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    Lady Lake, FL
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    Lady Lake, FL Office Spaces for Lease

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    Fruitland Park, FL The Villages, FL Summerfield, FL
    8 results
    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF
    Medical Office in The Villages

    1400 N US Highway 441, Lady Lake, FL

    Turnkey medical office building on UF Health Spanish Plaines campus.
    • Prime location on UF Health Spanish Plaines Hospital campus in The Villages.
    • Turnkey single‑user medical office building.
    • High visibility on US HWY 441 (41,000 AADT).
    • Abundant parking (5/1,000 ratio) with cross‑access to UF Health hospital.
    • Well‑designed layout: Featuring 10 exam rooms, 3 offices, lab, conference room, and a large waiting area.
    Updated: Nov 10, 2025
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    Lady Lake Office/Medical Space
    Contact for pricing
    1,803 SF
    Lady Lake Office/Medical Space

    13912 Us Highway 441 |, Lady Lake, FL 32159

    Office or medical space available in Lady Lake, Florida.
    • Prime location on US Highway 441 with high visibility and accessibility.
    • Ample parking available for clients and staff.
    • Well‑maintained building suitable for office or medical practices.
    • Multiple office spaces to accommodate various business needs.
    • Professional environment conducive to client interaction and business growth.
    Updated: Feb 26
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    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF
    Medical Office in The Villages

    Turnkey medical office building on UF Health Spanish Plaines campus.

    1400 U.S. 441, Lady Lake, FL 32159

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    Class A Medical Office Space
    $21 SF/Yr
    2,736 SF
    Class A Medical Office Space

    Medical office space for rent with outpatient surgery center.

    201 W Guava St, Lady Lake, FL

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    Stand-Alone Commercial Building For Lease
    Contact for pricing
    2,500 SF
    Stand-Alone Commercial Building For Lease

    2,500 SF stand-alone commercial building with high visibility.

    126 US-441, Lady Lake, FL 32159

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    Medical/Professional Office in The Villages
    $22 SF/Yr
    1,944 SF
    Medical/Professional Office in The Villages

    Upscale medical/professional office space for lease in Lady Lake.

    929 US-441, Lady Lake, FL 32159

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    High-Visibility Retail/Office Space Available
    $25 SF/Yr
    4,000 SF
    High-Visibility Retail/Office Space Available

    Newly completed building with high traffic exposure in The Villages.

    13922 US-441, Lady Lake, FL 32159

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    Medical Office in Summit Park
    $20 SF/Yr
    Medical Office in Summit Park

    Finished medical office space near UF Health Hospital and The Villages.

    741 Co Rd 466, Lady Lake, FL 32159

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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 8 Active listings in Lady Lake, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Summerfield Office Space on Highway
    $3 SF/Yr
    2,256 SF
    Summerfield Office Space on Highway

    Highly visible Summerfield office space suitable for medical or professional use.

    17809 SE 109TH Ave, Summerfield, FL 34491

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    Office or Medical Space Available
    $21 SF/Yr
    3,000 SF
    Office or Medical Space Available

    Office or medical space for rent near The Villages.

    17820 SE 109th Ave, Summerfield, FL

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    Medical/Office Building in The Villages
    Contact for pricing
    Medical/Office Building in The Villages

    Standalone medical/office building in a high-traffic location.

    1503 Buenos Aires Boulevard #150, The Villages, FL 32159

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    Medical/Office Building in The Villages
    Contact for pricing
    3,264 SF
    Medical/Office Building in The Villages

    Standalone medical/office building in The Villages, available February 1, 2026.

    1503 Buenos Aires Boulevard #150, The Villages, FL 32159

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    Similar Spaces for Sale in Lady Lake, FL

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Luxurious Medical Suite in Lady Lake
    $1,300,000
    0.09 Acres
    Luxurious Medical Suite in Lady Lake

    Move-in-ready medical suite with high-end finishes and flexible layout.

    809 County Road 466, Lady Lake, FL 32159

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    Lady Lake Professional Plaza Office
    $640,000
    2,328 SF
    Lady Lake Professional Plaza Office

    Office space in Lady Lake Professional Plaza available for sale.

    918 ROLLING ACRES, Lady Lake, FL 32159

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    Lady Lake Church Property
    $1,825,000
    6,666 SF
    Lady Lake Church Property

    Two buildings on 2.19 acres in Lady Lake area.

    1055 & 1085 TEAGUE Trl, Lady Lake, FL 32159

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    Lady Lake Office Near US-441
    $260,000
    928 SF
    Lady Lake Office Near US-441

    Office space in Lady Lake near The Villages Community.

    918 ROLLING ACRES ROAD, Lady Lake, FL 32159

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    Medical/Professional Space in Lady Lake
    $619,000
    1,920 SF
    Medical/Professional Space in Lady Lake

    Medical-ready/professional space with excellent synergy in a desirable location.

    749 COUNTY ROAD 466, Lady Lake, FL 32159

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    Medical Office in Summit Park
    $700,000
    1,920 SF
    Medical Office in Summit Park

    1,920 SF medical office space with new three-year lease.

    737 COUNTY ROAD 466, Lady Lake, FL 32159

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    Medical/Professional Office in Lady Lake
    Contact for pricing
    10,266 SF
    Medical/Professional Office in Lady Lake

    Two-building medical/professional office space for sale in Lady Lake.

    301 Skyline Dr, Lady Lake, FL 32159

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    Medical Office Investment Opportunity
    $700,000
    1,920 SF
    Medical Office Investment Opportunity

    Leased medical office in growing area near The Villages.

    737 Hwy 466, Lady Lake, FL 32159

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    Medical Office in Lady Lake
    $600,000
    1,920 SF
    Medical Office in Lady Lake

    Fully leased medical office space in a prime location.

    781 Co Rd 466, Lady Lake, FL 32159

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    Medical Office Ready For Sale
    $619,000
    1,920 SF
    Medical Office Ready For Sale

    Medical/Professional office space for sale in Lady Lake, Florida.

    749 Co Rd 466, Lady Lake, FL 32159

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF
    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792

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    Cleared Lot in Williston
    $20,000/Mo
    Cleared Lot in Williston

    C2-zoned lot in Williston's central business area for rent.

    33 NW 3RD St, Williston, FL 32696

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    Downtown Winter Haven Commercial Land
    $29,940 SF/Yr
    Downtown Winter Haven Commercial Land

    City-approved commercial land in a growing business district.

    511 AVENUE G NW, Winter Haven, FL 33881

    View details
    Lakeland Commercial Business Park Spaces
    Contact for pricing
    Lakeland Commercial Business Park Spaces

    Commercial spaces for lease in West Lakeland business park.

    2525 Drane Field Road, Lakeland, FL 33811

    View details

    Lady Lake, FL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Lady Lake, FL with 8 listings featured on our commercial real estate exchange. The current inventory includes 18,544 square feet of properties with an estimated lease value of $128 SF/Yr.

    Estimated lease rates for Office Spaces in Lady Lake, FL begin at $21 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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