San Diego, CA Office Units for Lease

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Coronado, CA National City, CA La Mesa, CA Lemon Grove, CA Chula Vista, CA Bonita, CA Spring Valley, CA Vista, CA

557 properties

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Updated: Jun 19

Cornerstone Plaza Office Suites

6160-6170 Cornerstone Ct E, San Diego, CA 92121

$1,025/Mo

29,530 sqft

Refreshed office suites in San Diego’s Sorrento Mesa submarket
Flexible suite sizes
Abundant natural light in the office space
Thoughtfully reimagined outdoor spaces
Convenient access to major freeways

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Updated: Jul 20

Creative Office Suite with Character

3047 University Ave, San Diego, CA 92104

$1,545/Mo

1,281 sqft

1,281‑square‑foot creative office suite
Open floor plan supports workstations, collaboration, meetings, or showroom use
Exposed brick accent walls and high ceilings
Large windows with updated lighting
Private office and built‑in cabinetry

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Hillcrest Office/Retail Space Available

3590 5th Ave, San Diego, CA 92103

$8,800/Mo

2,649 sqft 0.14 AC lot

Flexible 2,649 SF space in Hillcrest, convenient location.

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Move-In Ready Office Suite with Cat 5

1919 Grand #2C-2D, San Diego, CA 92109

$2,400/Mo

Second-floor office suite with open work area, two private offices, kitchenette, and Cat 5 cabling throughout.

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Remodeled Medical Office Suite

1919 Grand #2K, San Diego, CA 92109

$1,200/Mo

Move-in ready second-floor suite with an open work area, rear space, secure restrooms, and elevator access.

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Remodeled Office Suite

1919 Grand #2A-2D, San Diego, CA 92109

$4,800/Mo

Second-floor workspace with private offices, reception, conference space, kitchenette, and Cat 5 cabling throughout.

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Two-Story Flex Space

6262 Ferris Square, San Diego, CA 92121

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6,904 sqft

HVAC-equipped commercial space with loading access and dedicated parking in Sorrento Mesa.

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Fully Furnished Spec Creative Suite

401 W A St, San Diego, CA 92101

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2,649 sqft

Fully furnished spec creative suite with creative finishes.

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Medical Office with Exam Rooms

7625 Mesa College Dr, San Diego, CA 92111

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2,868 sqft

Configured for clinical operations with private offices, shared support areas, and available FF&E.

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Office Units with Bay Views

550 W C St, San Diego, CA 92101

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4,137 sqft

Fully equipped conference room, gym, showers, lockers, and on-site security support daily operations.

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Flex R&D Space

9765 Clairemont Mesa Blvd, San Diego, CA 92124

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9,030 sqft

Adaptable configuration supports office use alongside ground-floor manufacturing or warehouse functions.

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Flex Office with Production Areas

15025 Innovation Dr, San Diego, CA 92128

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11,437 sqft

Flexible workspace includes offices, multiple conference and huddle rooms, break areas, and production space.

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Corner Flex Office with Parking

9235 Activity Rd., San Diego, CA 92126

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7,754 sqft

Office and flexible industrial space recently updated with improved signage, common areas, landscaping, and outdoor seating.

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Divisible Office Suite with Views

16745 W Bernardo Dr, San Diego, CA 92127

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2,637 sqft

Divisible office space with showers and locker facilities, vaulted lobby, and signage opportunities.

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Office Units with Flexible Floorplates

15435 Avenue of Science, San Diego, CA 92128

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3,300 sqft

Configured for office, R&D, biotech, life science, or lab operations within a master-planned corporate setting.

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Upgraded Lab Office Suites

12250 El Camino Real, San Diego, CA 92130

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4,900 sqft

Upgraded office suites with robust MEP systems, offering multiple lab suite sizes within a large building.

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Flex Lab and Office Suite

11095 Flintkote Ave, San Diego, CA 92121

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3,094 sqft

Balanced lab and office buildout includes benches, fume hood, and multiple private offices.

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First-Floor Office Units

9682 Via Excelencia, San Diego, CA 92126

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4,198 sqft

Office availability includes ample parking and connections to I-15 via Miramar Road.

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Life Science Office Unit

9310 Athena Cir, La Jolla, CA 92037

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6,025 sqft

Research-oriented workspace within UC San Diego’s Science Research Park, near academic, healthcare, life science, and technology organizations.

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Corner Office Suite

3655 Nobel Dr, San Diego, CA 92122

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4,028 sqft

Corner suite with glass double-door entry from the elevator lobby and multiple private offices, conference and meeting rooms.

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Flex Office and Laboratory Suite

5627 Oberlin Dr, San Diego, CA 92121

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10,712 sqft

Flex suite with 6 lab benches, 2 fume hoods, and office buildout including workstations and conference space.

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Turnkey Office Suite

5465 Morehouse Dr, San Diego, CA 92121

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3,040 sqft

Office suite with six private offices, reception, conference room, and break, copy, and storage areas.

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Upgraded Lab-Ready Office Suites

12250 El Camino Real, San Diego, CA 92130

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11,000 sqft

Office suites sized from 4,500 to 11,800 SF within an upgraded building designed for laboratory MEP needs.

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Remodeled Office Space in San Diego

4010 Morena Blvd., San Diego, CA 92117

$22.20 SF/Yr

26,457 sqft

Recently remodeled office space with excellent accessibility and high visibility.

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San Diego, CA Office Units Lease Rates & Market Statistics

Explore 557 Office Units for lease in San Diego, CA on Realmo, a commercial real estate exchange covering the San Diego area. The current inventory totals 4,909,875 square feet of properties — an average of ~8,800 SF per listing.

Office Units lease rates in San Diego range from $14.47 SF/Yr at the entry level to $39.86 SF/Yr at the top of the market, averaging $23.78 SF/Yr. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $23.78 SF/Yr is in line with the California state average.

San Diego accounts for 64% of the 869 office units currently available across San Diego County, where nearby markets include Carlsbad and Oceanside. Office Units make up 66% of the 843 Office Spaces currently for lease in San Diego, with asking rates averaging $23.78 SF/Yr — 14% above the citywide Office Spaces average of $20.83 SF/Yr. Also worth a look for tenants weighing alternatives: Office buildings (207 listings) and Medical Office Space (56 listings) elsewhere in the San Diego market.

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