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    South Portland, ME Office Properties & Spaces for Sale

    7 results
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    Mixed-Use Property in South Portland
    $560,000
    4,370 SF

    Mixed-Use Property in South Portland

    854 Broadway, South Portland, ME 04106

    Mixed-use property with office spaces and apartment in South Portland.

    • Highly visible location on a popular commuter street.
    • Mixed‑use property with office spaces and a residential apartment.
    • Immaculate 1‑bedroom apartment with cherry cabinets and granite counters.
    • Multiple office spaces feature hardwood floors and natural sunlight.
    • Detached 1‑car garage leased year‑round.
    Updated: Oct 30, 2025
    View details
    Mixed-Use Property in South Portland
    $560,000
    0.23 Acres

    Mixed-Use Property in South Portland

    854 Broadway, South Portland, ME 04106

    Mixed-use property with office spaces and apartment in South Portland.

    • Mixed‑use property in a highly visible location on a popular commuter street.
    • Immaculate 1‑bedroom apartment on the 3rd floor featuring 2 egresses, cherry cabinets, and granite counters.
    • Two first‑floor office spaces with separate entries and beautiful hardwood floors.
    • Four individual offices on the second floor.
    • Detached 1‑car garage leased year‑round.
    Updated: Oct 30, 2025
    View details
    South Portland Medical Investment Opportunity
    $4,327,286
    7,424 SF

    South Portland Medical Investment Opportunity

    Long-term NNN investment with a strong healthcare tenant.

    254 Western Ave, South Portland, ME
    View details
    Professional Condo Near Maine Mall
    $925,000
    4,530 SF

    Professional Condo Near Maine Mall

    Office space ideal for medical, dental, wellness, or clinical services.

    25B Long Creek Drive, South Portland, ME 4106
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    Medical Outpatient Portfolio For Sale
    $1,154,664
    4,952 SF

    Medical Outpatient Portfolio For Sale

    Two-property medical portfolio fully leased to Straine Dental Management.

    25 Long Creek Drive, South Portland, ME 4106
    View details
    Office Space Near Maine Mall
    $3,800,000
    2,495 SF

    Office Space Near Maine Mall

    2,495 SF mixed-use/office space near Maine Mall.

    244 Western Ave, South Portland, ME 4106
    View details
    Medical Office Space For Sale
    $3,800,000
    19,188 SF

    Medical Office Space For Sale

    19,188 SF medical office space on 2.61 acres.

    244 Western Ave, South Portland, ME 4106
    View details
    Based on your search, we've compiled 167 Potential Opportunities for your consideration. Besides 7 Active listings in South Portland, ME, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 152 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Professional Office Building For Sale
    $399,000
    1,608 SF

    Professional Office Building For Sale

    Well-maintained 1,608± SF office building with signage opportunity.

    796 Forest Ave, Portland, ME
    View details
    Portland Flex Space For Sale
    $750,000
    2,764 SF

    Portland Flex Space For Sale

    Flex space available for sale in Portland, Maine.

    429 Deering Avenue, Portland, ME 4103
    View details
    Class A Office Building For Sale
    $4,595,000
    1,000 SF

    Class A Office Building For Sale

    Class A office building in a rapidly developing commercial corridor.

    202 Larrabee Road, Westbrook, ME 4092
    View details
    Westbrook Industrial Distribution/Headquarters Opportunity
    $8,750,000
    61,120 SF

    Westbrook Industrial Distribution/Headquarters Opportunity

    61,000+ SF turnkey industrial building near Portland Jetport.

    41 Eisenhower Dr, Westbrook, ME 4092
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Windham Commercial Land on Route
    $1,800,000
    6,000 SF

    Windham Commercial Land on Route

    17+ acre commercial land with high visibility and accessibility.

    30, 32, 34 Roosevelt Trail, Windham, ME 04062
    View details
    3.2 Acres on Route 1
    $895,000
    139,392.00 Acres

    3.2 Acres on Route 1

    3.2 acres on Route 1 in Biddeford, Maine.

    532 Elm Street, US Route 1, Biddeford, ME 04005
    View details
    Windham Commercial Land Opportunity
    $975,000
    11.95 Acres

    Windham Commercial Land Opportunity

    Rare 11.95-acre commercial land for sale in Windham, Maine.

    0 Roosevelt Trail, Windham, ME 04062
    View details
    Commercial Land in Limington, ME
    $400,000
    2,595 SF

    Commercial Land in Limington, ME

    Commercial property with potential for multiple offices and ample storage.

    192 Ossipee Trail, Limington, ME 04049
    View details

    Explore Off-Market Properties in South Portland, ME

    Consider similar Off-Market properties in South Portland, ME. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    884 Broadway

    884 Broadway

    OFFICE BUILDING • 3,862 SF
    Value Estimation
    $500,000
    884 Broadway, South Portland, ME 04106-4371
    View details
    72 Ocean St Ste, Unit 105

    72 Ocean St Ste, Unit 105

    CONDOMINIUM OFFICES • 1,620 SF
    Value Estimation by Request
    72 Ocean St Ste, South Portland, ME 04106-2840
    View details
    160 Western Ave

    160 Western Ave

    OFFICE BUILDING • 11,025 SF
    Value Estimation
    $2,950,000
    160 Western Ave, South Portland, ME 04106-2414
    View details
    210 Western Ave, Unit C

    210 Western Ave, Unit C

    CONDOMINIUM OFFICES • 3,300 SF
    Value Estimation
    $525,000
    210 Western Ave, South Portland, ME 04106-2424
    View details
    1006 Broadway

    1006 Broadway

    OFFICE BUILDING • 1,280 SF
    Value Estimation by Request
    1006 Broadway, South Portland, ME 04106-4205
    View details
    100 Main St

    100 Main St

    OFFICE BUILDING • 2,400 SF
    Value Estimation
    $2,000,000
    100 Main St, South Portland, ME 04106-2620
    View details
    345 Cottage Rd

    345 Cottage Rd

    OFFICE BUILDING • 1,612 SF
    Value Estimation by Request
    345 Cottage Rd, South Portland, ME 04106-3919
    View details
    138 Ocean St

    138 Ocean St

    OFFICE BUILDING • 3,407 SF
    Value Estimation
    $690,000
    138 Ocean St, South Portland, ME 04106-3652
    View details
    429 Preble St, Unit 1

    429 Preble St, Unit 1

    CONDOMINIUM OFFICES • 400 SF
    Value Estimation by Request
    429 Preble St, South Portland, ME 04106-3034
    View details
    373 Broadway

    373 Broadway

    OFFICE BUILDING • 3,786 SF
    Value Estimation
    $845,000
    373 Broadway, South Portland, ME 04106-2952
    View details
    75 Dartmouth St

    75 Dartmouth St

    OFFICE BUILDING • 5,086 SF
    Value Estimation
    $700,000
    75 Dartmouth St, South Portland, ME 04106-6211
    View details
    210 Western Ave, Unit A2

    210 Western Ave, Unit A2

    CONDOMINIUM OFFICES • 1,650 SF
    Value Estimation by Request
    210 Western Ave, South Portland, ME 04106-2424
    View details
    14 Gary L Maietta Pkwy

    14 Gary L Maietta Pkwy

    OFFICE BUILDING • 1,820 SF
    Value Estimation by Request
    14 Gary L Maietta Pkwy, South Portland, ME 04106-7816
    View details
    39 Wallace Ave

    39 Wallace Ave

    OFFICE BUILDING • 18,740 SF
    Value Estimation
    $2,155,000
    39 Wallace Ave, South Portland, ME 04106-6143
    View details
    241 Running Hl Rd

    241 Running Hl Rd

    OFFICE BUILDING • 6,257 SF
    Value Estimation
    $1,840,000
    241 Running Hl Rd, South Portland, ME 04106-3220
    View details
    854 Broadway

    854 Broadway

    OFFICE BUILDING • 2,451 SF
    Value Estimation by Request
    854 Broadway, South Portland, ME 04106-2712
    View details
    324 Cummings Rd

    324 Cummings Rd

    OFFICE BUILDING • 15,504 SF
    Value Estimation
    $2,600,000
    324 Cummings Rd, South Portland, ME 04106-3262
    View details

    South Portland, ME Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 159 office properties & spaces for sale in South Portland, ME, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 2,828,785 square feet of properties for sale, with an estimated market value of $35,395,000.

    Sale prices for office spaces in South Portland, ME start at $250,000, averaging $448,037, and reaching up to $2,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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