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Natick, MA Office Spaces for Lease

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37 properties
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Third-Floor Office Suite
Updated: Jul 8
Third-Floor Office Suite

3-34 Main St, Natick, MA 01760

$19.25 SF/Yr
3,705 sqft
Third‑floor office suite in an elevator building
Mix of private offices and open collaborative workspace
Kitchenette and two bathrooms within the suite
Located in Natick Center at 3‑34 Main St
Walkable access to shops, restaurants, and public transportation
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Second-Floor Office Suite
Updated: Aug 23
Second-Floor Office Suite

209 West Central St Unit 216, Natick, MA 01760

$20 SF/Yr
315 sqft
Sublease term available through 1/31/2027
Second‑floor office configuration
Reception area plus private office
Furniture negotiable
209 West Central St, Unit 216, Natick, MA 01760
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Renovated Office Suite with Elevator
Renovated Office Suite with Elevator

210-4 Mechanic St, Natick, MA 01760

$1,500/Mo
950 sqft

Fully renovated office space with ADA-compliant access, private reception, abundant natural light, and elevator service.

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Second-Floor Office Suite
Second-Floor Office Suite

216-209 W Central St, Natick, MA 01760

$20 SF/Yr
315 sqft

Compact workspace with reception and a private office for a small business or individual.

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Lower-Level Office Unit
Lower-Level Office Unit

B2-31 S Main St, Natick, MA 01760

$900/Mo
625 sqft

625-square-foot commercial suite with shared restrooms, tenant-paid utilities, and immediate availability for professional use.

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Furnished Flex Lab & Office
Furnished Flex Lab & Office

5 Strathmore Rd, Natick, MA 01760

Contact for pricing
10,000 sqft

Fully furnished flex layout with office and R&D/testing/assembly space, plus loading dock and ample on-site parking.

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Lab/Office Sublease Space
Lab/Office Sublease Space

1 Strathmore Road, Natick, MA 01760

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10,201 sqft

Sublease-ready lab/office space with convenient highway access and proximity to the airport for corporate and R&D teams.

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Natick Center Commercial Space Available
Natick Center Commercial Space Available

31 S Main Street, Unit B2, Natick, MA 01760

$900/Mo
625 sqft

Lower level commercial space in Natick Center for rent.

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Coworking Office and Lab Space
Coworking Office and Lab Space

21 Strathmore Rd, Natick, MA 01760

$2,000/Mo per office

Move-in ready coworking suite with shared conference rooms and kitchens, plus a loading dock and ample parking.

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Commercial Office Unit with Natural Light
Commercial Office Unit with Natural Light

48 Eliot St, Natick, MA 01760

$22 SF/Yr

Flexible commercial layout supports professional, studio, or business use.

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Furnished Office Suite
Furnished Office Suite

204a-4 Mechanic St, Natick, MA 01760

$1,000/Mo

Furnished office suite in a modern elevator-served building with ample on-site parking.

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Retail, Medical, Office Space Available
Retail, Medical, Office Space Available

69 East Central Street, Natick, MA 01760

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8,920 sqft

First floor retail, medical, and office space for lease.

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Natick Office Space for Rent
Natick Office Space for Rent

5 Commonwealth Road, Natick, MA 01760

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2,090 sqft

2,090 SF office space available in Natick, MA.

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Retail Space with High Ceilings
Retail Space with High Ceilings

1-23 Main St, Natick, MA 01760

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1,600 sqft

Retail and office spaces in a signature downtown building with 12' to 14' ceilings.

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Renovated Office Building with Elevator
Renovated Office Building with Elevator

4 Mechanic St 200, Natick, MA 01760

$1,500/Mo
0.99 AC lot

Modern office suites with reception area, walkable to downtown.

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Renovated Three-Story Office Building
Renovated Three-Story Office Building

220 N Main St, Natick, MA 01760

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3,400 sqft

Renovated office building offers modern upgrades, on-site showers, and ample surface parking across three stories.

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Renovated Office Suites with High Ceilings
Renovated Office Suites with High Ceilings

1-23 Main Street & 2 Summer Street, Natick, MA 01760

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Victorian-era office building with renovated suites, soaring ceilings, and modern systems in downtown Natick’s landmark setting.

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Flexible Office Suite Layouts
Flexible Office Suite Layouts

209 W Central St, Natick, MA 01760

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Available office suites offer private offices, open work areas, conference rooms, and reception spaces with multiple floor plan options.

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Single-Tenant Office Unit
Single-Tenant Office Unit

150 E Central St, Natick, MA 01760

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2,946 sqft

Dedicated office accommodation with a single-tenant configuration.

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Furnished Flex Office/R&D Space
Furnished Flex Office/R&D Space

5 Strathmore Rd, Natick, MA 01760

Contact for pricing
10,000 sqft

Fully furnished flex space with a loading dock and a 50/50 split between office and R&D/testing/assembly.

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Two Standalone Office Buildings For Rent
Two Standalone Office Buildings For Rent

180 W Central Street, Natick, MA 01760

$6,000/Mo

Two office buildings on a corner lot available for lease.

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Renovated Office Building with Elevator
Renovated Office Building with Elevator

4 Mechanic St #200, Natick, MA 01760

$1,500/Mo

Modern office suites with reception area, walkable to transportation.

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Office Space with Street Exposure
Office Space with Street Exposure

780 Worcester St, Natick, MA 01760

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3,276 sqft

Office space available for rent along Worcester Street in Natick, offering visibility to local and commuter traffic.

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Corner Office Space
Corner Office Space

92 Park Ave, Natick, MA 01760

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3,300 sqft 0.34 AC lot

Office units on a prominent corner lot in a high-traffic Route 9 corridor with multi-use potential.

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Natick, MA Office Spaces Lease Rates & Market Statistics

Browse 37 Office Spaces for lease in Natick, MA on Realmo, a commercial real estate marketplace serving the Natick area. The current inventory totals 188,443 square feet of properties — an average of ~5,100 SF per listing.

Office Spaces lease rates in Natick range from $17.28 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $19.25 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $19.25 SF/Yr, the local average runs 29% below Massachusetts's state average of $27.22 SF/Yr.

Natick accounts for 3% of the 1,476 office spaces currently available across Middlesex County, where nearby markets include Cambridge and Waltham. By space type, the market includes 26 office units, 8 office buildings and 6 medical office space listings.

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