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    Natick, MA Mixed-use Properties for Sale

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    Wellesley, MA Framingham, MA Sherborn, MA
    Natick Center Redevelopment Opportunity
    $1,199,000
    0.19 Acres
    Natick Center Redevelopment Opportunity

    49 Summer, Natick, MA 1760

    Two-family house plus detached commercial/retail building in Natick Center.
    • Prime location in the heart of thriving Natick Center.
    • Two‑family house PLUS detached commercial/retail building.
    • Tremendous potential for transformation/redevelopment.
    • Situated steps from recently constructed developments.
    • Strong demand offers significant upside potential.
    Updated: Nov 27, 2025
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    Downtown Natick Retail Opportunity
    Contact for pricing
    28,422 SF
    Downtown Natick Retail Opportunity

    21 Summer Street, Natick, MA 1760

    Retail space in a newly developed mixed-use building.
    • Prime location in Downtown Natick, across from The Center for Arts in Natick (TCAN), attracting approximately 30,000 patrons annually.
    • Up to 4,800 square feet of street‑level retail space in a newly developed mixed‑use building (Year Built: 2024).
    • Well‑suited for a restaurant with a ventilation shaft for a 16' hood and a partial open‑air concept dining room.
    • Located steps from Natick Common, with high visibility and accessibility to dining, shopping, and entertainment.
    • Convenient transportation via the Natick Center MBTA Commuter Rail station, providing access to Boston.
    Updated: Nov 21, 2025
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    Downtown Natick Mixed-Use Building
    Contact for pricing
    89,500 SF
    Downtown Natick Mixed-Use Building

    Street-level retail/restaurant space in a newly developed mixed-use building.

    45 East Central Street, Natick, MA 1760

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    Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 3 Active listings in Natick, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 38 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Upscale Multi-Tenant Commercial Building
    $2,400,000
    11,860 SF
    Upscale Multi-Tenant Commercial Building

    Upscale commercial building with retail, office, and warehouse spaces.

    348 Boston Post, Sudbury, MA 1776

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    Upscale Multi-Tenant Commercial Building
    $2,400,000
    Upscale Multi-Tenant Commercial Building

    Multi-tenant commercial building with retail, office, and warehouse spaces.

    348 Boston Post, Sudbury, MA 1776

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    Mixed-Use Property Near Natick Line
    $1,530,000
    3,487 SF
    Mixed-Use Property Near Natick Line

    Mixed-use property with two-family rental and auto repair potential.

    12-14 Waverly Street, Framingham, MA 1702

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    Framingham Mixed-Use Retail Property
    $3,155,000
    10,240 SF
    Framingham Mixed-Use Retail Property

    10,240 SqFt mixed-use retail and office property for sale.

    665 Cochituate Rd, Framingham, MA 1701

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Natick Land Development Opportunity
    $2,399,000
    0.71 Acres
    Natick Land Development Opportunity

    Land package in Natick's Gateway Center Zoning District.

    67 E Central St & 5 Union St, Natick, MA 1760

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    Natick Development Opportunity
    $2,399,000
    0.71 Acres
    Natick Development Opportunity

    Land package in Natick's Gateway Center Zoning District.

    67 E Central St & 5 Union St, Natick, MA 1760

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    Natick Land Development Opportunity
    $2,399,000
    0.71 Acres
    Natick Land Development Opportunity

    Land package in Natick's Gateway Center Zoning District.

    67 E Central Street & 5 Union Street, Natick, MA 1760

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    Natick Redevelopment Opportunity
    $7,200,000
    3.00 Acres
    Natick Redevelopment Opportunity

    3 acres with redevelopment potential in Natick, Massachusetts.

    21 Eliot St, Natick, MA 1760

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    Off-Market Properties in Natick, MA

    Consider similar Off-Market properties in Natick, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    54 Eliot St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,301 SF Lot: 0.19 Acres
    Estimated value
    $1,285,000

    54 Eliot St, Natick, MA 01760

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    49 Summer St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,230 SF Lot: 0.19 Acres

    49 Summer St, Natick, MA 01760-4521

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    30 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    5,112 SF Lot: 0.24 Acres
    Value Estimation by Request

    30 Main St, Natick, MA 01760-3422

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    25 Central St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,766 SF Lot: 0.23 Acres
    Estimated value
    $625,000

    25 Central St, Natick, MA 01760-4550

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    303 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    1,838 SF Lot: 0.76 Acres
    Value Estimation by Request

    303 Main St, Natick, MA 01760-1118

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    987 Worcester St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,170 SF Lot: 0.26 Acres
    Value Estimation by Request

    987 Worcester St, Natick, MA 01760-2032

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    17 Cochituate St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,730 SF Lot: 0.13 Acres
    Value Estimation by Request

    17 Cochituate St, Natick, MA 01760-3486

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    254 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,464 SF Lot: 0.11 Acres
    Value Estimation by Request

    254 Main St, Natick, MA 01760-1152

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    991 Worcester St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,158 SF Lot: 0.38 Acres
    Value Estimation by Request

    991 Worcester St, Natick, MA 01760-2032

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    295 Bacon St
    OFFICE/RESIDENTIAL (MIXED USE)
    3,388 SF Lot: 0.45 Acres
    Estimated value
    $760,000

    295 Bacon St, Natick, MA 01760-2088

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    161 Pond St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,409 SF Lot: 0.33 Acres
    Estimated value
    $505,000

    161 Pond St, Natick, MA 01760-4320

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    59 Summer St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,557 SF Lot: 0.13 Acres
    Estimated value
    $675,000

    59 Summer St, Natick, MA 01760-4521

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    29 Central St
    OFFICE/RESIDENTIAL (MIXED USE)
    2,527 SF Lot: 0.22 Acres
    Estimated value
    $505,000

    29 Central St, Natick, MA 01760-4501

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    4 Wellesley Rd
    OFFICE/RESIDENTIAL (MIXED USE)
    2,578 SF Lot: 0.14 Acres
    Value Estimation by Request

    4 Wellesley Rd, Natick, MA 01760-1428

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    31 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    45,676 SF Lot: 0.57 Acres
    Estimated value
    $6,940,000

    31 Main St, Natick, MA 01760-4960

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    1 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    7,404 SF Lot: 0.09 Acres
    Estimated value
    $1,065,000

    1 Main St, Natick, MA 01760-3403

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    13 Central St
    OFFICE/RESIDENTIAL (MIXED USE)
    26,780 SF Lot: 0.32 Acres
    Estimated value
    $3,950,000

    13 Central St, Natick, MA 01760-4560

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    39 Main St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,514 SF Lot: 0.16 Acres
    Estimated value
    $685,000

    39 Main St, Natick, MA 01760-4948

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    6 Dewey St
    OFFICE/RESIDENTIAL (MIXED USE)
    3,012 SF Lot: 0.25 Acres
    Estimated value
    $545,000

    6 Dewey St, Natick, MA 01760-4602

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    41 Central St
    OFFICE/RESIDENTIAL (MIXED USE)
    4,368 SF Lot: 0.17 Acres
    Estimated value
    $740,000

    41 Central St, Natick, MA 01760-4503

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    45 Central St
    OFFICE/RESIDENTIAL (MIXED USE)
    3,960 SF Lot: 0.39 Acres
    Estimated value
    $680,000

    45 Central St, Natick, MA 01760-4503

    View details

    Natick, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 41 mixed-use properties for sale in Natick, MA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 117,922 square feet of properties for sale, with an estimated market value of $1,199,000.

    Sale prices for multi use buildings in Natick, MA start at $0.00, averaging $399,666, and reaching up to $1,199,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Property Size Breakdown

    The majority of commercial real estate listings in Natick fall within the 100,000+ square foot range.

    Demographics Overview

    Population 37K
    Population Growth (5Y) +2.1%
    Median Household Income $134,644

    High-Yield Neighborhoods for Investment

    Identify Natick submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    01760 $1.2M

    Taxes & Financing

    Tax Rate (average for all types) 1.23%
    Property Tax per SF $11.62 per sq ft
    Tax Rate vs County Average 0.54 pp below county avg
    Average Loan-to-Value 65.0%

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