Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Medical Space
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Lady Lake, FL Medical Office Space for Lease

    Notify Me
    List
    Map
    Miami, FL Jacksonville, FL Orlando, FL
    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF

    Medical Office in The Villages

    1400 N US Highway 441, Lady Lake, FL

    Turnkey medical office building on UF Health Spanish Plaines campus.

    • Prime location on UF Health Spanish Plaines Hospital campus in The Villages.
    • Turnkey single‑user medical office building.
    • High visibility on US HWY 441 (41,000 AADT).
    • Abundant parking (5/1,000 ratio) with cross‑access to UF Health hospital.
    • Well‑designed layout: Featuring 10 exam rooms, 3 offices, lab, conference room, and a large waiting area.
    Updated: Nov 10, 2025
    View details
    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF

    Medical Office in The Villages

    1400 U.S. 441, Lady Lake, FL 32159

    Turnkey medical office building on UF Health Spanish Plaines campus.

    • Located on UF Health Spanish Plaines Hospital campus in The Villages.
    • Turnkey single‑user medical office building.
    • High visibility on US HWY 441 (41,000 AADT).
    • Surrounded by other medical practices.
    • Abundant parking plus cross‑access with UF Health hospital.
    Updated: Nov 25, 2025
    View details
    Class A Medical Office Space
    $21 SF/Yr
    2,736 SF

    Class A Medical Office Space

    Medical office space for rent with outpatient surgery center.

    201 W Guava St, Lady Lake, FL
    View details
    Medical/Professional Office in The Villages
    Contact for pricing
    1,944 SF

    Medical/Professional Office in The Villages

    Upscale medical/professional office space for lease in Lady Lake.

    929 US-441, Lady Lake, FL 32159
    View details
    Medical Office in Summit Park
    Contact for pricing

    Medical Office in Summit Park

    Finished medical office space near UF Health Hospital and The Villages.

    741 Co Rd 466, Lady Lake, FL 32159
    View details
    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 5 Active listings in Lady Lake, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Summerfield Office Space on Highway
    $3 SF/Yr
    2,256 SF

    Summerfield Office Space on Highway

    Highly visible Summerfield office space suitable for medical or professional use.

    17809 SE 109TH Ave, Summerfield, FL 34491
    View details
    Medical/Office Building in The Villages
    Contact for pricing

    Medical/Office Building in The Villages

    Standalone medical/office building in a high-traffic location.

    1503 Buenos Aires Boulevard #150, The Villages, FL 32159
    View details
    Medical/Office Building in The Villages
    Contact for pricing
    3,264 SF

    Medical/Office Building in The Villages

    Standalone medical/office building in The Villages, available February 1, 2026.

    1503 Buenos Aires Boulevard #150, The Villages, FL 32159
    View details
    Office or Medical Space Available
    $21 SF/Yr
    3,000 SF

    Office or Medical Space Available

    Office or medical space for rent near The Villages.

    17820 SE 109th Ave, Summerfield, FL
    View details

    Explore Similar Spaces for Sale in Lady Lake, FL

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Luxurious Medical Suite in Lady Lake
    $1,300,000
    0.09 Acres

    Luxurious Medical Suite in Lady Lake

    Move-in-ready medical suite with high-end finishes and flexible layout.

    809 County Road 466, Lady Lake, FL 32159
    View details
    Lady Lake Professional Plaza Office
    $640,000
    2,328 SF

    Lady Lake Professional Plaza Office

    Office space in Lady Lake Professional Plaza available for sale.

    918 ROLLING ACRES, Lady Lake, FL 32159
    View details
    Lady Lake Office Near US-441
    $260,000
    928 SF

    Lady Lake Office Near US-441

    Office space in Lady Lake near The Villages Community.

    918 ROLLING ACRES ROAD, Lady Lake, FL 32159
    View details
    Medical/Professional Space in Lady Lake
    $619,000
    1,920 SF

    Medical/Professional Space in Lady Lake

    Medical-ready/professional space with excellent synergy in a desirable location.

    749 COUNTY ROAD 466, Lady Lake, FL 32159
    View details
    Medical Office in Summit Park
    $700,000
    1,920 SF

    Medical Office in Summit Park

    1,920 SF medical office space with new three-year lease.

    737 COUNTY ROAD 466, Lady Lake, FL 32159
    View details
    Medical/Professional Office in Lady Lake
    Contact for pricing
    10,266 SF

    Medical/Professional Office in Lady Lake

    Two-building medical/professional office space for sale in Lady Lake.

    301 Skyline Dr, Lady Lake, FL 32159
    View details
    Medical Office Investment Opportunity
    $700,000
    1,920 SF

    Medical Office Investment Opportunity

    Leased medical office in growing area near The Villages.

    737 Hwy 466, Lady Lake, FL 32159
    View details
    Medical Office in Lady Lake
    $600,000
    1,920 SF

    Medical Office in Lady Lake

    Fully leased medical office space in a prime location.

    781 Co Rd 466, Lady Lake, FL 32159
    View details
    Medical Office Ready For Sale
    $619,000
    1,920 SF

    Medical Office Ready For Sale

    Medical/Professional office space for sale in Lady Lake, Florida.

    749 Co Rd 466, Lady Lake, FL 32159
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Winter Park Mixed-Use Opportunity
    $8,500 /Mo
    23,056 SF

    Winter Park Mixed-Use Opportunity

    Double commercial lot in Winter Park, FL, for lease.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details

    Lady Lake, FL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Lady Lake, FL with 5 listings featured on our commercial real estate exchange. The current inventory includes 285,492,240 square feet of properties with an estimated lease value of $51 SF/Yr.

    Estimated lease rates for Medical Office Space in Lady Lake, FL begin at $21 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
    List
    Map

    Browse Medical Office Space for Lease Near Lady Lake, FL

    Popular Searches in Lady Lake, FL

    Popular Categories

    Most Searched ZIP Codes in Lady Lake, FL

    • 32159

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!