Mixed-Use
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Natick, MA Mixed-use Properties for Sale

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Downtown Natick Retail Opportunity
Updated: Nov 21, 2025
Downtown Natick Retail Opportunity

21 Summer Street, Natick, MA 01760

Contact for pricing
28,422 sqft
Prime location in Downtown Natick, across from The Center for Arts in Natick (TCAN), attracting approximately 30,000 patrons annually.
Up to 4,800 square feet of street‑level retail space in a newly developed mixed‑use building (Year Built: 2024).
Well‑suited for a restaurant with a ventilation shaft for a 16' hood and a partial open‑air concept dining room.**
Located steps from Natick Common, with high visibility and accessibility to dining, shopping, and entertainment.
Convenient transportation via the Natick Center MBTA Commuter Rail station, providing access to Boston.
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Natick Center Redevelopment Opportunity
Updated: Dec 12, 2024
Natick Center Redevelopment Opportunity

49 Summer, Natick, MA 01760

$1,049,000
99,999 sqft
Prime location in the heart of thriving Natick Center.
Two‑family house PLUS detached commercial/retail building.
Tremendous potential for transformation/redevelopment.
Situated steps from recently constructed developments.
Strong demand offers significant upside potential.
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Mixed-Use Property with Four Buildings
Mixed-Use Property with Four Buildings

21 Eliot Street, Natick, MA 01760

$7,200,000

Multiple existing structures combine office and retail space across a flexible suburban commercial setting.

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See what stands out in Middlesex County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Downtown Natick Mixed-Use Building
Downtown Natick Mixed-Use Building

45 East Central Street, Natick, MA 01760

Contact for pricing
89,500 sqft

Street-level retail/restaurant space in a newly developed mixed-use building.

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Based on your search, we've compiled 50 Potential Opportunities for your consideration. Besides 4 Active listings in Natick, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 38 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Income Property
Mixed-Use Income Property

8-12 Exchange Ct, Waltham, MA 02451

$2,399,999
0.22 AC lot

Residential rentals and a warehouse tenancy create a diversified operating mix.

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Mixed-Use Building Near Moody Street
Mixed-Use Building Near Moody Street

55-57 Crescent Street, Waltham, MA 02453

$2,399,000
4,585 sqft

Mixed-use property with residential, rooming house, and salon spaces.

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Mixed-Use Property Near Commuter Rail
Mixed-Use Property Near Commuter Rail

12 & 14 Waverly Street, Framingham, MA 01702

$1,480,000
3,487 sqft

Mixed-use property with auto repair potential near commuter rail.

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Framingham Mixed-Use Retail Property
Framingham Mixed-Use Retail Property

665 Cochituate Rd, Framingham, MA 01701

Contact for pricing
10,240 sqft

10,240 SqFt mixed-use retail and office property for sale.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Auburndale Village VC2-Zoned Land
Auburndale Village VC2-Zoned Land

283 Melrose Street, Newton, MA 02466

$8,999,000

Rare opportunity for housing and mixed-use development in Newton.

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Approved Condo Development Site
Approved Condo Development Site

231-245 Grove St, Boston, MA 02132

$3,695,000
1 sqft 0.31 AC lot

Approved 33-unit luxury condo development site in West Roxbury.

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General Business Commercial Land
General Business Commercial Land

W Main St lot: 108, Upton, MA 01568

$500,000
5.45 AC lot

General Business zoning supports commercial and service-oriented uses, subject to Town approvals.

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Sutton Land Development Opportunity
Sutton Land Development Opportunity

30 & 34 Pleasant Valley Road, Sutton, MA 01590

Contact for pricing
15.08 AC lot

15.08 acre land site with development potential.

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Off-Market Properties in Natick, MA

Consider similar Off-Market properties in Natick, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

54 Eliot St
OFFICE/RESIDENTIAL (MIXED USE)

54 Eliot St, Natick, MA 01760

$1,285,000
Estimated value
4,301 sqft 0.19 AC lot
View details
49 Summer St
OFFICE/RESIDENTIAL (MIXED USE)

49 Summer St, Natick, MA 01760-4521

$640,000
Estimated value
4,230 sqft 0.19 AC lot
View details
30 Main St
OFFICE/RESIDENTIAL (MIXED USE)

30 Main St, Natick, MA 01760-3422

$415,000
Estimated value
5,112 sqft 0.24 AC lot
View details
25 Central St
OFFICE/RESIDENTIAL (MIXED USE)

25 Central St, Natick, MA 01760-4550

$625,000
Estimated value
2,766 sqft 0.23 AC lot
View details
303 Main St
OFFICE/RESIDENTIAL (MIXED USE)

303 Main St, Natick, MA 01760-1118

$440,000
Estimated value
1,838 sqft 0.76 AC lot
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987 Worcester St
OFFICE/RESIDENTIAL (MIXED USE)

987 Worcester St, Natick, MA 01760-2032

$280,000
Estimated value
2,170 sqft 0.26 AC lot
View details
17 Cochituate St
OFFICE/RESIDENTIAL (MIXED USE)

17 Cochituate St, Natick, MA 01760-3486

$500,000
Estimated value
2,730 sqft 0.13 AC lot
View details
254 Main St
OFFICE/RESIDENTIAL (MIXED USE)

254 Main St, Natick, MA 01760-1152

$465,000
Estimated value
2,464 sqft 0.11 AC lot
View details
991 Worcester St
OFFICE/RESIDENTIAL (MIXED USE)

991 Worcester St, Natick, MA 01760-2032

$325,000
Estimated value
4,158 sqft 0.38 AC lot
View details
295 Bacon St
OFFICE/RESIDENTIAL (MIXED USE)

295 Bacon St, Natick, MA 01760-2088

$760,000
Estimated value
3,388 sqft 0.45 AC lot
View details
161 Pond St
OFFICE/RESIDENTIAL (MIXED USE)

161 Pond St, Natick, MA 01760-4320

$505,000
Estimated value
2,409 sqft 0.33 AC lot
View details
59 Summer St
OFFICE/RESIDENTIAL (MIXED USE)

59 Summer St, Natick, MA 01760-4521

$675,000
Estimated value
4,557 sqft 0.13 AC lot
View details
29 Central St
OFFICE/RESIDENTIAL (MIXED USE)

29 Central St, Natick, MA 01760-4501

$505,000
Estimated value
2,527 sqft 0.22 AC lot
View details
4 Wellesley Rd
OFFICE/RESIDENTIAL (MIXED USE)

4 Wellesley Rd, Natick, MA 01760-1428

$260,000
Estimated value
2,578 sqft 0.14 AC lot
View details
31 Main St
OFFICE/RESIDENTIAL (MIXED USE)

31 Main St, Natick, MA 01760-4960

$6,940,000
Estimated value
45,676 sqft 0.57 AC lot
View details
1 Main St
OFFICE/RESIDENTIAL (MIXED USE)

1 Main St, Natick, MA 01760-3403

$1,065,000
Estimated value
7,404 sqft 0.09 AC lot
View details
13 Central St
OFFICE/RESIDENTIAL (MIXED USE)

13 Central St, Natick, MA 01760-4560

$3,950,000
Estimated value
26,780 sqft 0.32 AC lot
View details
39 Main St
OFFICE/RESIDENTIAL (MIXED USE)

39 Main St, Natick, MA 01760-4948

$685,000
Estimated value
4,514 sqft 0.16 AC lot
View details
6 Dewey St
OFFICE/RESIDENTIAL (MIXED USE)

6 Dewey St, Natick, MA 01760-4602

$545,000
Estimated value
3,012 sqft 0.25 AC lot
View details
41 Central St
OFFICE/RESIDENTIAL (MIXED USE)

41 Central St, Natick, MA 01760-4503

$740,000
Estimated value
4,368 sqft 0.17 AC lot
View details

Natick, MA Mixed-Use Properties Market Trends and Statistics

Explore 42 mixed-use properties for sale in Natick, MA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 217,921 square feet of properties for sale, with an estimated market value of $8,249,000.

Sale prices for multi use buildings in Natick, MA start at $1,049,000, averaging $4,124,500, and reaching up to $7,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Live-work space 1

Demographics Overview

Population 37K
Population Growth (5Y) +2.1%
Median Household Income $134,644

High-Yield Neighborhoods for Investment

Identify Natick submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
01760 $3M

Taxes & Financing

Tax Rate (average for all types) 1.23%
Property Tax per SF $11.62 per SF
Tax Rate vs County Average 0.54 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Middlesex County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Middlesex County

Retail

Property Size Breakdown

The majority of commercial real estate listings in Natick fall within the 100,000+ square foot range.

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