Mixed-Use

Key Largo, FL Mixed-use Properties for Sale

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Tavernier, FL Plantation Key, FL Islamorada, FL Homestead, FL Florida City, FL
Mixed-Use Building with Highway Frontage
Updated: Apr 13
Mixed-Use Building with Highway Frontage

92295 Old State Road, Key Largo, FL 33070

$2,895,000
6,241 sqft 0.86 AC lot
313 feet of US‑1 highway frontage on the northbound side
Six separate units/suites connected by exterior walkways
Approximately 6,214 sq. ft. building area on a 37,477 sq. ft. fenced lot
Each unit includes a half bathroom; two additional restrooms accessible via exterior walkways
CBS construction with central air and a metal roof
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92295 Old State Road, Key Largo, FL 33070

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Freestanding Mixed-Use Concrete Building
Updated: Dec 18, 2025
Freestanding Mixed-Use Concrete Building

100636 Overseas Highway, Key Largo, FL 33037

$1,790,000
4,910 sqft 0.18 AC lot
Free‑standing concrete mixed‑use building directly on US‑1 with commercial storefront on the ground floor and residential unit upstairs
Concrete roof and CBS construction; roof: concrete; year built: 1974
Upstairs fully renovated 3BD/3BA apartment with rooms for 3 bedrooms and 3 bathrooms
Impact windows and shutters; approximately 15 ft above sea level
On‑site parking: 5 spaces plus 5 additional rented spaces
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Mixed-Use Property with Ocean Access
Mixed-Use Property with Ocean Access

101900 Overseas Hwy, Key Largo, FL 33037

$10,800,000
2.08 AC lot

Two-acre Florida Keys property includes a gift shop, offices, classrooms, and public water and sewer service.

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High-Frontage Mixed-Use Building with Suites
High-Frontage Mixed-Use Building with Suites

92295 Old State Road, #4A, Key Largo, FL 33070

$2,895,000
6,214 sqft 0.86 AC lot

Concrete mixed-use building with six exterior-access suites and extensive US-1 frontage for flexible retail, office, and medical use.

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Fully Renovated Mixed-Use Property
Fully Renovated Mixed-Use Property

91865 Overseas Highway, Key Largo, FL 33070

$6,495,000

Renovated mixed-use income property with 10 residential units and 5 established commercial tenants.

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Based on your search, we've compiled 69 Potential Opportunities for your consideration. Besides 5 Active listings in Key Largo, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 56 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Oceanfront Mixed-Use Property
Oceanfront Mixed-Use Property

Islamorada, FL 33036

$1,680,000
1,980 sqft 0.16 AC lot

Neighborhood Commercial zoning supports a flexible residential and commercial configuration with Atlantic Ocean frontage.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

Islamorada, FL 33036

$3,300,000
6,071 sqft 0.35 AC lot

Oceanfront commercial property with marine access, wraparound windows, and space for residential and business uses.

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Islamorada Mixed-Use Investment Opportunity
Islamorada Mixed-Use Investment Opportunity

88101 Old Hwy, Plantation Key, FL 33036

Contact for pricing
2,244 sqft

Two-story mixed-use building with income potential in Islamorada.

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Waterfront Marina With Restaurant
Waterfront Marina With Restaurant

90311 Old Highway, Plantation Key, FL 33070

$6,800,000

Village Center zoning supports ocean-access dockage, restaurant operations, parking, and a separate waterfront residence.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Homestead Land in Path of Progress
Homestead Land in Path of Progress

35601 SW 192nd Ave, Homestead, FL 33034

$1,900,000
1.90 AC lot

1.9 acres in rapidly developing area, ideal for investors.

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Corner Development Land Opportunity
Corner Development Land Opportunity

402 SW 6th St, Homestead, FL 33030

$74,500
0.07 AC lot

Corner lot with paved road access in Flood Zone X, within Homestead’s Community Redevelopment Area.

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B-3 Commercial Land
B-3 Commercial Land

318 NE 1st Rd, Homestead, FL 33030

$300,000
0.14 AC lot

Vacant development site with B-3 zoning and electricity available.

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B-3 Commercial Land
B-3 Commercial Land

330 NE 1st Rd, Homestead, FL 33030

$450,000
0.21 AC lot

Vacant B-3 site with electricity available and a public water source.

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Off-Market Properties in Key Largo, FL

Consider similar Off-Market properties in Key Largo, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

106240 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

106240 Overseas Hwy, Key Largo, FL 33037-3129

$245,000
Estimated value
848 sqft 0.11 AC lot
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99336 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

99336 Overseas Hwy, Key Largo, FL 33037-2435

$1,615,000
Estimated value
3,747 sqft 0.87 AC lot
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101641 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

101641 Overseas Hwy, Key Largo, FL 33037-4585

$250,000
Estimated value
3,803 sqft 0.14 AC lot
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98640 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

98640 Overseas Hwy, Key Largo, FL 33037-2337

$365,000
Estimated value
1,020 sqft 1.04 AC lot
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106240 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

106240 Overseas Hwy, Key Largo, FL 33037-3129

$1,750,000
Estimated value
3,936 sqft 0.46 AC lot
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1 Bowen Dr
MIXED USE (COMMERCIAL/INDUSTRIAL)

1 Bowen Dr, Key Largo, FL 33037-2971

$1,560,000
Estimated value
4,412 sqft 0.21 AC lot
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99275 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

99275 Overseas Hwy, Key Largo, FL 33037-4211

$1,530,000
Estimated value
4,855 sqft 0.14 AC lot
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102101 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

102101 Overseas Hwy, Key Largo, FL 33037-4662

$470,000
Estimated value
1,276 sqft 0.18 AC lot
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100470 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

100470 Overseas Hwy, Key Largo, FL 33037-2548

$1,060,000
Estimated value
4,943 sqft 0.44 AC lot
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95165 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

95165 Overseas Hwy, Key Largo, FL 33037-3808

$1,290,000
Estimated value
5,408 sqft 0.19 AC lot
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102940 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

102940 Overseas Hwy, Key Largo, FL 33037-2792

$1,420,000
Estimated value
3,114 sqft 0.11 AC lot
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99411 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

99411 Overseas Hwy, Key Largo, FL 33037-2458

$3,405,000
Estimated value
8,400 sqft 0.90 AC lot
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102991 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

102991 Overseas Hwy, Key Largo, FL 33037-4663

$300,000
Estimated value
3,931 sqft 0.14 AC lot
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100750 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

100750 Overseas Hwy, Key Largo, FL 33037-2584

$330,000
Estimated value
2,240 sqft 0.22 AC lot
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99246 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

99246 Overseas Hwy, Key Largo, FL 33037-2457

$545,000
Estimated value
2,856 sqft 0.66 AC lot
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100760 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

100760 Overseas Hwy, Key Largo, FL 33037

$745,000
Estimated value
3,312 sqft 0.28 AC lot
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100800 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

100800 Overseas Hwy, Key Largo, FL 33037-2506

$1,550,000
Estimated value
7,214 sqft 0.43 AC lot
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104475 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

104475 Overseas Hwy, Key Largo, FL 33037-4822

$305,000
Estimated value
1,000 sqft 0.34 AC lot
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101611 Overseas Hwy
MIXED USE (COMMERCIAL/INDUSTRIAL)

101611 Overseas Hwy, Key Largo, FL 33037-4585

$265,000
Estimated value
3,526 sqft 0.28 AC lot
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Key Largo, FL Mixed-Use Properties Market Trends and Statistics

Explore 61 mixed-use properties for sale in Key Largo, FL, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 17,365 square feet of properties for sale, with an estimated market value of $24,875,000.

Sale prices for multi use buildings in Key Largo, FL start at $1,790,000, averaging $4,975,000, and reaching up to $10,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 14K
Population Growth (5Y) +24.8%
Median Household Income $80,911
College Educated 57.0%

High-Yield Neighborhoods for Investment

Identify Key Largo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
Key Largo - 33037 $1.8M
Tavernier - 33070 $4.1M

Taxes & Financing

Tax Rate (average for all types) 0.67%
Property Tax per SF $10.54 per SF
Tax Rate vs County Average 0.08 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Monroe County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Monroe County

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