Lady Lake, FL Medical Office Space for Lease

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Updated: Feb 26

Lady Lake Office/Medical Space

13912 Us Highway 441 |, Lady Lake, FL 32159

$3,005/Mo

1,803 sqft

Prime location on US Highway 441 with high visibility and accessibility.
Ample parking available for clients and staff.
Well‑maintained building suitable for office or medical practices.
Multiple office spaces to accommodate various business needs.
Professional environment conducive to client interaction and business growth.

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Updated: Nov 10, 2025

Medical Office in The Villages

1400 N US Highway 441, Lady Lake, FL

$30 SF/Yr

4,932 sqft

Prime location on UF Health Spanish Plaines Hospital campus in The Villages.
Turnkey single‑user medical office building.
High visibility on US HWY 441 (41,000 AADT).
Abundant parking (5/1,000 ratio) with cross‑access to UF Health hospital.
Well‑designed layout: Featuring 10 exam rooms, 3 offices, lab, conference room, and a large waiting area.

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Class B+ Medical Office Suite

201 W Guava St, Lady Lake, FL 32159

Contact for pricing

5,598 sqft

Class B+ medical office space in Lady Lake, Florida, ready for healthcare professionals seeking a dedicated office environment.

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Medical Office in Hospital Compound

912-1400 N Us Highway 441, Lady Lake, FL 32159

$53,060 SF/Yr

1,516 sqft

Class A medical office space in Lady Lake, Florida.

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New Medical/Professional Shell Spaces

871 Highway 466, Lady Lake, FL 32159

$48,000 SF/Yr

4,000 sqft

New construction medical/professional spaces with build-out options available.

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Medical Office in The Villages

1400 U.S. 441, Lady Lake, FL 32159

$30 SF/Yr

4,932 sqft

Turnkey medical office building on UF Health Spanish Plaines campus.

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Medical/Professional Suite in Lady Lake

757 HWY 466 100, Lady Lake, FL 32159

$64,320 SF/Yr

4,020 sqft

Medical-ready suite in Summit Medical Park, Lady Lake, Florida.

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Medical Office in Hospital Compound

1400 S US HWY 441, BUILDING 910 912, Lady Lake, FL 32159

$53,060 SF/Yr

Class A medical office space within The Villages Hospital Compound.

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Medical Office in Summit Park

741 Co Rd 466, Lady Lake, FL 32159

$20 SF/Yr

Finished medical office space near UF Health Hospital and The Villages.

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Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 9 Active listings in Lady Lake, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office and Wellness Space

17809 Se 109th Ave, Summerfield, FL 34491

$40,608 SF/Yr

7,034 sqft

Well-suited for medical, wellness, or professional use with a reception area, private office, and breakroom on Highway 441.

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Medical/Office Building in The Villages

1503 Buenos Aires Boulevard #150, The Villages, FL 32159

Contact for pricing

3,264 sqft

Standalone medical/office building in The Villages, available February 1, 2026.

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New Office/Medical/Retail Space Available

17154 SE 109TH TERRACE ROAD, Summerfield, FL 34491

$66,000 SF/Yr

3,000 sqft

3,000 Sq Ft office/medical/retail space near UF Health Hospital.

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Medical/Office Building in The Villages

1503 Buenos Aires Boulevard #150, The Villages, FL 32159

Contact for pricing

Standalone medical/office building in a high-traffic location.

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Similar Spaces for Sale in Lady Lake, FL

Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

Built-Out Medical Office Suite

809 County Road 466, Lady Lake, FL 32159

$1,300,000

3,700 sqft 0.09 AC lot

Move-in-ready corner suite with secure access, multiple procedure rooms, and a split floor plan for flexible office configurations.

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Medical Office in Summit Park

733 COUNTY RD 466, Lady Lake, FL 32159

$1,300,000

4,020 sqft

4,020 SF medical office space in Lady Lake, FL.

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Move-In-Ready Medical Office Suite

202c-809 Highway 466, Lady Lake, FL 32159

$1,300,000

3,700 sqft

Move-in-ready corner unit with split-floor design, procedure rooms, and controlled access for authorized staff.

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Medical/Professional Office in Lady Lake

301 Skyline Dr, Lady Lake, FL 32159

Contact for pricing

10,266 sqft 1.95 AC lot

Two-building medical/professional office space for sale in Lady Lake.

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Medical Office Investment Opportunity

737 Hwy 466, Lady Lake, FL 32159

$700,000

1,920 sqft

Leased medical office in growing area near The Villages.

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Medical Office in Summit Park

737 COUNTY ROAD 466, Lady Lake, FL 32159

$700,000

1,920 sqft 0.12 AC lot

1,920 SF medical office space with new three-year lease.

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Medical Office Ready For Sale

749 Co Rd 466, Lady Lake, FL 32159

$599,000

1,920 sqft

Medical/Professional office space for sale in Lady Lake, Florida.

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Medical/Professional Space in Lady Lake

749 COUNTY ROAD 466, Lady Lake, FL 32159

$619,000

1,920 sqft 0.12 AC lot

Medical-ready/professional space with excellent synergy in a desirable location.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

WINTER PARK Land Lease Opportunity

5589 LAKE HOWELL ROAD, Winter Park, FL 32792

$8,500/Mo

23,056 sqft

Commercial land lease opportunity in Winter Park, Florida.

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Prime Commercial Lot For Rent

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

0.66 acre commercial lot with high visibility.

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Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft

1.7 acre corner lot zoned for commercial, medical, residential.

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Lady Lake, FL Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Lady Lake, FL with 9 listings featured on our commercial real estate exchange. The current inventory includes 21,203 square feet of properties with an estimated lease value of $165,460.

Estimated lease rates for Medical Office Space in Lady Lake, FL begin at $20 SF/Yr, with an average of $27,576 and extend to $64,320.

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