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    Leesburg, FL Office Spaces for Lease

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    Fruitland Park, FL Groveland, FL Lady Lake, FL
    22 results
    Leesburg Office Space Available
    $3,000/Mo
    9,800 SF
    Leesburg Office Space Available

    401 E NORTH BOULEVARD, Leesburg, FL 34748

    Two office units available, suitable for various businesses.
    • Prime location near downtown Leesburg and the hospital, with easy access via 441 frontage.
    • Ample parking available for over 60 vehicles.
    • Two 2000 sq ft units available, connectable for a total of 4000 sq ft.
    • Existing layout includes reception areas, exam rooms, and waiting rooms, suitable for various businesses.
    • Monthly rent includes CAM and taxes.
    Updated: Feb 25
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    Medical Office Near UF Health
    $26 SF/Yr
    8,642 SF
    Medical Office Near UF Health

    640 S LAKE STREET, Leesburg, FL 34748

    Medical office space for lease near UF Health Leesburg Hospital.
    • Directly across from UF Health Leesburg Hospital in a key medical hub.
    • 4,072 SQFT medical office space zoned C‑2.
    • Features eight exam rooms, multiple private offices, and a dedicated surgery room with private waiting room.
    • Abundant parking with 44+ spaces.
    • Recently replaced roof (3 years ago).
    Updated: Oct 6, 2025
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    Leesburg Mixed-Use Highway Frontage
    $1,850/Mo
    5,400 SF
    Leesburg Mixed-Use Highway Frontage

    Updated mixed-use building with high visibility on US Highway 441.

    1539 US HIGHWAY 441, Leesburg, FL 34748

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    Leesburg Warehouse with Office Space
    $60,000 SF/Yr
    5,000 SF
    Leesburg Warehouse with Office Space

    5,000 SF warehouse with office space for lease.

    118 WEBER Ave, Leesburg, FL 34748

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    Modern Warehouses with Fenced Land
    $122,040 SF/Yr
    10,170 SF
    Modern Warehouses with Fenced Land

    Two modern, air-conditioned warehouses totaling 10,170 SF on 0.92 acres.

    1818 GREENLEAF Ln, Leesburg, FL 34748

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    Leesburg Office/Warehouse Flex Space
    $19,040/Mo
    10,500 SF
    Leesburg Office/Warehouse Flex Space

    Office and warehouse space for lease in Greenleaf Business Center.

    1805 GREENLEAF Ln, Leesburg, FL 34748

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    Leesburg Industrial/Warehouse Space Available
    $93,800 SF/Yr
    13,400 SF
    Leesburg Industrial/Warehouse Space Available

    Industrial/Warehouse space for lease in Leesburg, Florida.

    2317 GRIFFIN Rd, Leesburg, FL 34748

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    Leesburg Commercial Space For Lease
    $2.00 SF/Yr
    4,520 SF
    Leesburg Commercial Space For Lease

    4,520 sq ft space suitable for various uses.

    1314 SUMTER St, Leesburg, FL 34748

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    Downtown Leesburg Corner Unit
    $21,806 SF/Yr
    1,200 SF
    Downtown Leesburg Corner Unit

    Prime retail/office space in thriving downtown Leesburg.

    200 W MAIN St, Leesburg, FL 34748

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    Leesburg Warehouse with Air Conditioning
    $80,400 SF/Yr
    8,040 SF
    Leesburg Warehouse with Air Conditioning

    8,040 sq ft fully air conditioned warehouse for lease.

    125 MONTCLAIR Rd 2, Leesburg, FL 34748

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    Highway Frontage Retail/Office Space
    $22,200 SF/Yr
    784 SF
    Highway Frontage Retail/Office Space

    Updated retail/office space with high visibility on US Highway 441.

    1539 US HIGHWAY 441, Leesburg, FL 34748

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    Leesburg Office Space Available
    $53,900 SF/Yr
    8,036 SF
    Leesburg Office Space Available

    Office space for rent in Leesburg, Florida.

    300 RICHEY ROAD 3 & 4, Leesburg, FL 34748

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    Renovated Office Space For Rent
    $24,000 SF/Yr
    1,500 SF
    Renovated Office Space For Rent

    Newly renovated office space on a high-traffic corridor.

    1130 E NORTH Blvd, Leesburg, FL 34748

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    Leesburg Warehouse and Office Space
    $53,900 SF/Yr
    1,925 SF
    Leesburg Warehouse and Office Space

    Warehouse and office units with secure storage yard for lease.

    300 RICHEY Rd 3 & 4, Leesburg, FL 34748

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    Downtown Leesburg Studio Office Space
    $17,400/Mo
    Downtown Leesburg Studio Office Space

    Two-room studio office in downtown Leesburg, ideal for creatives.

    103 S 2ND St C, Leesburg, FL 34748

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    Leesburg Warehouse and Office Space
    Contact for pricing
    90,500 SF
    Leesburg Warehouse and Office Space

    Warehouse and office space with highway access in Leesburg, FL.

    3301 West Main Street, Leesburg, FL 34748

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    Turn-Key Medical Office Building
    $135,198 SF/Yr
    7,511 SF
    Turn-Key Medical Office Building

    Medical office building near UF Health Hospital in Leesburg.

    1414 E MAIN STREET, Leesburg, FL 34748

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    Medical Office Space Available
    Contact for pricing
    5,396 SF
    Medical Office Space Available

    Move-in ready, renovated medical suites with ample parking.

    600 W North Blvd, Leesburg, FL

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    Retail/Medical Space on Highway 441
    Contact for pricing
    3,375 SF
    Retail/Medical Space on Highway 441

    Retail or medical spaces available on a high-traffic corridor.

    1450 E N Blvd, Leesburg, FL

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    Downtown Leesburg Mixed-Use Space
    Contact for pricing
    15,000 SF
    Downtown Leesburg Mixed-Use Space

    Lease opportunity in growing downtown Leesburg with high traffic.

    410 West Main Street, Leesburg, FL 34748

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    Renovated Office Space Available
    Contact for pricing
    2,504 SF
    Renovated Office Space Available

    Office space for rent with recent renovations and ample parking.

    106 W N Blvd, Leesburg, FL

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    Highway Frontage Commercial Space
    $12 SF/Yr
    546 SF
    Highway Frontage Commercial Space

    Commercial space with highway frontage on US Hwy 441-27.

    2204 Citrus Blvd, Leesburg, FL 34748

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    Based on your search, we've compiled 46 Potential Opportunities for your consideration. Besides 22 Active listings in Leesburg, FL, we suggest exploring alternatives. Similar 24 Properties for Sales.

    Similar Spaces for Sale in Leesburg, FL

    Consider Similar Space for Sale. We found 24 Spaces matching your search parameters.

    Downtown Leesburg Professional Office Building
    $599,000
    2,968 SF
    Downtown Leesburg Professional Office Building

    Well-maintained office building in downtown Leesburg with tenant in place.

    1029 W MAGNOLIA STREET, Leesburg, FL 34748

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    Leesburg Office Building on Highway 441
    $1,250,000
    9,800 SF
    Leesburg Office Building on Highway 441

    9,800 SF medical/professional office building with highway frontage.

    401 E NORTH BOULEVARD, Leesburg, FL 34748

    View details

    Leesburg, FL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Leesburg, FL with 22 listings featured on our commercial real estate exchange. The current inventory includes 86,474 square feet of properties with an estimated lease value of $667,292.

    Estimated lease rates for Office Spaces in Leesburg, FL begin at $2.00 SF/Yr, with an average of $44,486 and extend to $135,198.
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