Lady Lake, FL Medical Office Space for Rent & Lease

Updated: Aug 26

Medical Office Suite with Exam Rooms

757 Hwy 466 Unit 100, Lady Lake, FL 32159

$16 SF/Yr

4,020 sqft

4,020 SF medical office suite built in 2009
12 exam rooms, each equipped with a sink
Reception and waiting area plus executive office
Conference or classroom, lab area, and break room
On‑site parking available

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Updated: Jan 26

New Medical/Professional Shell Spaces

871 Highway 466, Lady Lake, FL 32159

$24 SF/Yr

4,000 sqft

Excellent Visibility & Easy CR 466 Access
BRAND NEW Construction
Generous TI / Tenant Improvement Allowance for Qualified Long Term Tenant
Free Rent to accommodate build‑out
Landlords Builder can complete build‑out in 4 to 6 months

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Lady Lake Office/Medical Space

13912 Us Highway 441 |, Lady Lake, FL 32159

$3,005/Mo

1,803 sqft

Office or medical space available in Lady Lake, Florida.

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Class B+ Medical Office Suite

201 W Guava St, Lady Lake, FL 32159

Contact for pricing

5,598 sqft

Class B+ medical office space in Lady Lake, Florida, ready for healthcare professionals seeking a dedicated office environment.

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Medical Office Suite with Eight Rooms

102103-918 Rolling Acres Rd, Lady Lake, FL 32159

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2,328 sqft

Professional space features a reception area, waiting room, and flexible rooms for office or procedure use.

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New Medical/Professional Shell Spaces

871 HIGHWAY 466, Lady Lake, FL 32159

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4,000 sqft 0.09 AC lot

New construction medical/professional spaces with build-out options and highway access.

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Move-In Ready Medical Office Suites

301 Skyline Dr, Lady Lake, FL 32159

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2,115 sqft

Move-in ready medical/professional suites with flexible build outs near HWY 441 and surrounded by office and medical users.

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Move-In Ready Medical Office Suites

301 Skyline Dr, Lady Lake, FL 32159

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1,294 sqft

Move-in ready medical/professional office suites with flexible sizes, varied build-outs, and convenient parking ratio.

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Medical Office in The Villages

1400 U.S. 441, Lady Lake, FL 32159

$30 SF/Yr

4,932 sqft

Turnkey medical office building on UF Health Spanish Plaines campus.

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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 9 Active listings in Lady Lake, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Building with Elevator

910 Old Camp Rd Unit 110, The Villages, FL 32162

$34 SF/Yr

11,798 sqft

Two-story medical space with elevator access, flexible first-floor layout, and existing treatment and exam room configuration.

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Summerfield Office Space on Highway

17809 SE 109TH Ave, Summerfield, FL 34491

Contact for pricing

2,256 sqft

Highly visible Summerfield office space suitable for medical or professional use.

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Medical/Office Building in The Villages

1503 Buenos Aires Boulevard #150, The Villages, FL 32159

Contact for pricing

3,264 sqft

Standalone medical/office building in The Villages, available February 1, 2026.

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Office or Medical Space Available

17820 SE 109th Ave, Summerfield, FL

Contact for pricing

3,000 sqft 2.57 AC lot

Office or medical space for rent near The Villages.

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Similar Spaces for Sale in Lady Lake, FL

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Medical Office with Exam Rooms

733 County Road 466, Lady Lake, FL 32159

$1,300,000

4,020 sqft

Configured for clinical operations with exam rooms, private offices, reception, and patient waiting space.

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Medical Office Ready For Sale

749 County Road 466, Lady Lake, FL 32159

$599,000

1,920 sqft

Medical/Professional office space for sale in Lady Lake, Florida.

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Move-In Ready Medical Office Property

301 Skyline Dr, Lady Lake, FL 32159

Contact for pricing

10,266 sqft

Two standalone, move-in ready office buildings with recently renovated exterior and an on-site parking ratio of 9/1,000.

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Medical/Professional Office in Lady Lake

301 Skyline Dr, Lady Lake, FL 32159

Contact for pricing

10,266 sqft 1.95 AC lot

Two-building medical/professional office space for sale in Lady Lake.

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NNN Medical Office Unit

809 Co Rd 466, Lady Lake, FL 32159

Contact for pricing

3,105 sqft

Long-term single-tenant NNN lease with Optum Health and 8 years remaining, including annual rent increases.

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NNN Ophthalmology Property

801 Co Rd 466, Lady Lake, FL 32159

$2,428,415

Medical office asset with a remaining NNN lease term exceeding seven years.

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Medical Office Investment Opportunity

737 Hwy 466, Lady Lake, FL 32159

Contact for pricing

1,920 sqft

Leased medical office in growing area near The Villages.

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Lady Lake, FL Medical Office Space Lease Rates & Market Statistics

Browse 9 Medical Office Space listings for lease in Lady Lake, FL on Realmo, a commercial real estate marketplace serving the Lady Lake area. The current inventory totals 30,090 square feet of properties.

Medical Office Space lease rates in Lady Lake range from $16 SF/Yr at the entry level to $30 SF/Yr at the top of the market, averaging $22.50 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $22.50 SF/Yr, the local average runs 23% below Florida's state average of $29.34 SF/Yr.

Lady Lake accounts for 31% of the 29 medical office space listings currently available across Lake County, where nearby markets include Clermont and Leesburg. Medical Office Space listings make up 60% of the 15 Office Spaces currently for lease in Lady Lake, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (9 listings) elsewhere in the Lady Lake market.