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    San Diego, CA Office Units for Lease

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    Los Angeles, CA San Francisco, CA Sacramento, CA
    544 results
    Prominent Office Space Available
    $2 SF/Yr
    9,483 SF

    Prominent Office Space Available

    15015 Avenue of Science, San Diego, CA

    High-visibility office space with abundant natural light and parking.

    • High visibility corner location with monument signage opportunity
    • Unusually large amount of glass line providing spectacular natural light
    • Total building size is approximately 84,789 s.f.
    • Mix of prime offices and large bullpen areas
    • Entire building features 11’ interior ceiling height
    Updated: Nov 24, 2025
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    Hillcrest Office/Retail Space Available
    $30 SF/Yr
    2,649 SF

    Hillcrest Office/Retail Space Available

    3590 5th Ave, San Diego, CA 92103

    Flexible 2,649 SF space in Hillcrest with private parking.

    • High visibility location on 5th Ave, near Balboa Park.
    • 2,649 SF of flexible office/retail space.
    • Secured rear double‑door access from private parking lot for deliveries.
    • Low NNN fees ($0.58/SF).
    • Private parking lot.
    Updated: Mar 23
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    Remodeled Office Space in San Diego
    $2.00 SF/Yr
    26,457 SF

    Remodeled Office Space in San Diego

    Recently remodeled office space with modern updates and exceptional convenience.

    4010 Morena Blvd., San Diego, CA 92117
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    Kearny Mesa HQ and Warehouse
    $1.90 SF/Yr
    33,862 SF

    Kearny Mesa HQ and Warehouse

    Corporate HQ with warehouse space in Kearny Mesa.

    7520 Mission Valley Road, San Diego, CA 92108
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    Downtown San Diego Office Space
    $1.50 SF/Yr
    9,040 SF

    Downtown San Diego Office Space

    Prime corner location with private entrance and outdoor patio.

    415 Broadway, San Diego, CA
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    Creative Office Space For Lease
    Contact for pricing
    592 SF

    Creative Office Space For Lease

    Creative office space with secure parking and high-speed internet.

    2251 San Diego Ave, San Diego, CA 92110
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    Mission Valley Office Space Available
    Contact for pricing
    2,146 SF

    Mission Valley Office Space Available

    Office space for lease in the heart of Mission Valley.

    1450 Frazee Rd, San Diego, CA 92108
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    Kearny Mesa Office/Flex Space
    $1,298 /Mo
    32,144 SF

    Kearny Mesa Office/Flex Space

    Office and flex space with freeway access in Kearny Mesa.

    7854-7924 Ronson Road, San Diego, CA 92111
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    San Diego Office Space Available
    Contact for pricing
    1,808 SF

    San Diego Office Space Available

    Office space for lease in San Diego, California.

    5030 Camino de La Siesta, San Diego, CA 92108
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    Redeveloped Class A Lab Space
    Contact for pricing
    15,809 SF

    Redeveloped Class A Lab Space

    Available for lease: redeveloped Class A lab space.

    11388 Sorrento Valley Rd, San Diego, CA 92121
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    Furnished Office Sublease Available
    $2 SF/Yr
    5,160 SF

    Furnished Office Sublease Available

    Furnished office space available for sublease until August 2025.

    10805 Rancho Bernardo Rd, San Diego, CA
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    Class A Office Space Available
    Contact for pricing
    2,790 SF

    Class A Office Space Available

    Class A office space with flexible layouts and convenient location.

    6256 Greenwich Dr, San Diego, CA 92122
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    Class A Office Space Available
    Contact for pricing
    4,713 SF

    Class A Office Space Available

    Quality office space with flexible layouts and convenient location.

    6363 Greenwich Dr, San Diego, CA 92122
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    Mira Mesa Office Suites Available
    $1.80 SF/Yr
    19,189 SF

    Mira Mesa Office Suites Available

    Office suites available in Miramar with immediate I-15 access.

    9672 Via Excelencia, San Diego, CA 92126
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    La Jolla Class A Office
    Contact for pricing
    2,430 SF

    La Jolla Class A Office

    Class A office space for lease in La Jolla.

    7777 Fay Ave, La Jolla, CA 92037
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    Modern Office Space Available
    $4 SF/Yr
    6,886 SF

    Modern Office Space Available

    Plug-n-Play office space with modern buildout and shared patio.

    12626 High Bluff Drive, San Diego, CA 92130
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    Creative Space with Ocean Views
    Contact for pricing
    9,090 SF

    Creative Space with Ocean Views

    Tastefully designed creative space with ocean views available for sublease.

    3344 North Torrey Pines Court, Suite 110, La Jolla, CA 92037
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    Industrial Flex Suites For Rent
    Contact for pricing
    2,200 SF

    Industrial Flex Suites For Rent

    Industrial/Flex suites available for lease, climate-controlled with private offices.

    9823 Pacific Heights Blvd, San Diego, CA 92121
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    San Diego Office Space Available
    Contact for pricing
    1,149 SF

    San Diego Office Space Available

    Office spaces for lease in San Diego, ranging from 1,043-7,134 SF.

    591 Camino de La Reina, San Diego, CA 92108
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    Office Space with Mountain Views
    $2 SF/Yr
    2,806 SF

    Office Space with Mountain Views

    Office space with high visibility and easy freeway access.

    11590 W Bernardo Court, San Diego, CA
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    Creative Office Space Sublease
    Contact for pricing
    9,561 SF

    Creative Office Space Sublease

    High-end creative office space in central Mission Valley available for sublease.

    350 Camino De La Reina, Suite 140, San Diego, CA 92108
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    Class A Office Space Available
    $3 SF/Yr
    2,156 SF

    Class A Office Space Available

    Prestigious office suite with highway access and park views.

    13478 SABRE SPRINGS PKY, San Diego, CA
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    Waples Research Centre Lab Space
    Contact for pricing
    9,300 SF

    Waples Research Centre Lab Space

    Lab space available for lease in San Diego, California.

    9535 Waples St, San Diego, CA 92121
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    Rancho Bernardo Plug & Play Office
    Contact for pricing
    3,801 SF

    Rancho Bernardo Plug & Play Office

    Plug & Play office suite in Rancho Bernardo available for sublease.

    11545 W. Bernardo Ct., Suite 305, San Diego, CA 92127
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    San Diego, CA Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in San Diego, CA with 544 listings featured on our commercial real estate exchange. The current inventory includes 23,634,131,400 square feet of properties with an estimated lease value of $485 /Mo.

    Estimated lease rates for Office Units in San Diego, CA begin at $0.99 SF/Yr, with an average of $9 SF/Yr and extend to $106 SF/Yr.
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    Popular Searches in San Diego, CA

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    Most Searched ZIP Codes in San Diego, CA

    • 92121
    • 92101
    • 92123
    • 92108
    • 92037
    • 92127
    • 92131
    • 92111
    • 92103
    • 92122
    • 92126

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