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    Durham, NC
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    Durham, NC Mixed-use Properties for Lease

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    Chapel Hill, NC Raleigh, NC Cary, NC
    8 results
    Luxury Mixed-Use Development Near Duke
    $25 SF/Yr
    118,000 SF

    Luxury Mixed-Use Development Near Duke

    2812 & 2816 Erwin Rd |, Durham, NC 27705

    Class A mixed-use development near Duke University and hospitals.

    • Walking distance to Duke University Hospital, Duke University, Durham VA Hospital, and Lenox Baker Children’s Hospital
    • Class A mixed‑use development with luxury apartments, offices, and retail
    • Convenient to US 15‑501 and NC 147/Durham Freeway
    • Ample surface and structured parking available
    • Property adjoins a 141‑key AC Hotel by Marriott
    Updated: Sep 25, 2025
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    Erwin Road Mixed-Use Retail Space
    Contact for pricing
    118,000 SF

    Erwin Road Mixed-Use Retail Space

    2812 & 2816 Erwin Rd |, Durham, NC 27705

    Class A retail space in mixed-use development near Duke University.

    • Walking distance to Duke University Hospital, Duke University, Durham VA Hospital, and Lenox Baker Children’s Hospital
    • Class A mixed‑use development with luxury apartments, offices, and retail
    • Ample surface and structured parking
    • Convenient to US 15‑501 and NC 147/Durham Freeway
    • Property adjoins a 141‑key AC Hotel by Marriott
    Updated: Sep 25, 2025
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    Mixed-Use Development Opportunity in Durham
    Contact for pricing
    71,652 SF

    Mixed-Use Development Opportunity in Durham

    Mixed-use development site with retail, restaurant, and residential potential.

    3214 Hillsborough Road, Durham, NC 27705
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    Downtown Durham Mixed-Use Asset
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    Downtown Durham Mixed-Use Asset

    Mixed-use property in the heart of Downtown Durham.

    601 West Main Street, Durham, NC 27701
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    Mixed-Use Redevelopment Opportunity
    Contact for pricing

    Mixed-Use Redevelopment Opportunity

    Mixed-use redevelopment with main street setting.

    University Dr & Shannon Rd, Durham, NC 27707, USA, Durham, NC 27707
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    Durham Flex/Retail Space Available
    Contact for pricing
    11,102 SF

    Durham Flex/Retail Space Available

    11,102 SF flex/retail space in growing Durham area.

    305 S Roxboro St, Durham, NC 27701
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    Versatile Building in Prime Location
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    Versatile Building in Prime Location

    Adaptable building suitable for restaurants, fitness, or office use.

    211 Rigsbee Ave, Durham, NC 27701
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    Mixed-Use Development Opportunity in Durham
    Contact for pricing

    Mixed-Use Development Opportunity in Durham

    Mixed-use development with retail, restaurants, and residential dwellings.

    3214 Hillsborough Rd, Durham, NC 27705
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    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 8 Active listings in Durham, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Fenton Mixed-Use Destination Pad
    Contact for pricing

    Fenton Mixed-Use Destination Pad

    Pad ready for sublease in Cary's Fenton Gateway.

    1085 Fenton Gateway Drive, Cary, NC 27511
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    Mixed-Use Development with Food Spaces
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    Mixed-Use Development with Food Spaces

    Mixed-use development with food and beverage spaces for rent.

    Wake Forest Road & Whitaker Road, Raleigh, NC 27608
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    Mixed-Use Destination in Cary
    Contact for pricing

    Mixed-Use Destination in Cary

    Vertically integrated mixed-use destination for rent in Cary.

    1085 Fenton Gtwy Dr, Cary, NC 27511
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    Creative Office and Retail Space
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    45,000 SF

    Creative Office and Retail Space

    Remodeled mixed-use property with creative office, retail, and storage space.

    1501 Sunrise Ave, Raleigh, NC 27608
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    Similar Spaces for Sale in Durham, NC

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Downtown Durham Redevelopment Opportunity
    $1,000,000

    Downtown Durham Redevelopment Opportunity

    Mixed-use redevelopment opportunity in vibrant Downtown Durham on Main Street.

    113 West Main Street, Durham, NC 27701
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    Downtown Durham Multifamily Development Opportunity
    Contact for pricing
    8,721 SF

    Downtown Durham Multifamily Development Opportunity

    Entitled mixed-use site with 201 residential units and commercial space.

    6 Grace Ln, Durham, NC 27701
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    Durham Automotive/Retail Opportunity
    $750,000
    2,640 SF

    Durham Automotive/Retail Opportunity

    Vacant property in Durham with high visibility and strong potential.

    901 E Trinity Ave, Durham, NC 27704
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    Downtown Durham Mixed-Use Property
    $1,400,000
    4,500 SF

    Downtown Durham Mixed-Use Property

    Mixed-use property in Downtown Durham with office and residential spaces.

    116 East Main Street, Durham, NC 27701
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    Multi-Purpose Building on 2.24 Acres
    $799,900
    1.27 Acres

    Multi-Purpose Building on 2.24 Acres

    Well-maintained multi-purpose building on 2.24 acres with lease in place.

    315 Southerland St, Durham, NC 27703
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    Retail and Office Development Site
    Contact for pricing

    Retail and Office Development Site

    Approved site for 33,000 SF retail and office development.

    5802 & 5904 S Miami Blvd |, Durham, NC 27560
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    Downtown Durham Mixed-Use Property
    $1,400,000
    4,500 SF

    Downtown Durham Mixed-Use Property

    Mixed-use property in Downtown Durham with office and residential spaces.

    116 E Main, Durham, NC 27701
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Jarrettsville Corridor
    Contact for pricing

    Prime Land in Jarrettsville Corridor

    1.55 acre parcel in Jarrettsville's business corridor.

    1753, Jarrettsville, MD 21084
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    Harrisburg Redevelopment Site For Rent
    Contact for pricing
    11,000 SF

    Harrisburg Redevelopment Site For Rent

    5.85-acre redevelopment site approved for 92 residential units.

    2150 Herr Street, Harrisburg, PA 17103
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    Atlanta Land for Lease
    $1,850/Mo

    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315
    View details
    Prime Commercial Acres For Lease
    $6,000/Mo

    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986
    View details

    Durham, NC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Durham, NC with 8 listings featured on our commercial real estate exchange. The current inventory includes 118,000 square feet of properties with an estimated lease value of $25 SF/Yr.

    Estimated lease rates for Mixed-use properties in Durham, NC begin at $25 SF/Yr, with an average of $25 SF/Yr and extend to $25 SF/Yr.
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    Most Searched ZIP Codes in Durham, NC

    • 27705
    • 27701
    • 27707

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