochester Highway, Seneca, SC 29672

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$275,000

2.50 Acres

Commercial Land in Seneca, SC

2.5-acre commercial lot in Seneca, ready for development.

13000 S Radio Station Road, Seneca, SC 29678

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$395,000

0.99 Acres

Commercial Lot Near Wells Highway

0.99-acre commercial lot with high visibility and easy access.

RETAIL STORES (PERSONAL SERVICES) • 16,236 SF

Value Estimation

$1,380,000

991 By Pass 123, Seneca, SC 29678-4758

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997 By Pass 123

WHOLESALE OUTLET, DISCOUNT STORE • 7,070 SF

Value Estimation

$715,000

997 By Pass 123, Seneca, SC 29678-4760

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13020 Clemson Blvd

DRIVE-THRU RESTAURANT, FAST FOOD • 2,309 SF

Explore 353 retail properties & spaces for sale in Seneca, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 5,918,062 square feet of properties for sale, with an estimated market value of $61,450,000.

Sale prices for stores in Seneca, SC start at $50,000, averaging $722,941, and reaching up to $3,315,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Seneca, SC Retail Properties & Spaces for Sale

Seneca Retail/Warehouse Opportunity

All brick/concrete building with existing tenants and expansion potential.

Turn-Key Restaurant Franchise Opportunity

Turn-key national franchise restaurant with real estate for sale.

Seneca Retail Building For Sale

Seneca Automotive Service Property

Prime Commercial Acreage For Sale

Seneca Retail Building For Sale

Automotive Shop Near Lake Keowee

Established Hibachi Restaurant for Sale

Land Near Clemson University

Explore Opportunities in Nearby Cities

Renovated Commercial Space on Main

Historic Retail Buildings on Main

Retail Opportunity with Road Frontage

Road Frontage Commercial Land

Potential Development Sites for Consideration

Unrestricted Commercial Land Near Highway

Commercial Land Near Highway 123

Commercial Land in Seneca, SC

Commercial Lot Near Wells Highway

Explore Off-Market Properties in Seneca, SC

403 Main St

717 Wn 1st St

126 Ram Cat Aly

975 By Pass 123

Seneca, SC 29678

202 Walnut St

711 Wn 1st St

991 By Pass 123

997 By Pass 123

13020 Clemson Blvd

123 En 1st St

211 En 1st St

696 By Pass 123

408 En 1st St

103 Townville St

Seneca, SC Retail Properties & Spaces Investment Opportunities Market Analysis

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