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    Durham, NC Mixed-use Properties for Lease

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    Luxury Mixed-Use Development Near Duke
    Updated: Sep 25, 2025
    Luxury Mixed-Use Development Near Duke

    2812 & 2816 Erwin Rd |, Durham, NC 27705

    $25 SF/Yr
    118,000 sqft
    Walking distance to Duke University Hospital, Duke University, Durham VA Hospital, and Lenox Baker Children’s Hospital
    Class A mixed‑use development with luxury apartments, offices, and retail
    Convenient to US 15‑501 and NC 147/Durham Freeway
    Ample surface and structured parking available
    Property adjoins a 141‑key AC Hotel by Marriott
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    Mixed-Use Development Opportunity in Durham
    Updated: Mar 6
    Mixed-Use Development Opportunity in Durham

    3214 Hillsborough Road, Durham, NC 27705

    Contact for pricing
    71,652 sqft 12.00 AC lot
    Class‑A mixed‑use development featuring retail, restaurants, and residential dwellings.
    Located one mile from Duke University Main Campus & Hospital.
    12 AC total property size.
    71,652 SF of Retail space.**
    Best‑in‑class retail and restaurant opportunities.**
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    Erwin Road Mixed-Use Retail Space
    Erwin Road Mixed-Use Retail Space

    2812 & 2816 Erwin Rd |, Durham, NC 27705

    Contact for pricing
    118,000 sqft

    Class A retail space in mixed-use development near Duke University.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Mixed-Use Development
    Mixed-Use Development

    5720 - 5850 Fayetteville Rd., Durham, NC 27713

    Contact for pricing

    Combines retail, office, and residential components within one development.

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    Downtown Durham Mixed-Use Asset
    Downtown Durham Mixed-Use Asset

    601 West Main Street, Durham, NC 27701

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    Mixed-use property in the heart of Downtown Durham.

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    Mixed-Use Redevelopment Opportunity
    Mixed-Use Redevelopment Opportunity

    University Dr & Shannon Rd, Durham, NC 27707, USA, Durham, NC 27707

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    Mixed-use redevelopment with main street setting.

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    Mixed-Use Development Opportunity in Durham
    Mixed-Use Development Opportunity in Durham

    3214 Hillsborough Rd, Durham, NC 27705

    Contact for pricing

    Mixed-use development with retail, restaurants, and residential dwellings.

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    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 7 Active listings in Durham, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Mixed-Use and Industrial Buildings
    Mixed-Use and Industrial Buildings

    3101 Industrial Drive, Raleigh, NC 27609

    Contact for pricing
    568,560 sqft

    15 mixed-use and light industrial buildings in Midtown Raleigh.

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    Fenton Mixed-Use Destination Pad
    Fenton Mixed-Use Destination Pad

    1085 Fenton Gateway Drive, Cary, NC 27511

    Contact for pricing

    Pad ready for sublease in Cary's Fenton Gateway.

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    Mixed-Use Development with Food Spaces
    Mixed-Use Development with Food Spaces

    Wake Forest Road & Whitaker Road, Raleigh, NC 27608

    Contact for pricing

    Mixed-use development with food and beverage spaces for rent.

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    Mixed-Use Destination in Cary
    Mixed-Use Destination in Cary

    1085 Fenton Gtwy Dr, Cary, NC 27511

    Contact for pricing

    Vertically integrated mixed-use destination for rent in Cary.

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    Similar Spaces for Sale in Durham, NC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Downtown Durham Multifamily Development Opportunity
    Downtown Durham Multifamily Development Opportunity

    6 Grace Ln, Durham, NC 27701

    Contact for pricing
    8,721 sqft 1.65 AC lot

    Entitled mixed-use site with 201 residential units and commercial space.

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    Downtown Durham Mixed-Use Property
    Downtown Durham Mixed-Use Property

    114 E Main St, Durham, NC 27701

    Contact for pricing
    2,386 sqft

    Historic building with modern upgrades, suitable for multiple uses.

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    Retail and Office Development Site
    Retail and Office Development Site

    5802 & 5904 S Miami Blvd |, Durham, NC 27560

    Contact for pricing
    33 sqft

    Approved site for 33,000 SF retail and office development.

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    Commercial Land Development Site
    Commercial Land Development Site

    2214 T W Alexander Drive, Durham, NC 27703

    $2,755,000
    5.79 AC lot

    Commercial General zoning supports retail, office, hospitality, mixed-use, and multifamily development concepts.

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    Durham Mixed-Use Asset Near Duke
    Durham Mixed-Use Asset Near Duke

    2816 Erwin Rd, Durham, NC 27705

    Contact for pricing
    105,055 sqft

    Mixed-use asset near Duke University with multifamily, retail, office.

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    Downtown Hi-Rise Redevelopment Site
    Downtown Hi-Rise Redevelopment Site

    216 Rigsbee Ave, Durham, NC 27701

    Contact for pricing

    Downtown Durham redevelopment site with approved demolition and an 11-story hi-rise redevelopment plan.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Jarrettsville Corridor
    Prime Land in Jarrettsville Corridor

    1753, Jarrettsville, MD 21084

    Contact for pricing
    1.55 AC lot

    1.55 acre parcel in Jarrettsville's business corridor.

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    Agricultural Land Parcel
    Agricultural Land Parcel

    1057 Constitution Road SW, Atlanta, GA 30315

    $1,850/Mo

    Unimproved land with available water and electricity supports agricultural or compatible commercial use.

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    Commercial Land with Highway Access
    Commercial Land with Highway Access

    4.12 Acres Al Highway 35, Rainsville, AL 35986

    $6,000/Mo

    Prime commercial land on Highway 35 in Rainsville with an ALDOT-approved entrance and sewer available.

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    Redevelopment Opportunity on Howe Avenue
    Redevelopment Opportunity on Howe Avenue

    583 Howe Ave, Shelton, CT 06484

    Contact for pricing
    0.55 AC lot

    0.55-acre corner lot suitable for multifamily or mixed-use development.

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    Durham, NC Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in Durham, NC with 7 listings featured on our commercial real estate exchange. The current inventory includes 307,652 square feet of properties with an estimated lease value of $25 SF/Yr.

    Estimated lease rates for Mixed-use properties in Durham, NC average $25 SF/Yr.
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    Most Searched ZIP Codes in Durham, NC

    • 27705
    • 27701
    • 27707

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