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Greenville County, SC Office Buildings for Sale

18 results
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Powdersville Office Building with Retail Potential
$449,000
0.31 Acres

Powdersville Office Building with Retail Potential

3127 Highway 153, Piedmont, SC 29673

2,016 SF office building with retail potential in Powdersville.

  • High‑exposure location with over 200 feet of frontage on Highway 153.
  • Retail potential in addition to office use.
  • Fully handicap accessible with dedicated handicap parking spaces.
  • Median break on Highway 153 allows easy access from both directions.
  • Includes 6 office spaces, 2 restrooms, kitchen, meeting room, and storage.
Updated: Jan 18
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Greenville Office Near Medical Facilities
$950,000
0.35 Acres

Greenville Office Near Medical Facilities

101 Chapman St, Greenville, SC 29605

Premium office space with subdivision potential near Prisma Health.

  • Premium office space in a desirable location
  • Sub‑dividable units suitable for single or multiple tenants
  • Directly across from Prisma Health and USC Medical University
  • Generous parking available
  • Benefit from 10' ceilings
Updated: Nov 24, 2025
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Freestanding Office/Medical Building For Sale
$430,000
2,306 SF

Freestanding Office/Medical Building For Sale

Two-story, 2,306 SF office/medical building in established office park.

4501 Old Spartanburg Rd, Taylors, SC 29687
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Multi-Tenant Office Building For Sale
$1,100,500

Multi-Tenant Office Building For Sale

Multi-tenant office building in Mauldin, SC, for sale.

501 West Butler Rd, Greenville, SC 29607
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Two Office Buildings For Sale
$299,000
1,800 SF

Two Office Buildings For Sale

Two-story office buildings in master-planned park, ideal for investors.

102 Renaissance Cir, Mauldin, SC 29662
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Downtown Greenville Redevelopment Opportunity
$7,000,000
20,000 SF

Downtown Greenville Redevelopment Opportunity

Redevelopment opportunity in Downtown Greenville with mountain views.

1 Alm Way, Greenville, SC 29601
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Office Building For Sale
$6,789,142
34,284 SF

Office Building For Sale

Office building with lease income available for sale.

426 Fairforest Way, Greenville, SC 29607
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Two Greenville Office Buildings For Sale
$2,750,000
16,778 SF

Two Greenville Office Buildings For Sale

Two office buildings with excellent visibility near downtown Greenville.

429 N Main St, Greenville, SC 29601
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Prime Office Property in Greenville
Contact for pricing
2,140 SF

Prime Office Property in Greenville

Modern office space with high visibility and easy access.

102 W Stone Ave, Greenville, SC 29609
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Greenville Office Building For Sale
Contact for pricing
5,288 SF

Greenville Office Building For Sale

Office building with parking near downtown Greenville.

9 Washington Park, Greenville, SC 29601
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Greer Office Building For Sale
Contact for pricing
5,000 SF

Greer Office Building For Sale

Office building in Greer, South Carolina, with recent upgrades.

420 The Pkwy, Greer, SC 29650
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Downtown Office Building For Sale
Contact for pricing
3,444 SF

Downtown Office Building For Sale

Office building with 11 private offices and dedicated parking.

311 Pettigru St, Greenville, SC 29601
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Office Building Near Laurens Road
Contact for pricing
8,030 SF

Office Building Near Laurens Road

Two-story office building with ample parking and updated suite.

8 Sycamore Dr, Greenville, SC 29607
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Renovated Office Building For Sale
Contact for pricing
18,208 SF

Renovated Office Building For Sale

Office building with guaranteed rent by U.S. Government.

319 Pelham Rd, Greenville, SC 29615
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Downtown Owner-Occupant Office Opportunity
Contact for pricing
20,246 SF

Downtown Owner-Occupant Office Opportunity

Downtown office building with great amenities and parking options.

504 Ferguson St, Greenville, SC 29601
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Greenville Office Building For Sale
Contact for pricing
7,000 SF

Greenville Office Building For Sale

Office building with 7,000 square feet of space.

10 Memorial Medical Dr, Greenville, SC 29605
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Greenville Office Building For Sale
Contact for pricing
92,614 SF

Greenville Office Building For Sale

92,614 SF office building on 4.757 acres in Greenville.

216 S Pleasantburg Dr, Greenville, SC 29607
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Highway 101 Office Building
Contact for pricing
12,000 SF

Highway 101 Office Building

Office building with easy access and ample parking.

1431 Highway 101 S, Greer, SC 29651
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 18 Active Listings in Greenville County, SC, we suggest to view alternatives - similar 1783 Off-Market properties to explore as potential leads.

Explore Off-Market Properties in Greenville County, SC

Consider similar Off-Market properties in Greenville County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

66 Saint Mark Rd

66 Saint Mark Rd

OFFICE BUILDING
Value Estimation by Request
66 Saint Mark Rd, Taylors, SC 29687-5233
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3110 Wade Hampton Blvd

3110 Wade Hampton Blvd

OFFICE BUILDING • 0.03 Acres
Value Estimation by Request
3110 Wade Hampton Blvd, Taylors, SC 29687-2863
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Wade Hampton Blvd

Wade Hampton Blvd

OFFICE BUILDING • 1.70 Acres
Value Estimation by Request
Wade Hampton Blvd, Taylors, SC 29687
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300 Old Pelzer Rd

300 Old Pelzer Rd

OFFICE BUILDING • 3.70 Acres
Value Estimation by Request
300 Old Pelzer Rd, Piedmont, SC 29673-8553
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6715 State Park Rd

6715 State Park Rd

OFFICE BUILDING • 0.08 Acres
Value Estimation by Request
6715 State Park Rd, Travelers Rest, SC 29690-1831
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1000 Locust Hl Rd

1000 Locust Hl Rd

OFFICE BUILDING • 0.04 Acres
Value Estimation by Request
1000 Locust Hl Rd, Greer, SC 29651-6013
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Greenville County, SC Office Buildings Investment Opportunities Market Analysis

Explore 1801 office buildings for sale in Greenville County, SC, showcased through 18 active listings on our real estate platform. These investment opportunities span a total of 65,296,451 square feet of properties for sale, with an estimated market value of $811,649,000.

Sale prices for office properties in Greenville County, SC start at $60,000, averaging $782,689, and reaching up to $23,660,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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