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    Greenville County, SC Office Buildings for Sale

    20 results
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    Powdersville Office Building with Retail Potential
    $449,000
    0.31 Acres

    Powdersville Office Building with Retail Potential

    3127 Highway 153, Piedmont, SC 29673

    2,016 SF office building with retail potential in Powdersville.

    • High‑exposure location with over 200 feet of frontage on Highway 153.
    • Retail potential in addition to office use.
    • Fully handicap accessible with dedicated handicap parking spaces.
    • Median break on Highway 153 allows easy access from both directions.
    • Includes 6 office spaces, 2 restrooms, kitchen, meeting room, and storage.
    Updated: Jan 18
    View details
    Updated Office Building in Simpsonville
    $1,800,000
    0.18 Acres

    Updated Office Building in Simpsonville

    131 SE Main St, Simpsonville, SC 29691

    Updated 2,907 SF building in the heart of Downtown Simpsonville.

    • Prime Main Street location in Downtown Simpsonville with high visibility and foot traffic.
    • Zoned B‑U, offering incredible mixed‑use potential (commercial, office, or residential).
    • 13 on‑site parking spaces on a 0.18‑acre lot with expansion potential.
    • Updated 2,907 sq ft building with 5 offices, boardroom, 2 bathrooms, and updated kitchen/break area.
    • Historic charm with original windows, 10‑foot ceilings, and heart pine floors.
    Updated: Jul 21, 2025
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    Greenville Office Near Medical Facilities
    $950,000
    0.35 Acres

    Greenville Office Near Medical Facilities

    Premium office space with subdivision potential near Prisma Health.

    101 Chapman St, Greenville, SC 29605
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    Refreshed Office Building in Greenville
    Contact for pricing
    0.12 Acres

    Refreshed Office Building in Greenville

    Refreshed commercial office building in a prime Greenville location.

    604 University Rdg, Greenville, SC 29601
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    Office Building For Sale
    $6,789,142
    34,284 SF

    Office Building For Sale

    Office building with lease income available for sale.

    426 Fairforest Way, Greenville, SC 29607
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    Downtown Owner-Occupant Office Opportunity
    $7,000,000
    20,246 SF

    Downtown Owner-Occupant Office Opportunity

    Downtown office building with great amenities and parking options.

    504 Ferguson St, Greenville, SC 29601
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    Greenville Office Building For Sale
    $825,000
    7,000 SF

    Greenville Office Building For Sale

    Office building with 7,000 square feet of space.

    10 Memorial Medical Dr, Greenville, SC 29605
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    Two Office Buildings For Sale
    $299,000
    1,800 SF

    Two Office Buildings For Sale

    Two-story office buildings in master-planned park, ideal for investors.

    102 Renaissance Cir, Mauldin, SC 29662
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    Downtown Office Building For Sale
    $1,375,000
    3,444 SF

    Downtown Office Building For Sale

    Office building with 11 private offices and dedicated parking.

    311 Pettigru St, Greenville, SC 29601
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    Freestanding Office/Medical Building For Sale
    $430,000
    2,306 SF

    Freestanding Office/Medical Building For Sale

    Two-story, 2,306 SF office/medical building in established office park.

    4501 Old Spartanburg Rd, Taylors, SC 29687
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    Keeler Mill Road Office Building
    $2,300,000
    15,577 SF

    Keeler Mill Road Office Building

    Well-maintained office building, 15,577 SF, near Travelers Rest downtown.

    1769 Keeler Mill Rd, Travelers Rest, SC 29690
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    Downtown Greenville Redevelopment Opportunity
    $7,000,000
    20,000 SF

    Downtown Greenville Redevelopment Opportunity

    Redevelopment opportunity in Downtown Greenville with mountain views.

    1 Alm Way, Greenville, SC 29601
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    Greenville Office Building For Sale
    $1,500,000
    5,288 SF

    Greenville Office Building For Sale

    Office building with parking near downtown Greenville.

    9 Washington Park, Greenville, SC 29601
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    Two Greenville Office Buildings For Sale
    $2,750,000
    16,778 SF

    Two Greenville Office Buildings For Sale

    Two office buildings with excellent visibility near downtown Greenville.

    429 N Main St, Greenville, SC 29601
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    Office Building Near Laurens Road
    $900,000
    8,030 SF

    Office Building Near Laurens Road

    Two-story office building with ample parking and updated suite.

    8 Sycamore Dr, Greenville, SC 29607
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    Greer Office Building For Sale
    $850,000
    5,000 SF

    Greer Office Building For Sale

    Office building in Greer, South Carolina, with recent upgrades.

    420 The Pkwy, Greer, SC 29650
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    Highway 101 Office Building
    $1,750,000
    12,000 SF

    Highway 101 Office Building

    Office building with easy access and ample parking.

    1431 Highway 101 S, Greer, SC 29651
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    Renovated Office Building For Sale
    $3,995,000
    18,208 SF

    Renovated Office Building For Sale

    Office building with guaranteed rent by U.S. Government.

    319 Pelham Rd, Greenville, SC 29615
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    Greenville Office Building For Sale
    Contact for pricing
    92,614 SF

    Greenville Office Building For Sale

    92,614 SF office building on 4.757 acres in Greenville.

    216 S Pleasantburg Dr, Greenville, SC 29607
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    Prime Office Property in Greenville
    $849,000
    2,140 SF

    Prime Office Property in Greenville

    Modern office space with high visibility and easy access.

    102 W Stone Ave, Greenville, SC 29609
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Greenville County, SC, we suggest to view alternatives - similar 1783 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Greenville County, SC

    Consider similar Off-Market properties in Greenville County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    224 Laurens St

    224 Laurens St

    OFFICE BUILDING • 0.03 Acres
    Value Estimation
    $350,000
    224 Laurens St, Greenville, SC 29601-2680
    View details
    202 Main St

    202 Main St

    OFFICE BUILDING • 0.13 Acres
    Value Estimation
    $345,000
    202 Main St, Fountain Inn, SC 29644-1912
    View details
    3 Research Dr

    3 Research Dr

    OFFICE BUILDING (MULTI-STORY) • 2.07 Acres
    Value Estimation
    $385,000
    3 Research Dr, Greenville, SC 29607-5215
    View details
    217 Memorial Dr

    217 Memorial Dr

    OFFICE BUILDING • 0.27 Acres
    Value Estimation by Request
    217 Memorial Dr, Greer, SC 29650-1520
    View details

    Greenville County, SC Office Buildings Investment Opportunities Market Analysis

    Explore 1803 office buildings for sale in Greenville County, SC, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 65,304,292 square feet of properties for sale, with an estimated market value of $813,449,000.

    Prices for office properties in Greenville County, SC start at $60,000, averaging $783,669, and reaching up to $23,660,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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