Add Listing
    San Diego, CA
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    San Diego, CA Office Buildings for Lease

    Notify Me
    List
    Map
    Coronado, CA National City, CA Chula Vista, CA
    74 results
    Prominent Office Space For Rent
    $2 SF/Yr
    13,739 SF
    Prominent Office Space For Rent

    10875 Rancho Bernardo Rd, San Diego, CA 92127

    High-visibility office space with modern facade and landscaping.
    • Prominent corner location with outstanding visibility and signage opportunities.
    • Modern glass and concrete façade for a high‑image corporate presence.
    • Close to 4S Ranch’s newest dining, housing, and retail amenities.
    • Beautifully landscaped campus with a central courtyard and water feature.
    • Local, responsive ownership and management (Brehm Properties) with portfolio scalability.
    Updated: Apr 29
    View details
    Premier Del Mar Office Space
    Contact for pricing
    2,346 SF
    Premier Del Mar Office Space

    12555 High Bluff Dr, San Diego, CA 92130

    Class A office with upgraded interiors and tranquil courtyard.
    • Premier Class A office building in prestigious Del Mar area.
    • Walkability to amenities including new retail at One Paseo.
    • Move‑in ready spec suites with private balconies and abundant natural light.
    • Tranquil, lushly landscaped courtyard with seating areas for collaboration and breaks.
    • Excellent access to I‑5 and Hwy 56.
    Updated: Apr 15
    View details
    Kearny Mesa Office Space Available
    Contact for pricing
    3,025 SF
    Kearny Mesa Office Space Available

    Three-building office campus in Kearny Mesa with recent renovations.

    3890 Murphy Canyon Rd, San Diego, CA 92123

    View details
    Rancho Bernardo Class A Office
    Contact for pricing
    8,441 SF
    Rancho Bernardo Class A Office

    Class A office/corporate campus in Rancho Bernardo for lease.

    15333 Avenue of Science, San Diego, CA 92128

    View details
    Prominent Corner Office Building
    Contact for pricing
    9,483 SF
    Prominent Corner Office Building

    Office building with high visibility and natural light.

    15015 Avenue of Science, San Diego, CA 92128

    View details
    La Jolla Office Space Available
    Contact for pricing
    2,027 SF
    La Jolla Office Space Available

    Office space for lease in the Merrill Lynch Building.

    7825 Fay Ave, La Jolla, CA 92037

    View details
    Office Space at The Oberlin
    Contact for pricing
    30,000 SF
    Office Space at The Oberlin

    Office space available for lease in San Diego, California.

    5893 Oberlin Dr, San Diego, CA 92121

    View details
    Proposed Class A Office Building
    $3 SF/Yr
    2,749 SF
    Proposed Class A Office Building

    Proposed 4-story Class A office building with I-15 access.

    16870 W Bernardo Dr, San Diego, CA

    View details
    Modernized Office Space in Liberty
    Contact for pricing
    12,627 SF
    Modernized Office Space in Liberty

    Class A office space in revitalized Liberty Station community.

    2305 Historic Decatur Road, San Diego, CA 92106

    View details
    Office Space Available For Sublease
    Contact for pricing
    38,244 SF
    Office Space Available For Sublease

    Office building II sublease opportunity in San Diego, California.

    5887 Copley Dr, San Diego, CA 92111

    View details
    San Diego Office Space Available
    Contact for pricing
    28,078 SF
    San Diego Office Space Available

    Office space for lease in San Diego, California.

    16701-16725 W Bernardo Dr, San Diego, CA 92127

    View details
    Convenient Office Space Near I-15
    Contact for pricing
    Convenient Office Space Near I-15

    Office space with easy access to I-15 and amenities.

    3655 Ruffin Rd., San Diego, CA 92123

    View details
    Renovated Class A Office Building
    $34 SF/Yr
    11,000 SF
    Renovated Class A Office Building

    Class A office building in Little Italy with recent renovations.

    909 W Laurel St, San Diego, CA 92101

    View details
    Office Building in San Diego
    $5 SF/Yr
    234,000 SF
    Office Building in San Diego

    Office building with 234,000 square feet available for rent.

    2100 Kettner Blvd, San Diego, CA 92101

    View details
    Downtown San Diego Office Space
    Contact for pricing
    14,040 SF
    Downtown San Diego Office Space

    Office space available for lease in downtown San Diego.

    1133 Columbia Street, San Diego, CA 92101

    View details
    San Diego Office Space Available
    Contact for pricing
    27,505 SF
    San Diego Office Space Available

    Office building with 27,505 square feet available for rent.

    2550 5th Ave., San Diego, CA 92103

    View details
    Class A Office Space Available
    $2 SF/Yr
    5,386 SF
    Class A Office Space Available

    Two-story, 29,639 SF office space with freeway access.

    8889 Rio San Diego Dr, San Diego, CA

    View details
    Office Space in San Diego
    Contact for pricing
    129,919 SF
    Office Space in San Diego

    Available office space totaling 129,919 square feet in San Diego.

    12220 Scripps Summit Dr., San Diego, CA 92131

    View details
    Two-Story Office Building For Rent
    $2 SF/Yr
    2,640 SF
    Two-Story Office Building For Rent

    5,320 SF office building near Little Italy and Balboa Park.

    3593 5th Ave, San Diego, CA

    View details
    Kearny Mesa Office Space Available
    $2 SF/Yr
    16,582 SF
    Kearny Mesa Office Space Available

    Office building in Kearny Mesa with freeway access and visibility.

    4715 Viewridge Ave, San Diego, CA

    View details
    Three-Story Office Building For Rent
    $2 SF/Yr
    2,039 SF
    Three-Story Office Building For Rent

    78,388 SF office building with freeway access and amenities.

    8989 Rio San Diego Dr, San Diego, CA

    View details
    Class A La Jolla Office
    Contact for pricing
    2,896 SF
    Class A La Jolla Office

    Four-story Class A office building in coastal La Jolla.

    San Diego, CA

    View details
    Class A La Jolla Property
    $3 SF/Yr
    23,729 SF
    Class A La Jolla Property

    Premier coastal submarket location with on-site parking and carwash.

    San Diego, CA

    View details
    Class A Sorrento Office Campus
    Contact for pricing
    55,659 SF
    Class A Sorrento Office Campus

    Two-building campus with ocean views and extensive amenities.

    5010 Wateridge Vista Drive, San Diego, CA

    View details

    San Diego, CA Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in San Diego, CA with 74 listings featured on our commercial real estate exchange. The current inventory includes 432,726 square feet of properties with an estimated lease value of $154 SF/Yr.

    Estimated lease rates for Office buildings in San Diego, CA begin at $1.75 SF/Yr, with an average of $9 SF/Yr and extend to $38 SF/Yr.
    List
    Map

    Popular Searches in San Diego, CA

    Popular Categories

    Most Searched ZIP Codes in San Diego, CA

    • 92101
    • 92130
    • 92121
    • 92123
    • 92131
    • 92106
    • 92122
    • 92127
    • 92037
    • 92108
    • 92128

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!