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Oconee County, SC Office Properties & Spaces for Lease

9 results
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Office Space in Seneca, SC
$2,500 /Mo
26,136 SF

Office Space in Seneca, SC

865 Old Clemson Hwy, Seneca, SC 29678

Commercial office space available for lease in Seneca, South Carolina.

  • Central heating for those chilly nights.
  • Electric heating available as well.
  • Central air to keep you cool and comfortable.
  • Enjoy electric cooling options.
  • Built in 1997.
Last Update: Nov 11
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Prime Location Office/Retail Space
$31 SF/Yr

Prime Location Office/Retail Space

1217 Stamp Creek Rd, Salem, SC 29676

New office/retail space near Lake Keowee, customizable to tenant needs.

  • Prime location near mid‑lake Keowee and upscale subdivisions.
  • Suitable for food and beverage operation due to grease trap and drainfield.
  • Versatile shell building allows tenant to tailor space to their needs.
  • New construction (built in 2025).
  • Suitable for office or retail businesses (lawyer, financial planner, small retail).
Last Update: Aug 28
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Move-in Ready Office Space
$2,200 /Mo
15,246 SF

Move-in Ready Office Space

Well-maintained office space in established professional park, ready for occupancy.
111 N Earle St, Walhalla, SC 29691
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Seneca Office Space For Lease
$1,500 /Mo
26,136 SF

Seneca Office Space For Lease

Two-level office building suitable for various businesses, near Clemson.
865 Old Clemson Hwy, Seneca, SC 29678
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Professional Office Space in Seneca
$2,200 /Mo
30,056 SF

Professional Office Space in Seneca

Office space near downtown Seneca with utilities included.
815 Robin Dr Unit, Seneca, SC 29678
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Office Space Near Clemson
$4,000 /Mo
26,136 SF

Office Space Near Clemson

Two-level office building suitable for various businesses, near Clemson.
865 Old Clemson Hwy, Seneca, SC 29678
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Seneca Office Space For Rent
$15 SF/Yr
2,900 SF

Seneca Office Space For Rent

Office space in the heart of Seneca, ample parking.
735 N Townville St, Seneca, SC 29678
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West Union Office Space Available
$10 SF/Yr
4,800 SF

West Union Office Space Available

Office space available for rent in West Union, SC.
153 Scenic Plaza Dr, West Union, SC 29696
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Seneca Office/Retail Space Available
$15 SF/Yr
4,800 SF

Seneca Office/Retail Space Available

Office and retail spaces for lease in Seneca, South Carolina.
12019 North Radio Station Rd, Seneca, SC 29678
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Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 9 Active listings in Oconee County, SC, we suggest exploring alternatives. Similar 16 Properties for Sales.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land on US Highway
$72,000
63,162 SF

Commercial Land on US Highway

1.45 acre commercial land for ground lease in Seneca, SC.
994 Us 123 Hwy, Seneca, SC 29678
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Explore Similar Spaces for Sale in Oconee County, SC

Consider Similar Space for Sale. We found 16 Spaces in Nearby Locations matching your search parameters.

Commercial Building on Highway 28
$579,000
0.77 Acres

Commercial Building on Highway 28

Meticulously maintained commercial building with high visibility and ample parking.
3691 Blue Ridge Blvd, Walhalla, SC 29691
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Move-in Ready Office Space
$349,900
0.35 Acres

Move-in Ready Office Space

Well-maintained office space in established park, ideal for professionals.
111 N Earle St, Walhalla, SC 29691
View details
Westminster Commercial Space For Sale
$145,000
1,148 SF

Westminster Commercial Space For Sale

Versatile commercial space in high-traffic Westminster location.
111 Retreat St, Westminster, SC 29693
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Commercial Property on Radio Station Rd
$250,000
0.63 Acres

Commercial Property on Radio Station Rd

Commercial property with road frontage, suitable for business location.
11081 N Radio Station Rd, Seneca, SC 29678
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Seneca Office Building For Sale
$565,000

Seneca Office Building For Sale

Office building in prime location suitable for professional organizations.
402 Cane Creek Landing Rd, Seneca, SC 29672
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Medical Office NNN Investment
$2,283,233
6,227 SF

Medical Office NNN Investment

Single tenant medical office building with long-term lease.
10110 Clemson Blvd, Seneca, SC 29672
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Seneca Office Space For Sale
$599,000
2,400 SF

Seneca Office Space For Sale

Office space conveniently located off Bypass 123 in Seneca, SC.
631 By Pass 123, Seneca, SC 29678
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Walhalla Main Street Multi-Tenant
$1,300,000
6,130 SF

Walhalla Main Street Multi-Tenant

Prime Retail Investment, Downtown Walhalla
212 Main St, Walhalla, SC 29691
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Seneca Medical Office Building
$2,283,233
6,227 SF

Seneca Medical Office Building

High-yield, single-tenant medical office
10110 Clemson Blvd, Seneca, SC 29672
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Walhalla Office Space - Main Street
Contact for pricing

Walhalla Office Space - Main Street

Affordable Office Suite in Downtown Walhalla
112 Main St, Walhalla, SC 29691
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Downtown Seneca Office Space
Contact for pricing
0.11 Acres

Downtown Seneca Office Space

Prime Seneca location, flexible office suites.
108 North 1St St, Seneca, SC 29678
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Seneca Office Building For Sale
$499,950
0.15 Acres

Seneca Office Building For Sale

Modern Office Space, Turn-Key Ready
8 Accountants Cir, Seneca, SC 29678
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Walhalla Office Space - Main Street
Contact for pricing

Walhalla Office Space - Main Street

Prime Office Space, Downtown Walhalla. Affordable and Convenient.
112 Main St, Walhalla, SC 29691
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Seneca Office Building - High Traffic Area
$250,000
0.78 Acres

Seneca Office Building - High Traffic Area

Prime Seneca location, high visibility, multiple uses.
108 Keowee School Rd, Seneca, SC 29672
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Walhalla Office Building For Sale
$185,000
0.08 Acres

Walhalla Office Building For Sale

Prime Office Space, Ample Parking
107 Earle St, Walhalla, SC 29691
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Oconee County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Oconee County, SC with 25 listings featured on our commercial real estate exchange. The current inventory includes 16,605,525,041 square feet of properties with an estimated lease value of $9,963 /Mo.

Estimated lease rates for Office Properties & Spaces in Oconee County, SC begin at $1.15 SF/Yr, with an average of $1,107 /Mo and extend to $4,000 /Mo.
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