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    Des Moines, IA Office Buildings for Lease

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    West Des Moines, IA Cedar Rapids, IA Ankeny, IA
    28 results
    Downtown Des Moines Office Space
    $19 SF/Yr
    14,360 SF

    Downtown Des Moines Office Space

    500 Southwest 7th Street, Des Moines, IA 50309

    Three-story office building in vibrant Riverpoint district with parking.

    • Lowest fully serviced lease rate available for comparable downtown properties.
    • Free on‑site surface parking available.
    • Up to 14,360 SF of Contiguous Space.
    • Centrally located South of Des Moines’ Central Business District, adjacent to new living and retail amenities.
    • Attractive open foyer providing an abundance of natural light.
    Updated: Mar 25
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    Historic Office Building in Des Moines
    $17 SF/Yr
    7,689 SF

    Historic Office Building in Des Moines

    1420 Locust Street, Des Moines, IA 50309

    Two-story office building with unique architecture and high-end finishes.

    • Prime Downtown Des Moines location adjacent to Pappajohn Sculpture Park and Western Gateway Park.
    • Unique architecture and high‑end finishes.
    • Historic, mixed‑use building with attractive glass and masonry storefront.
    • Onsite parking.
    • Tall, exposed ceilings and ample natural light.
    Updated: Mar 25
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    Class A Office Retail Building
    $8 SF/Yr
    158,557 SF

    Class A Office Retail Building

    Eight-story Class A office and retail building in downtown Des Moines.

    400 Locust Street, Des Moines, IA 50309
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    Premier Riverfront Office and Retail
    Contact for pricing
    1,643 SF

    Premier Riverfront Office and Retail

    Class A+ office and retail space in Des Moines' East Village.

    110 E Court Ave, Des Moines, IA 50309
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    Des Moines Office/Warehouse Opportunity
    Contact for pricing
    29,480 SF

    Des Moines Office/Warehouse Opportunity

    29,342 SF building on 2.275 acres for sale/lease.

    2701 Delaware Ave, Des Moines, IA 50317
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    Des Moines Office Space Available
    $9 SF/Yr
    86,892 SF

    Des Moines Office Space Available

    Office building with high visibility and convenient highway access.

    1500 Northwest 118th Street, Des Moines, IA 50325
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    Renovated Market District Office Building
    Contact for pricing
    33,792 SF

    Renovated Market District Office Building

    Creative office space in the heart of the Market District.

    118 Southeast 4th Street, Des Moines, IA 50309
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    Two-Story Building on Corner Lot
    $33 SF/Yr
    5,496 SF

    Two-Story Building on Corner Lot

    5,496 SF building suitable for office, retail, or restaurant.

    2120 Ingersoll Ave, Des Moines, IA
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    Downtown Des Moines Office Space
    Contact for pricing
    30,210 SF

    Downtown Des Moines Office Space

    Office space with downtown views and interstate access.

    777 3rd Street, Des Moines, IA 50309
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    Grand Avenue Office Building
    $20 SF/Yr
    90,223 SF

    Grand Avenue Office Building

    Five-story office building in DMU32 Health and Business Complex.

    3440 Grand Avenue, Des Moines, IA 50312
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    Modern Space in DMU32 Complex
    Contact for pricing
    152,854 SF

    Modern Space in DMU32 Complex

    152,854 SF building with flexible space and amenities.

    3300 Grand Avenue, Des Moines, IA 50312
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    Modern Office Space Available
    Contact for pricing
    31,199 SF

    Modern Office Space Available

    Six-story office building with modern design and collaborative spaces.

    1459 Grand Ave, Des Moines, IA
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    Class A Office Building
    Contact for pricing
    22,262 SF

    Class A Office Building

    Seven-story Class A office building in Downtown Des Moines.

    1150 Locust Street, Des Moines, IA 50391
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    Des Moines Office Building For Sale
    Contact for pricing
    8,446 SF

    Des Moines Office Building For Sale

    Office building with ample parking and convenient location for sale.

    5601 Douglas Ave, Des Moines, IA
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    Downtown Des Moines Office Space
    Contact for pricing

    Downtown Des Moines Office Space

    Historic three-story office building with high-end finishes and parking.

    1440 Locust St, Des Moines, IA 50309
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    Class A Office Space Available
    Contact for pricing
    22,262 SF

    Class A Office Space Available

    Class A office space for rent in downtown Des Moines.

    1100-1150 Locust St, Des Moines, IA
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    Visible Office Space For Lease
    Contact for pricing
    20,000 SF

    Visible Office Space For Lease

    20,000 SF office space near stadium and Market District.

    113 SW 8th St, Des Moines, IA 50309
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    Class A Office Building
    $20 SF/Yr
    15,518 SF

    Class A Office Building

    Class A office building with skywalk access and on-site security.

    699 Walnut St, Des Moines, IA 50309
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    Historic Des Moines Mixed-Use Building
    Contact for pricing

    Historic Des Moines Mixed-Use Building

    Renovated mixed-use building with apartments and commercial space.

    405 6th Ave, Des Moines, IA 50309
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    Renovated Market District Office Building
    Contact for pricing
    33,792 SF

    Renovated Market District Office Building

    33,792 SF renovated office building in the Market District.

    118 SE 4th St, Des Moines, IA 50309
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    Class A Office Building
    Contact for pricing

    Class A Office Building

    Attractive office building with professional management and convenient location.

    2700 Grand Ave, Des Moines, IA 50312
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    Renovated Office Building with Parking
    $15 SF/Yr
    14,856 SF

    Renovated Office Building with Parking

    Historically renovated office building in the heart of Des Moines.

    213 13th St, Des Moines, IA
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    Historic Office Building on Walnut
    Contact for pricing

    Historic Office Building on Walnut

    Located in the Western Gateway of Des Moines cultural corridor.

    1300 Walnut St, Des Moines, IA 50319
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    Modern Office Building in East Village
    Contact for pricing

    Modern Office Building in East Village

    Three-story office building with on-site parking in the East Village.

    300 E Locust St, Des Moines, IA 50309
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    Des Moines, IA Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Des Moines, IA with 28 listings featured on our commercial real estate exchange. The current inventory includes 15,582,326,760 square feet of properties with an estimated lease value of $74 SF/Yr.

    Estimated lease rates for Office buildings in Des Moines, IA begin at $8 SF/Yr, with an average of $14 SF/Yr and extend to $20 SF/Yr.
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    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50312
    • 50317
    • 50319
    • 50325
    • 50391

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