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Key Largo, FL Mixed-use Properties for Sale

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Oceanfront Estates with Development Potential
$9,500,000

Oceanfront Estates with Development Potential

95351 Overseas Highway, Key Largo, FL 33037

Oceanfront estates with vacation rental income and development opportunities.

  • Oceanfront gated estate with vacation rental income potential and significant development opportunities.
  • 50 Transferable Development Rights available, allowing for higher development potential.
  • Deep basin and channel providing direct ocean access, including dolphin piling boat slips and a boat ramp.
  • Single Family Residences with ROGO exemptions, offering remodel/rebuild possibilities.
  • Highest approval rate via Monroe County for MIXED‑USE COMMERCIAL development.
Updated: Apr 15
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Key Largo Mixed-Use Property
$1,790,000

Key Largo Mixed-Use Property

100636 Overseas Highway, Key Largo, FL 33037

High-visibility mixed-use property with commercial storefront and residential apartment.

  • High‑visibility location directly on US‑1 in Key Largo, ideal for attracting both local and tourist traffic.
  • Mixed‑use property with a commercial storefront on the ground floor and a fully renovated 3BD/3BA residential apartment upstairs.
  • Versatile commercial space suitable for retail, specialty services, studio, or office use.
  • Durable concrete construction approximately 15 ft above sea level, with impact windows and shutters.
  • Includes 5 on‑site parking spaces plus 5 additional rented spaces.
Updated: Feb 17
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Based on your search, we've compiled 66 Potential Opportunities for your consideration. Besides 2 Active listings in Key Largo, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 56 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Islamorada Mixed-Use Investment Opportunity
$1,195,000
2,244 SF

Islamorada Mixed-Use Investment Opportunity

Two-story mixed-use building with income potential in Islamorada.

88101 Old Hwy, Plantation Key, FL 33036
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Treasure Harbor Marina Business Opportunity
$8,500,000
1,069 SF

Treasure Harbor Marina Business Opportunity

Marina business for sale in Plantation Key, Florida.

200 Treasure Harbor Dr., Plantation Key, FL 33036
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Islamorada Redevelopment Opportunity
$5,500,000
3,312 SF

Islamorada Redevelopment Opportunity

Prime Islamorada property with redevelopment potential in a desirable location.

82929 Overseas Hwy, Islamorada, FL 33036
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Islamorada Mixed-Use Commercial Property
$1,899,000
3,000 SF

Islamorada Mixed-Use Commercial Property

Luxury mixed-use property with highway frontage and flexible commercial/residential space.

87847 Overseas Hwy, Islamorada, FL 33036
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Waterfront Land Development Opportunity
$2,499,000

Waterfront Land Development Opportunity

Rare waterfront land in Islamorada, Florida, with development potential.

90291 Old Highway, Plantation Key, FL 33070
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Homestead Corner Lot Development Opportunity
$86,000
0.07 Acres

Homestead Corner Lot Development Opportunity

Corner lot in Homestead's Community Redevelopment Area, flexible development potential.

402 SW 6th St, Homestead, FL 33030
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Homestead Commercial Property For Sale
$2,100,000

Homestead Commercial Property For Sale

Freestanding 6,212 SF building on 15,000 SF lot in Homestead.

395 N Flagler Ave, Homestead, FL 33030
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Commercial Lot in Homestead, FL
$300,000
0.13 Acres

Commercial Lot in Homestead, FL

6,000 SF commercial lot zoned B-3 in Homestead, Florida.

318 NE 1st Rd, Homestead, FL 33030
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Explore Off-Market Properties in Key Largo, FL

Consider similar Off-Market properties in Key Largo, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

106240 Overseas Hwy

106240 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 848 SF
Value Estimation by Request
106240 Overseas Hwy, Key Largo, FL 33037-3129
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99336 Overseas Hwy

99336 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,747 SF
Value Estimation
$1,615,000
99336 Overseas Hwy, Key Largo, FL 33037-2435
View details
101641 Overseas Hwy

101641 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,803 SF
Value Estimation by Request
101641 Overseas Hwy, Key Largo, FL 33037-4585
View details
98640 Overseas Hwy

98640 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,020 SF
Value Estimation by Request
98640 Overseas Hwy, Key Largo, FL 33037-2337
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106240 Overseas Hwy

106240 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,936 SF
Value Estimation
$1,785,000
106240 Overseas Hwy, Key Largo, FL 33037-3129
View details
1 Bowen Dr

1 Bowen Dr

MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,412 SF
Value Estimation
$1,575,000
1 Bowen Dr, Key Largo, FL 33037-2971
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99275 Overseas Hwy

99275 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,855 SF
Value Estimation
$1,490,000
99275 Overseas Hwy, Key Largo, FL 33037-4211
View details
102101 Overseas Hwy

102101 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,276 SF
Value Estimation by Request
102101 Overseas Hwy, Key Largo, FL 33037-4662
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100470 Overseas Hwy

100470 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,943 SF
Value Estimation
$1,095,000
100470 Overseas Hwy, Key Largo, FL 33037-2548
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95165 Overseas Hwy

95165 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,408 SF
Value Estimation
$1,365,000
95165 Overseas Hwy, Key Largo, FL 33037-3808
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102940 Overseas Hwy

102940 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,114 SF
Value Estimation
$1,425,000
102940 Overseas Hwy, Key Largo, FL 33037-2792
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99411 Overseas Hwy

99411 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,400 SF
Value Estimation
$3,425,000
99411 Overseas Hwy, Key Largo, FL 33037-2458
View details
102991 Overseas Hwy

102991 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,931 SF
Value Estimation
$625,000
102991 Overseas Hwy, Key Largo, FL 33037-4663
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100750 Overseas Hwy

100750 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,240 SF
Value Estimation by Request
100750 Overseas Hwy, Key Largo, FL 33037-2584
View details
99246 Overseas Hwy

99246 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,856 SF
Value Estimation
$545,000
99246 Overseas Hwy, Key Largo, FL 33037-2457
View details
100760 Overseas Hwy

100760 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,312 SF
Value Estimation
$745,000
100760 Overseas Hwy, Key Largo, FL 33037
View details
100800 Overseas Hwy

100800 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 7,214 SF
Value Estimation
$1,550,000
100800 Overseas Hwy, Key Largo, FL 33037-2506
View details
104475 Overseas Hwy

104475 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,000 SF
Value Estimation by Request
104475 Overseas Hwy, Key Largo, FL 33037-4822
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101611 Overseas Hwy

101611 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,526 SF
Value Estimation
$560,000
101611 Overseas Hwy, Key Largo, FL 33037-4585
View details
100460 Overseas Hwy

100460 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,200 SF
Value Estimation
$1,290,000
100460 Overseas Hwy, Key Largo, FL 33037-2547
View details
99264 Overseas Hwy

99264 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,679 SF
Value Estimation
$1,150,000
99264 Overseas Hwy, Key Largo, FL 33037-2457
View details
98310 Overseas Hwy

98310 Overseas Hwy

MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,293 SF
Value Estimation by Request
98310 Overseas Hwy, Key Largo, FL 33037-2370
View details

Key Largo, FL Mixed-Use Properties Investment Opportunities Market Analysis

Explore 58 mixed-use properties for sale in Key Largo, FL on our real estate platform. These investment opportunities span a total of 1,047,647 square feet of properties for sale, with an estimated market value of $22,030,000.

Sale prices for multi use buildings in Key Largo, FL start at $215,000, averaging $564,871, and reaching up to $3,405,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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