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    East Stroudsburg, PA Medical Offices for Sale

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    East Stroudsburg Commercial Building For Sale
    $600,000
    3,360 SF

    East Stroudsburg Commercial Building For Sale

    209 Skyline Dr, East Stroudsburg, PA 18301

    Freestanding 3,360 sq ft brick building on 0.59 acres.

    • High‑visibility location at a busy intersection with over 19,000 cars passing daily.
    • Versatile C‑2 zoning suitable for various businesses (medical, restaurant, retail, bank).
    • Freestanding 4,000 sq ft brick building with a 3‑lane drive‑thru and 20+ parking spaces.
    • Located in the Pocono Mountains, a high‑tourism area with $27.9 million in annual revenue.
    • Features include 4 private offices, 2 restrooms, a vault, and a well‑equipped mechanical room.
    Updated: Jun 10, 2025
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    East Stroudsburg Medical/Office Building
    $599,000
    5,484 SF

    East Stroudsburg Medical/Office Building

    371 E Brown St, East Stroudsburg, PA 18301

    5,484 sq ft commercial building in Poconos medical district.

    • Prime 5,484 sq. ft. commercial medical/office building on 1.07 acres in the Poconos medical district.
    • Three units: 2,600 sq. ft. owner‑occupied upstairs and two 1,300 sq. ft. units on the lower level.
    • Ideal for medical or professional use with ample on‑site parking and high daily traffic.
    • Located near Route 80, East Stroudsburg University, and Lehigh Valley Hospital‑Pocono.
    • Great opportunity for investors or owner‑users in a high‑demand location.
    Updated: Aug 18, 2025
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    East Stroudsburg Medical Office Building
    $1,899,000
    13,541 SF

    East Stroudsburg Medical Office Building

    13,600 SF medical office building in growing healthcare hub.

    500 Vna Rd, East Stroudsburg, PA 18301
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    East Stroudsburg Medical Office Building
    $325,000
    1,888 SF

    East Stroudsburg Medical Office Building

    1,888 SF Medical Office, 100% Occupied

    383 Brown St, East Stroudsburg, PA 18301
    View details
    Based on your search, we've compiled 63 Potential Opportunities for your consideration. Besides 4 Active listings in East Stroudsburg, PA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 54 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Medical Office Condo in Tobyhanna, PA
    $1,568,467
    6,067 SF

    Prime Medical Office Condo in Tobyhanna, PA

    High-Yield Medical Office Investment

    100 Community Dr, Tobyhanna, PA 18466
    View details
    Professional/Medical Office Building For Sale
    $2,950,000
    18,444 SF

    Professional/Medical Office Building For Sale

    18,400 sq ft professional/medical office building in Tobyhanna, PA.

    300 Community Dr, Tobyhanna, PA 18466
    View details
    Turnkey Medical Office Building
    $6,000,000
    36,748 SF

    Turnkey Medical Office Building

    Adaptable medical office building with surgery center and expansion potential.

    3729 Easton Nazareth Hwy, Easton, PA 18045
    View details
    Medical/Professional Office Space Available
    Contact for pricing
    4,750 SF

    Medical/Professional Office Space Available

    4,750 SF suite ideal for medical or professional office use.

    3735 Easton Nazareth Hwy, Easton, PA 18045
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    East Stroudsburg Land with Views
    $109,995
    3.50 Acres

    East Stroudsburg Land with Views

    3.5 acres of B-2 zoned land with lake views.

    121 Tree Ln, East Stroudsburg, PA 18301
    View details

    Explore Off-Market Properties in East Stroudsburg, PA

    Consider similar Off-Market properties in East Stroudsburg, PA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    125 Smithfield Ln

    125 Smithfield Ln

    Medical offices
    Value Estimation by Request
    125 Smithfield Ln, East Stroudsburg, PA 18301
    View details
    125 Smithfield Ln

    125 Smithfield Ln

    Medical offices • 40,000 SF
    Value Estimation by Request
    125 Smithfield Ln, East Stroudsburg, PA 18301
    View details
    383 Brown St

    383 Brown St

    Medical offices • 1,888 SF
    Value Estimation by Request
    383 Brown St, East Stroudsburg, PA 18301
    View details
    4455 Milford Rd

    4455 Milford Rd

    Office space • 47,427 SF
    Value Estimation by Request
    4455 Milford Rd, East Stroudsburg, PA 18301
    View details
    216 Skyline Dr

    216 Skyline Dr

    Medical offices • 34,000 SF
    Value Estimation by Request
    216 Skyline Dr, East Stroudsburg, PA 18301
    View details
    173 Brown St

    173 Brown St

    MEDICAL BUILDING • 12,240 SF
    Value Estimation by Request
    173 Brown St, East Stroudsburg, PA 18301
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    175 Brown St

    175 Brown St

    MEDICAL BUILDING • 15,776 SF
    Value Estimation by Request
    175 Brown St, East Stroudsburg, PA 18301-3098
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    5221 Milford Rd

    5221 Milford Rd

    MEDICAL BUILDING • 1,991 SF
    Value Estimation
    $215,000
    5221 Milford Rd, East Stroudsburg, PA 18302-9149
    View details
    243 Brown St

    243 Brown St

    MEDICAL BUILDING • 4,440 SF
    Value Estimation
    $460,000
    243 Brown St, East Stroudsburg, PA 18301-3005
    View details
    300 Brown St

    300 Brown St

    MEDICAL BUILDING • 6,970 SF
    Value Estimation
    $775,000
    300 Brown St, East Stroudsburg, PA 18301-3012
    View details
    296 Brown St

    296 Brown St

    MEDICAL BUILDING • 8,064 SF
    Value Estimation by Request
    296 Brown St, East Stroudsburg, PA 18301-3011
    View details
    214 Washington St

    214 Washington St

    MEDICAL BUILDING • 1,260 SF
    Value Estimation
    $110,000
    214 Washington St, East Stroudsburg, PA 18301-2821
    View details
    274 276th Prospect St

    274 276th Prospect St

    MEDICAL CLINIC • 2,568 SF
    Value Estimation by Request
    274 276th Prospect St, East Stroudsburg, PA 18301
    View details
    25 Courtland St

    25 Courtland St

    MEDICAL BUILDING • 4,232 SF
    Value Estimation
    $160,000
    25 Courtland St, East Stroudsburg, PA 18301-2101
    View details
    260 Prospect St

    260 Prospect St

    MEDICAL CLINIC • 0.23 Acres
    Value Estimation by Request
    260 Prospect St, East Stroudsburg, PA 18301
    View details
    739 Milford Rd

    739 Milford Rd

    MEDICAL BUILDING • 2,800 SF
    Value Estimation
    $280,000
    739 Milford Rd, East Stroudsburg, PA 18301-1307
    View details
    292 Brown St

    292 Brown St

    MEDICAL BUILDING • 3,120 SF
    Value Estimation
    $365,000
    292 Brown St, East Stroudsburg, PA 18301-3006
    View details
    181 Brown St

    181 Brown St

    MEDICAL CLINIC • 1.49 Acres
    Value Estimation by Request
    181 Brown St, East Stroudsburg, PA 18301-3004
    View details
    600 Plz Ct

    600 Plz Ct

    MEDICAL BUILDING • 15,960 SF
    Value Estimation by Request
    600 Plz Ct, East Stroudsburg, PA 18301-8263
    View details
    162 Brown St

    162 Brown St

    MEDICAL CLINIC • 2,690 SF
    Value Estimation
    $305,000
    162 Brown St, East Stroudsburg, PA 18301
    View details

    East Stroudsburg, PA Medical Offices Investment Opportunities Market Analysis

    Explore 58 medical offices for sale in East Stroudsburg, PA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 1,592,554 square feet of properties for sale, with an estimated market value of $35,343,000.

    Prices for medical spaces in East Stroudsburg, PA start at $110,000, averaging $1,104,468, and reaching up to $14,025,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Most Searched ZIP Codes in East Stroudsburg, PA

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