Mixed-Use

Natick, MA Mixed-use Properties for Sale

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Wellesley, MA Framingham, MA Wayland, MA Sherborn, MA Weston, MA Needham, MA Dover, MA Ashland, MA
Downtown Natick Retail Opportunity
Updated: Nov 21, 2025
Downtown Natick Retail Opportunity

21 Summer Street, Natick, MA 01760

Contact for pricing
28,422 sqft
Prime location in Downtown Natick, across from The Center for Arts in Natick (TCAN), attracting approximately 30,000 patrons annually.
Up to 4,800 square feet of street‑level retail space in a newly developed mixed‑use building (Year Built: 2024).
Well‑suited for a restaurant with a ventilation shaft for a 16' hood and a partial open‑air concept dining room.
Located steps from Natick Common, with high visibility and accessibility to dining, shopping, and entertainment.
Convenient transportation via the Natick Center MBTA Commuter Rail station, providing access to Boston.
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Downtown Natick Mixed-Use Building
Updated: Nov 21, 2025
Downtown Natick Mixed-Use Building

45 East Central Street, Natick, MA 01760

Contact for pricing
89,500 sqft
Prime downtown Natick location with high visibility and foot traffic.
Newly developed mixed‑use building with 46 residential units providing built‑in customer base.
Flexible space options available from 1,500 to 6,000± square feet, suitable for various uses.
Permitted uses include restaurant (with outdoor seating), retail, office, medical, education, and showroom.
Close proximity to Natick Common, local dining, shopping, and entertainment.
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Natick Center Redevelopment Opportunity
Natick Center Redevelopment Opportunity

49 Summer, Natick, MA 01760

$1,199,000
0.19 AC lot

Two-family house plus detached commercial/retail building in Natick Center.

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Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 3 Active listings in Natick, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 38 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Property Near Commuter Rail
Mixed-Use Property Near Commuter Rail

12 & 14 Waverly St, Framingham, MA 01702

$1,530,000
0.22 AC lot

Mixed-use property with auto repair potential near commuter rail.

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Mixed-Use Building Near Moody Street
Mixed-Use Building Near Moody Street

55-57 Crescent Street, Waltham, MA 02453

$2,399,000
4,585 sqft

Mixed-use property with residential, rooming house, and salon spaces.

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Framingham Mixed-Use Retail Property
Framingham Mixed-Use Retail Property

665 Cochituate Rd, Framingham, MA 01701

$3,637,000
10,240 sqft

10,240 SqFt mixed-use retail and office property for sale.

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Mixed-Use Building in Downtown Waltham
Mixed-Use Building in Downtown Waltham

605-607 Main St, Waltham, MA 02452

$2,100,000

Mixed-use commercial/residential building in downtown Waltham, great investment opportunity.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Natick Redevelopment Opportunity
Natick Redevelopment Opportunity

21 Eliot St, Natick, MA 01760

$7,200,000
3.00 AC lot

3 acres with redevelopment potential in Natick, Massachusetts.

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Auburndale Village VC2-Zoned Land
Auburndale Village VC2-Zoned Land

283 Melrose St, Newton, MA 02466

$8,999,000

Rare opportunity for housing and mixed-use development in Newton.

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Versatile Land Parcel in Upton
Versatile Land Parcel in Upton

W Main St lot: 108, Upton, MA 01568

$550,000
5.45 AC lot

5.45 acre commercial land parcel with development potential.

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Prime Development Land in Boylston
Prime Development Land in Boylston

50 Shrewsbury St, Boylston, MA 01505

$2,750,000
12.59 AC lot

Exceptional 12.59-acre development site with high visibility and accessibility.

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Off-Market Properties in Natick, MA

Consider similar Off-Market properties in Natick, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

54 Eliot St
OFFICE/RESIDENTIAL (MIXED USE)

54 Eliot St, Natick, MA 01760

$1,285,000
Estimated value
4,301 sqft 0.19 AC lot
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49 Summer St
OFFICE/RESIDENTIAL (MIXED USE)

49 Summer St, Natick, MA 01760-4521

$640,000
Estimated value
4,230 sqft 0.19 AC lot
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30 Main St
OFFICE/RESIDENTIAL (MIXED USE)

30 Main St, Natick, MA 01760-3422

Value Estimation by Request
5,112 sqft 0.24 AC lot
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25 Central St
OFFICE/RESIDENTIAL (MIXED USE)

25 Central St, Natick, MA 01760-4550

$625,000
Estimated value
2,766 sqft 0.23 AC lot
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303 Main St
OFFICE/RESIDENTIAL (MIXED USE)

303 Main St, Natick, MA 01760-1118

Value Estimation by Request
1,838 sqft 0.76 AC lot
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987 Worcester St
OFFICE/RESIDENTIAL (MIXED USE)

987 Worcester St, Natick, MA 01760-2032

Value Estimation by Request
2,170 sqft 0.26 AC lot
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17 Cochituate St
OFFICE/RESIDENTIAL (MIXED USE)

17 Cochituate St, Natick, MA 01760-3486

Value Estimation by Request
2,730 sqft 0.13 AC lot
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254 Main St
OFFICE/RESIDENTIAL (MIXED USE)

254 Main St, Natick, MA 01760-1152

Value Estimation by Request
2,464 sqft 0.11 AC lot
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991 Worcester St
OFFICE/RESIDENTIAL (MIXED USE)

991 Worcester St, Natick, MA 01760-2032

Value Estimation by Request
4,158 sqft 0.38 AC lot
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295 Bacon St
OFFICE/RESIDENTIAL (MIXED USE)

295 Bacon St, Natick, MA 01760-2088

$760,000
Estimated value
3,388 sqft 0.45 AC lot
View details
161 Pond St
OFFICE/RESIDENTIAL (MIXED USE)

161 Pond St, Natick, MA 01760-4320

$505,000
Estimated value
2,409 sqft 0.33 AC lot
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59 Summer St
OFFICE/RESIDENTIAL (MIXED USE)

59 Summer St, Natick, MA 01760-4521

$675,000
Estimated value
4,557 sqft 0.13 AC lot
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29 Central St
OFFICE/RESIDENTIAL (MIXED USE)

29 Central St, Natick, MA 01760-4501

$505,000
Estimated value
2,527 sqft 0.22 AC lot
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4 Wellesley Rd
OFFICE/RESIDENTIAL (MIXED USE)

4 Wellesley Rd, Natick, MA 01760-1428

Value Estimation by Request
2,578 sqft 0.14 AC lot
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31 Main St
OFFICE/RESIDENTIAL (MIXED USE)

31 Main St, Natick, MA 01760-4960

$6,940,000
Estimated value
45,676 sqft 0.57 AC lot
View details
1 Main St
OFFICE/RESIDENTIAL (MIXED USE)

1 Main St, Natick, MA 01760-3403

$1,065,000
Estimated value
7,404 sqft 0.09 AC lot
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13 Central St
OFFICE/RESIDENTIAL (MIXED USE)

13 Central St, Natick, MA 01760-4560

$3,950,000
Estimated value
26,780 sqft 0.32 AC lot
View details
39 Main St
OFFICE/RESIDENTIAL (MIXED USE)

39 Main St, Natick, MA 01760-4948

$685,000
Estimated value
4,514 sqft 0.16 AC lot
View details
6 Dewey St
OFFICE/RESIDENTIAL (MIXED USE)

6 Dewey St, Natick, MA 01760-4602

$545,000
Estimated value
3,012 sqft 0.25 AC lot
View details
41 Central St
OFFICE/RESIDENTIAL (MIXED USE)

41 Central St, Natick, MA 01760-4503

$740,000
Estimated value
4,368 sqft 0.17 AC lot
View details
45 Central St
OFFICE/RESIDENTIAL (MIXED USE)

45 Central St, Natick, MA 01760-4503

$680,000
Estimated value
3,960 sqft 0.39 AC lot
View details

Natick, MA Mixed-Use Properties Market Trends and Statistics

Explore 41 mixed-use properties for sale in Natick, MA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 117,922 square feet of properties for sale, with an estimated market value of $1,199,000.

Sale prices for multi use buildings in Natick, MA start at $0.00, averaging $399,666, and reaching up to $1,199,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 37K
Population Growth (5Y) +2.1%
Median Household Income $134,644

High-Yield Neighborhoods for Investment

Identify Natick submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
01760 $1.2M

Taxes & Financing

Tax Rate (average for all types) 1.23%
Property Tax per SF $11.62 per SF
Tax Rate vs County Average 0.54 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Middlesex County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Natick fall within the 100,000+ square foot range.

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