Add Listing
    Des Moines, IA
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Des Moines, IA Office Units for Lease

    Notify Me
    List
    Map
    Urbandale, IA Windsor Heights, IA Clive, IA
    63 results
    Office Space Near Sculpture Park
    $12 SF/Yr
    6,401 SF

    Office Space Near Sculpture Park

    1300 Walnut Street, Des Moines, IA 50309

    Office space for rent near downtown Des Moines attractions.

    • Prime location within walking distance to numerous restaurants and attractions.
    • Open ceilings with exposed brick and large windows.
    • Close proximity to Pappajohn Sculpture Garden.
    • Nearby parking garage available for tenant parking.
    • Tenant improvements available.
    Updated: Mar 25
    View details
    Des Moines Flex/Industrial Building
    Contact for pricing
    15,034 SF

    Des Moines Flex/Industrial Building

    1801 2nd Ave, Des Moines, IA 50314

    15,034 SF office/warehouse on 1.18-acre lot.

    • High‑visibility location on 2nd Avenue corridor with 16,000+ vehicles passing daily.
    • 15,034 SF standalone office/warehouse building suitable for owner‑users or investors.
    • 1.18‑acre lot with ample off‑street parking.
    • City of Des Moines' 2nd Avenue Reconstruction project (completion in 2026) will enhance accessibility and long‑term asset value.
    • Includes both drive‑in (10x12) and dock‑high (8x10) doors.
    Updated: Mar 6
    View details
    Historic Office Space For Lease
    $10 SF/Yr
    2,208 SF

    Historic Office Space For Lease

    Historic office condo in vibrant Court Avenue District available for lease.

    100 Court Avenue, Des Moines, IA 50309
    View details
    Versatile Corporate Headquarters Location
    $8 SF/Yr
    36,071 SF

    Versatile Corporate Headquarters Location

    Adaptable spaces with convenient access and nearby amenities.

    535 Southwest 7th Street, Des Moines, IA 50309
    View details
    Des Moines Office Space Available
    $20 SF/Yr
    6,228 SF

    Des Moines Office Space Available

    6,228 SF office space for sublease in Des Moines.

    220 SW 9th St, Des Moines, IA
    View details
    East Village Contemporary Office Space
    $14 SF/Yr
    10,401 SF

    East Village Contemporary Office Space

    Modern 10,401 SF office in vibrant urban environment.

    505 East Grand Avenue, Des Moines, IA 50309
    View details
    Des Moines Office Space Available
    $22 SF/Yr
    7,516 SF

    Des Moines Office Space Available

    Office space for rent with convenient parking and highway access.

    601 East Locust Street, Des Moines, IA 50309
    View details
    Downtown Des Moines Office Space
    Contact for pricing
    2,500 SF

    Downtown Des Moines Office Space

    Office space for rent in historic downtown Des Moines.

    108 3rd St, Des Moines, IA 50309
    View details
    Des Moines Retail/Office Space
    Contact for pricing
    1,820 SF

    Des Moines Retail/Office Space

    Retail or office space for lease in Des Moines.

    2619 Southwest 9th Street, Des Moines, IA 50315
    View details
    Grand Avenue Office Space Available
    $10 SF/Yr
    8,971 SF

    Grand Avenue Office Space Available

    Highly visible office building in the Grand Avenue corridor.

    2141 Grand Avenue, Des Moines, IA 50312
    View details
    Des Moines Office Space Available
    Contact for pricing
    6,602 SF

    Des Moines Office Space Available

    6,602 SF office space for lease or sale.

    5001 Southwest 9th Street, Des Moines, IA 50315
    View details
    Ingersoll Avenue Mixed-Use Office Space
    $16 SF/Yr
    2,000 SF

    Ingersoll Avenue Mixed-Use Office Space

    Mixed-use building with office space for rent on Ingersoll Avenue.

    3706 Ingersoll Avenue, Des Moines, IA 50312
    View details
    Visible Office Space on Merle Hay
    $11 SF/Yr
    25,088 SF

    Visible Office Space on Merle Hay

    Highly visible office space with utilities included on Merle Hay.

    4725 Merle Hay Road, Des Moines, IA 50322
    View details
    Restored Historic Building Office Space
    $650/Mo
    5,198 SF

    Restored Historic Building Office Space

    Flexible office space in a beautifully restored historic building.

    1163 24th St, Des Moines, IA 50311
    View details
    Industrial Space Near I-80/35
    $4 SF/Yr

    Industrial Space Near I-80/35

    Industrial space with office in Des Moines near I-80/35.

    1550 East Washington Avenue, Des Moines, IA 50316
    View details
    Retail and Office Space Available
    Contact for pricing
    1,649 SF

    Retail and Office Space Available

    Retail and office space for lease, available summer 2026.

    3121 Ingersoll Ave, Des Moines, IA 50312
    View details
    Office Space on Hickman Road
    $12 SF/Yr
    27,336 SF

    Office Space on Hickman Road

    Value office space for lease in Clive, Iowa.

    8350 Hickman Road, Des Moines, IA 50325
    View details
    Des Moines Landmark Lofts
    $18 SF/Yr
    17,373 SF

    Des Moines Landmark Lofts

    Renovated lofts with ground floor commercial space in Des Moines.

    717 Locust Street, Des Moines, IA 50309
    View details
    Class A+ Office Space
    $24 SF/Yr
    4,182 SF

    Class A+ Office Space

    Premier office location with river views and modern amenities.

    110 E Court Ave, Des Moines, IA 50309
    View details
    Des Moines Office Space Available
    $14 SF/Yr
    7,576 SF

    Des Moines Office Space Available

    7576 square foot office space for rent.

    304 15th Street, Des Moines, IA 50309
    View details
    Downtown Des Moines Office Space
    $18 SF/Yr
    3,906 SF

    Downtown Des Moines Office Space

    Office space for rent in historic Insurance Exchange Building.

    501 5th Ave, Des Moines, IA
    View details
    Divisible Warehouse Space Available
    Contact for pricing
    8,000 SF

    Divisible Warehouse Space Available

    Up to 145,000 RSF available with shared access.

    1901 Bell Ave, Des Moines, IA 50315
    View details
    Industrial Shop Near I-35/80
    Contact for pricing
    5,817 SF

    Industrial Shop Near I-35/80

    5,817 SF industrial shop with desirable features for rent.

    3839 Delaware Ave, Des Moines, IA 50313
    View details
    Des Moines Office Space Available
    Contact for pricing
    3,099 SF

    Des Moines Office Space Available

    Office space featuring private offices, conference room, and kitchenette.

    601 Forest Ave, Des Moines, IA
    View details

    Des Moines, IA Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Des Moines, IA with 63 listings featured on our commercial real estate exchange. The current inventory includes 243,113 square feet of properties with an estimated lease value of $440 /Mo.

    Estimated lease rates for Office Units in Des Moines, IA begin at $1.50 SF/Yr, with an average of $14 SF/Yr and extend to $24 SF/Yr.
    List
    Map

    Popular Searches in Des Moines, IA

    Popular Categories

    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50312
    • 50315
    • 50311
    • 50313
    • 50325
    • 50266
    • 50310
    • 50314
    • 50316
    • 50321

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!