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    Key Largo, FL Mixed-use Properties for Sale

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    Tavernier, FL Islamorada, FL Plantation Key, FL
    Prime US-1 Mixed-Use Opportunity
    $2,895,000
    6,241 SF

    Prime US-1 Mixed-Use Opportunity

    92295 Old State Road, Key Largo, FL 33070

    Mixed-use commercial building with highway frontage in Tavernier.

    • Prime US‑1 highway frontage (313 feet) in Tavernier with high visibility and traffic.
    • Mixed‑use commercial building with approximately 6,214 sq. ft. of space.
    • Six separate units/suites, providing flexibility for multiple tenants or diverse business operations.
    • Located on the northbound side of US‑1 with convenient access to the southbound lane.
    • Suitable for various uses: retail, office, medical, educational, fitness, or storage.
    Updated: Apr 13
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    Key Largo Mixed-Use Property
    $1,790,000
    4,910 SF

    Key Largo Mixed-Use Property

    100636 Overseas Highway, Key Largo, FL 33037

    High-visibility mixed-use property with commercial storefront and residential apartment.

    • High‑visibility location directly on US‑1 in Key Largo.
    • Mixed‑use property with commercial storefront and renovated 3BD/3BA residential apartment.
    • Solid concrete construction with impact windows and shutters.
    • Flexible zoning with endless potential.
    • Includes 10 parking spaces (5 on‑site, 5 rented).
    Updated: Dec 18, 2025
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    Key Largo Commercial Opportunity
    Contact for pricing
    2,400 SF

    Key Largo Commercial Opportunity

    Highway frontage building with upstairs space for lease.

    106600 Overseas Highway, Key Largo, FL 33037
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    Oceanfront Estates with Development Potential
    $9,500,000
    2,489 SF

    Oceanfront Estates with Development Potential

    Gated oceanfront estates with commercial zoning and development opportunities.

    95351 Overseas Highway, Key Largo, FL 33037
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    Based on your search, we've compiled 68 Potential Opportunities for your consideration. Besides 4 Active listings in Key Largo, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 56 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Commercial Building in Plantation Key
    $1,195,000
    2,244 SF

    Mixed-Use Commercial Building in Plantation Key

    Two-story mixed-use building with highway frontage and income potential.

    88101 Old Highway, Plantation Key, FL 33036
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    Islamorada Mixed-Use Investment Opportunity
    $1,195,000
    2,244 SF

    Islamorada Mixed-Use Investment Opportunity

    Two-story mixed-use building with income potential in Islamorada.

    88101 Old Hwy, Plantation Key, FL 33036
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    Islamorada Redevelopment Opportunity
    $5,500,000
    3,312 SF

    Islamorada Redevelopment Opportunity

    Prime Islamorada property with redevelopment potential in a desirable location.

    82929 Overseas Hwy, Islamorada, FL 33036
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    Islamorada Mixed-Use Commercial Property
    $1,899,000
    3,000 SF

    Islamorada Mixed-Use Commercial Property

    Luxury mixed-use property with highway frontage and flexible commercial/residential space.

    87847 Overseas Hwy, Islamorada, FL 33036
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Homestead Land in Path of Progress
    $1,900,000
    1.92 Acres

    Homestead Land in Path of Progress

    1.9 acres in rapidly developing area, ideal for investors.

    35601 SW 192nd Ave, Homestead, FL 33034
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    Homestead Mixed-Use Development Opportunity
    $86,000
    0.07 Acres

    Homestead Mixed-Use Development Opportunity

    Corner lot in Homestead's Community Redevelopment Area.

    402 SW 6th St, Homestead, FL 33030
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    Commercial Property in Homestead, Florida
    $2,100,000
    6,212 SF

    Commercial Property in Homestead, Florida

    Freestanding 6,212 SF building on 15,000 SF lot.

    395 N Flagler Ave, Homestead, FL 33030
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    Commercial Lot in Homestead
    $300,000
    0.14 Acres

    Commercial Lot in Homestead

    Vacant lot zoned B-3, ideal for various commercial uses.

    318 NE 1st Rd, Homestead, FL 33030
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    Off-Market Properties in Key Largo, FL

    Consider similar Off-Market properties in Key Largo, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    106240 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    848 SF Lot: 0.11 Acres
    Value Estimation by Request

    106240 Overseas Hwy, Key Largo, FL 33037-3129

    View details
    99336 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,747 SF Lot: 0.87 Acres
    Estimated value
    $1,615,000

    99336 Overseas Hwy, Key Largo, FL 33037-2435

    View details
    101641 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,803 SF Lot: 0.14 Acres
    Value Estimation by Request

    101641 Overseas Hwy, Key Largo, FL 33037-4585

    View details
    98640 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    1,020 SF Lot: 1.04 Acres
    Value Estimation by Request

    98640 Overseas Hwy, Key Largo, FL 33037-2337

    View details
    106240 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,936 SF Lot: 0.46 Acres
    Estimated value
    $1,785,000

    106240 Overseas Hwy, Key Largo, FL 33037-3129

    View details
    1 Bowen Dr
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    4,412 SF Lot: 0.21 Acres
    Estimated value
    $1,575,000

    1 Bowen Dr, Key Largo, FL 33037-2971

    View details
    99275 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    4,855 SF Lot: 0.14 Acres
    Estimated value
    $1,490,000

    99275 Overseas Hwy, Key Largo, FL 33037-4211

    View details
    102101 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    1,276 SF Lot: 0.18 Acres
    Value Estimation by Request

    102101 Overseas Hwy, Key Largo, FL 33037-4662

    View details
    100470 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    4,943 SF Lot: 0.44 Acres
    Estimated value
    $1,095,000

    100470 Overseas Hwy, Key Largo, FL 33037-2548

    View details
    95165 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    5,408 SF Lot: 0.19 Acres
    Estimated value
    $1,365,000

    95165 Overseas Hwy, Key Largo, FL 33037-3808

    View details
    102940 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,114 SF Lot: 0.11 Acres
    Estimated value
    $1,425,000

    102940 Overseas Hwy, Key Largo, FL 33037-2792

    View details
    99411 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    8,400 SF Lot: 0.90 Acres
    Estimated value
    $3,425,000

    99411 Overseas Hwy, Key Largo, FL 33037-2458

    View details
    102991 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,931 SF Lot: 0.14 Acres
    Estimated value
    $625,000

    102991 Overseas Hwy, Key Largo, FL 33037-4663

    View details
    100750 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    2,240 SF Lot: 0.22 Acres
    Value Estimation by Request

    100750 Overseas Hwy, Key Largo, FL 33037-2584

    View details
    99246 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    2,856 SF Lot: 0.66 Acres
    Estimated value
    $545,000

    99246 Overseas Hwy, Key Largo, FL 33037-2457

    View details
    100760 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,312 SF Lot: 0.28 Acres
    Estimated value
    $745,000

    100760 Overseas Hwy, Key Largo, FL 33037

    View details
    100800 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    7,214 SF Lot: 0.43 Acres
    Estimated value
    $1,550,000

    100800 Overseas Hwy, Key Largo, FL 33037-2506

    View details
    104475 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    1,000 SF Lot: 0.34 Acres
    Value Estimation by Request

    104475 Overseas Hwy, Key Largo, FL 33037-4822

    View details
    101611 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    3,526 SF Lot: 0.28 Acres
    Estimated value
    $560,000

    101611 Overseas Hwy, Key Largo, FL 33037-4585

    View details
    100460 Overseas Hwy
    MIXED USE (COMMERCIAL/INDUSTRIAL)
    8,200 SF Lot: 0.49 Acres
    Estimated value
    $1,290,000

    100460 Overseas Hwy, Key Largo, FL 33037-2547

    View details

    Key Largo, FL Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 60 mixed-use properties for sale in Key Largo, FL, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 13,640 square feet of properties for sale, with an estimated market value of $14,285,000.

    Sale prices for multi use buildings in Key Largo, FL start at $1,790,000, averaging $4,761,666, and reaching up to $9,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 14K
    Population Growth (5Y) +24.8%
    Median Household Income $80,911
    College Educated 57.0%

    High-Yield Neighborhoods for Investment

    Identify Key Largo submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    Tavernier $3M
    Key Largo $5.6M

    Taxes & Financing

    Tax Rate (average for all types) 0.67%
    Property Tax per SF $10.54 per sq ft
    Tax Rate vs County Average 0.08 pp below county avg
    Average Loan-to-Value 65.0%

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